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Mammalian Phenotype Browser
Term Detail
MP term:abnormal somite development
Synonym: abnormal metablastic segment development
Synonym: abnormal somite formation
Synonym: abnormal somite segmentation
Synonym: abnormal somitogenesis
MP id: MP:0001688
Definition: any anomaly in the formation of mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo; somites are transient structures - balls or blocks of paraxial mesoderm cells with an epithelial outer layer and a mesenchymal cell core - that emerge sequentially through a mesenchymal-to-epithelial transition (MET) from the morphologically unpatterned presomitic mesoderm; they give rise to the metameric anatomy of the vertebral column itself, and the associated skin, muscle and tendons
Number of paths to term: 1

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship


mammalian phenotype
        is-aembryogenesis phenotype
                is-aabnormal embryogenesis/ development
                        is-aabnormal embryonic tissue morphology
                                is-aabnormal anterior definitive endoderm morphology +
                                is-aabnormal cervical sinus morphology
                                is-aabnormal egg cylinder morphology +
                                is-aabnormal embryonic cloaca morphology +
                                is-aabnormal gastrula morphology
                                is-aabnormal gonadal ridge morphology +
                                is-aabnormal head fold morphology +
                                is-aabnormal head mesenchyme morphology +
                                is-aabnormal intraembryonic coelom morphology
                                is-aabnormal limb bud morphology +
                                is-aabnormal mesenchyme morphology +
                                is-aabnormal mesonephros morphology +
                                is-aabnormal neural fold morphology +
                                is-aabnormal neural plate morphology +
                                is-aabnormal neural tube morphology/development +
                                is-aabnormal notochord morphology +
                                is-aabnormal pharyngeal arch morphology +
                                is-aabnormal pharyngeal groove morphology
                                is-aabnormal pharyngeal membrane morphology
                                is-aabnormal pharyngeal pouch morphology +
                                is-aabnormal pleuropericardial membrane morphology +
                                is-aabnormal pluripotent precursor cell morphology/development +
                                is-aabnormal posterior definitive endoderm morphology
                                is-aabnormal rostral-caudal body axis extension
                                is-aabnormal septum transversum morphology
                                is-aabnormal somite development [MP:0001688] (388 genotypes, 529 annotations)
                                        is-aabnormal dorsal-ventral polarity of the somites
                                        is-aabnormal left-right axis symmetry of the somites
                                        is-aabnormal rostral-caudal patterning of the somites
                                        is-aabnormal somite border morphology
                                        is-aabnormal somite segmentation clock +
                                        is-aabnormal somite shape
                                        is-aabnormal somite size +
                                        is-adelayed somite formation
                                        is-afused somites
                                        is-aimpaired somite development +
                                        is-aincreased somite number
                                is-aabnormal tail bud morphology +
                                is-aabnormal tail fold morphology
                                is-aabnormal triploblastic development +
                                is-aabnormal urogenital fold morphology
                                is-aabnormal urorectal septum morphology
                                is-adisorganized embryonic tissue
                                is-aembryo tissue necrosis

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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory