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Mammalian Phenotype Browser
Term Detail
MP term:hyperkeratosis
Synonym: epidermal hyperkeratosis
Synonym: thickened cornified layer
Synonym: thickened horny layer
Synonym: thickened stratum corneum
Synonym: thicker cornified layer
Synonym: thicker horny layer
Synonym: thicker stratum corneum
MP id: MP:0001242
Alternate id: MP:0001223
Definition: increased depth of the corneal layer of the epidermis; thickening of the horny layer of the epidermis
Number of paths to term: 1

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship

mammalian phenotype
        is-aintegument phenotype
                is-aabnormal skin morphology
                        is-aabnormal epidermal layer morphology
                                is-aabnormal epidermis stratum corneum morphology
                                        is-aabnormal corneocyte envelope morphology +
                                        is-aabnormal stratum corneum lipid matrix formation
                                        is-aabsent epidermis stratum corneum
                                        is-ahyperkeratosis [MP:0001242] (209 genotypes, 244 annotations)
                                                is-aorthokeratosis
                                                is-aparakeratosis
                                        is-aimpaired stratum corneum desquamation
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Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Send questions and comments to User Support. 		last database update
05/08/2013
MGI 5.13 		The Jackson Laboratory