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Mammalian Phenotype Browser
Term Detail
MP term:emphysema
MP id: MP:0001958
Definition: an abnormal condition of the lung characterized by permanent enlargement of airspaces distal to the terminal bronchioles, accompanied by destruction of their walls and without obvious fibrosis; results in decreased respiratory function including increased air retention and reduced exchange of gases
Number of paths to term: 2

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship

mammalian phenotype
        is-arespiratory system phenotype
                is-aabnormal respiratory system morphology
                        is-aabnormal lung morphology
                                is-aabnormal pulmonary alveolar system morphology
                                        is-aabnormal pulmonary acinus morphology
                                                is-aabnormal pulmonary alveolar duct morphology +
                                                is-aabnormal pulmonary alveolar sac morphology +
                                                is-aabnormal pulmonary alveolus morphology +
                                                is-aabnormal pulmonary interalveolar septum morphology +
                                                is-aabnormal respiratory bronchiole morphology +
                                                is-aemphysema [MP:0001958] (84 genotypes, 84 annotations)

mammalian phenotype
        is-arespiratory system phenotype
                is-aabnormal respiratory system physiology
                        is-aabnormal alveolar macrophage physiology
                        is-aabnormal bronchoconstrictive response +
                        is-aabnormal lung elastance +
                        is-aabnormal lung hysteresivity
                        is-aabnormal lung tissue damping +
                        is-aabnormal mucociliary clearance +
                        is-aabnormal pulmonary circulation +
                        is-aabnormal respiration +
                        is-aabnormal respiratory epithelium physiology +
                        is-aabnormal surfactant physiology +
                        is-aatelectasis +
                        is-aemphysema [MP:0001958] (84 genotypes, 84 annotations)
                        is-aincreased lung apoptosis +
                        is-apleural effusion +
                        is-apulmonary edema +
                        is-apulmonary hyaline membrane formation +
                        is-aresistant to pulmonary hyaline membrane formation
                        is-arespiratory acidosis
                        is-arespiratory system inflammation +

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MGI 6.08
The Jackson Laboratory