| MP term: | abnormal Purkinje cell morphology |
| Synonym: | abnormal Purkinje cells |
| Synonym: | abnormal Purkinje neuron morphology |
| MP id: | MP:0000877 |
| Definition: | any structural anomaly of the neurons located at the interface of the molecular and internal granule layers of the cerebellar cortex; these inhibitory neurons provide the output of the cerebellar cortex through axons that project into the white matter, and extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells |
| Number of paths to term: | 2 |
denotes an 'is-a' relationship
denotes a 'part-of' relationship
nervous system phenotypeabnormal nervous system morphologyabnormal brain morphologyabnormal hindbrain morphologyabnormal metencephalon morphologyabnormal cerebellum morphologyabnormal cerebellar cortex morphologyabnormal cerebellar layer morphologyabnormal cerebellar Purkinje cell layerabnormal Bergmann glial cell morphology +abnormal Purkinje cell morphology [MP:0000877] (353 genotypes, 486 annotations)abnormal Purkinje cell dendrite morphologyabnormal Purkinje cell differentiationabnormal Purkinje cell number +ectopic Purkinje cellPurkinje cell degenerationabsent Purkinje cell layerdelaminated Purkinje cell layernervous system phenotypeabnormal nervous system morphologyabnormal neuron morphologyabnormal adrenergic neuron morphologyabnormal Cajal-Retzius cell morphology +abnormal cerebral cortex pyramidal cell morphology +abnormal cholinergic neuron morphology +abnormal dopaminergic neuron morphology +abnormal enteric neuron morphology +abnormal GABAergic neuron morphology +abnormal glutaminergic neuron morphology +abnormal glycinergic neuron morphologyabnormal hippocampus neuron morphology +abnormal medium spiny neuron morphologyabnormal motor neuron morphology +abnormal neurite morphology +abnormal neuroendocrine cell morphology +abnormal neuron differentiation +abnormal neuron number +abnormal neuron specificationabnormal peptidergic neuron morphologyabnormal proprioceptive neuron morphology +abnormal Purkinje cell morphology [MP:0000877] (353 genotypes, 486 annotations)abnormal Purkinje cell dendrite morphologyabnormal Purkinje cell differentiationabnormal Purkinje cell number +ectopic Purkinje cellPurkinje cell degenerationabnormal sensory neuron morphology +abnormal serotonergic neuron morphologyabnormal synapse morphology +abnormal thalamus neuron morphologychromatolysisectopic neuron +neuron degeneration +neuron hypertrophyneuronal cytoplasmic inclusionsneuronal intranuclear inclusionsMouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc |
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last database update 05/08/2013 MGI 5.13 |
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