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Mammalian Phenotype Browser
Term Detail
MP term:abnormal dopamine level
Synonym: abnormal dopaminergic levels
MP id: MP:0001905
Definition: greater or less than the normal amount of this catecholamine neurotransmitter and neurohormone, derived from tyrosine and the precursor to norepinephrine and epinephrine; functions as a neurotransmitter in the brain and as a hormone to inhibit the release of prolactin from the anterior lobe of the pituitary
Number of paths to term: 2

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship


mammalian phenotype
        is-ahomeostasis/metabolism phenotype
                is-aabnormal homeostasis
                        is-aabnormal catecholamine level
                                is-aabnormal adrenaline level +
                                is-aabnormal dopamine level [MP:0001905] (169 genotypes, 178 annotations)
                                        is-adecreased dopamine level
                                        is-aincreased dopamine level
                                is-aabnormal noradrenaline level +
                                is-aabnormal urine catecholamine level


mammalian phenotype
        is-anervous system phenotype
                is-aabnormal nervous system physiology
                        is-aabnormal autonomic nervous system physiology +
                        is-aabnormal blood-brain barrier function
                        is-aabnormal blood-cerebrospinal fluid barrier function
                        is-aabnormal central pattern generator function +
                        is-aabnormal cerebrospinal fluid production +
                        is-aabnormal dopamine level [MP:0001905] (169 genotypes, 178 annotations)
                                is-adecreased dopamine level
                                is-aincreased dopamine level
                        is-aabnormal embryonic neuroepithelial cell proliferation +
                        is-aabnormal endoneurial fluid pressure +
                        is-aabnormal ependyma motile cilium physiology +
                        is-aabnormal glial cell physiology +
                        is-aabnormal hippocampus physiology
                        is-aabnormal hypothalamus physiology +
                        is-aabnormal myelination +
                        is-aabnormal nervous system electrophysiology +
                        is-aabnormal nervous system regeneration +
                        is-aabnormal neuron physiology +
                        is-aabnormal neuronal stem cell physiology +
                        is-aabnormal pineal gland physiology +
                        is-aabnormal pituitary gland physiology +
                        is-aabnormal sensorimotor gating +
                        is-aabnormal somatic nervous system physiology +
                        is-aabnormal somatosensory cortex physiology +
                        is-aabnormal synaptic plasticity +
                        is-aabnormal synaptic transmission +
                        is-aaltered response to CNS ischemic injury +
                        is-aCNS inflammation +
                        is-aCNS ischemia
                        is-adecreased hindbrain apoptosis
                        is-aendoneurial edema
                        is-aincreased forebrain apoptosis
                        is-aincreased hindbrain apoptosis
                        is-aincreased midbrain apoptosis
                        is-aincreased neural tube apoptosis +
                        is-aincreased spinal cord apoptosis
                        is-aintracranial hemorrhage +
                        is-aseizures +
                        is-aspinal hemorrhage

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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory