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Mammalian Phenotype Browser
Term Detail
MP term:abnormal osteoclast physiology
Synonym: abnormal chondrocyte physiology
MP id: MP:0001541
Definition: any functional anomaly of the specialized phagocytic cells associated with the absorption and removal of the mineralized matrix of bone tissue
Number of paths to term: 9

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system physiology
                        is-aabnormal blood cell physiology
                                is-aabnormal leukocyte physiology
                                        is-aabnormal macrophage physiology
                                                is-aabnormal macrophage activation involved in immune response
                                                is-aabnormal macrophage antigen presentation +
                                                is-aabnormal macrophage apoptosis +
                                                is-aabnormal macrophage chemotaxis +
                                                is-aabnormal macrophage cytokine production +
                                                is-aabnormal macrophage nitric oxide production +
                                                is-aabnormal macrophage proliferation +
                                                is-aabnormal microglial cell physiology +
                                                is-aabnormal osteoclast physiology [MP:0001541] (95 genotypes, 95 annotations)
                                                is-aimpaired macrophage phagocytosis


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system physiology
                        is-aabnormal adaptive immunity
                                is-aabnormal leukocyte physiology
                                        is-aabnormal macrophage physiology
                                                is-aabnormal macrophage activation involved in immune response
                                                is-aabnormal macrophage antigen presentation +
                                                is-aabnormal macrophage apoptosis +
                                                is-aabnormal macrophage chemotaxis +
                                                is-aabnormal macrophage cytokine production +
                                                is-aabnormal macrophage nitric oxide production +
                                                is-aabnormal macrophage proliferation +
                                                is-aabnormal microglial cell physiology +
                                                is-aabnormal osteoclast physiology [MP:0001541] (95 genotypes, 95 annotations)
                                                is-aimpaired macrophage phagocytosis


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system physiology
                        is-aabnormal adaptive immunity
                                is-aabnormal professional antigen presenting cell physiology
                                        is-aabnormal macrophage physiology
                                                is-aabnormal macrophage activation involved in immune response
                                                is-aabnormal macrophage antigen presentation +
                                                is-aabnormal macrophage apoptosis +
                                                is-aabnormal macrophage chemotaxis +
                                                is-aabnormal macrophage cytokine production +
                                                is-aabnormal macrophage nitric oxide production +
                                                is-aabnormal macrophage proliferation +
                                                is-aabnormal microglial cell physiology +
                                                is-aabnormal osteoclast physiology [MP:0001541] (95 genotypes, 95 annotations)
                                                is-aimpaired macrophage phagocytosis


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system physiology
                        is-aabnormal cell-mediated immunity
                                is-aabnormal leukocyte physiology
                                        is-aabnormal macrophage physiology
                                                is-aabnormal macrophage activation involved in immune response
                                                is-aabnormal macrophage antigen presentation +
                                                is-aabnormal macrophage apoptosis +
                                                is-aabnormal macrophage chemotaxis +
                                                is-aabnormal macrophage cytokine production +
                                                is-aabnormal macrophage nitric oxide production +
                                                is-aabnormal macrophage proliferation +
                                                is-aabnormal microglial cell physiology +
                                                is-aabnormal osteoclast physiology [MP:0001541] (95 genotypes, 95 annotations)
                                                is-aimpaired macrophage phagocytosis


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system physiology
                        is-aabnormal cell-mediated immunity
                                is-aabnormal professional antigen presenting cell physiology
                                        is-aabnormal macrophage physiology
                                                is-aabnormal macrophage activation involved in immune response
                                                is-aabnormal macrophage antigen presentation +
                                                is-aabnormal macrophage apoptosis +
                                                is-aabnormal macrophage chemotaxis +
                                                is-aabnormal macrophage cytokine production +
                                                is-aabnormal macrophage nitric oxide production +
                                                is-aabnormal macrophage proliferation +
                                                is-aabnormal microglial cell physiology +
                                                is-aabnormal osteoclast physiology [MP:0001541] (95 genotypes, 95 annotations)
                                                is-aimpaired macrophage phagocytosis


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system physiology
                        is-aabnormal immune cell physiology
                                is-aabnormal leukocyte physiology
                                        is-aabnormal macrophage physiology
                                                is-aabnormal macrophage activation involved in immune response
                                                is-aabnormal macrophage antigen presentation +
                                                is-aabnormal macrophage apoptosis +
                                                is-aabnormal macrophage chemotaxis +
                                                is-aabnormal macrophage cytokine production +
                                                is-aabnormal macrophage nitric oxide production +
                                                is-aabnormal macrophage proliferation +
                                                is-aabnormal microglial cell physiology +
                                                is-aabnormal osteoclast physiology [MP:0001541] (95 genotypes, 95 annotations)
                                                is-aimpaired macrophage phagocytosis


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system physiology
                        is-aabnormal immune cell physiology
                                is-aabnormal professional antigen presenting cell physiology
                                        is-aabnormal macrophage physiology
                                                is-aabnormal macrophage activation involved in immune response
                                                is-aabnormal macrophage antigen presentation +
                                                is-aabnormal macrophage apoptosis +
                                                is-aabnormal macrophage chemotaxis +
                                                is-aabnormal macrophage cytokine production +
                                                is-aabnormal macrophage nitric oxide production +
                                                is-aabnormal macrophage proliferation +
                                                is-aabnormal microglial cell physiology +
                                                is-aabnormal osteoclast physiology [MP:0001541] (95 genotypes, 95 annotations)
                                                is-aimpaired macrophage phagocytosis


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system physiology
                        is-aabnormal innate immunity
                                is-aabnormal macrophage physiology
                                        is-aabnormal macrophage activation involved in immune response
                                        is-aabnormal macrophage antigen presentation +
                                        is-aabnormal macrophage apoptosis +
                                        is-aabnormal macrophage chemotaxis +
                                        is-aabnormal macrophage cytokine production +
                                        is-aabnormal macrophage nitric oxide production +
                                        is-aabnormal macrophage proliferation +
                                        is-aabnormal microglial cell physiology +
                                        is-aabnormal osteoclast physiology [MP:0001541] (95 genotypes, 95 annotations)
                                        is-aimpaired macrophage phagocytosis


mammalian phenotype
        is-askeleton phenotype
                is-aabnormal skeleton physiology
                        is-aabnormal bone remodeling
                                is-aabnormal bone resorption +
                                is-aabnormal ossification involved in bone remodeling
                                is-aabnormal osteoblast physiology
                                is-aabnormal osteoclast physiology [MP:0001541] (95 genotypes, 95 annotations)

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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory