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Mammalian Phenotype Browser
Term Detail
MP term:Purkinje cell degeneration
MP id: MP:0000876
Definition: a retrogressive impairment of function or destruction of the large neurons located at the interface of the molecular and internal granule layers of the cerebellar cortex
Number of paths to term: 4

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship


mammalian phenotype
        is-anervous system phenotype
                is-aabnormal nervous system morphology
                        is-aabnormal brain morphology
                                is-aabnormal hindbrain morphology
                                        is-aabnormal metencephalon morphology
                                                is-aabnormal cerebellum morphology
                                                        is-aabnormal cerebellar cortex morphology
                                                                is-aabnormal cerebellar layer morphology
                                                                        is-aabnormal cerebellar Purkinje cell layer
                                                                                is-aabnormal Purkinje cell morphology
                                                                                        is-aabnormal Purkinje cell dendrite morphology
                                                                                        is-aabnormal Purkinje cell differentiation
                                                                                        is-aabnormal Purkinje cell number +
                                                                                        is-aectopic Purkinje cell
                                                                                        is-aPurkinje cell degeneration [MP:0000876] (128 genotypes, 128 annotations)
                                                                                                is-aPurkinje cell axonal dystrophy


mammalian phenotype
        is-anervous system phenotype
                is-aabnormal nervous system morphology
                        is-aabnormal neuron morphology
                                is-aabnormal Purkinje cell morphology
                                        is-aabnormal Purkinje cell dendrite morphology
                                        is-aabnormal Purkinje cell differentiation
                                        is-aabnormal Purkinje cell number +
                                        is-aectopic Purkinje cell
                                        is-aPurkinje cell degeneration [MP:0000876] (128 genotypes, 128 annotations)
                                                is-aPurkinje cell axonal dystrophy


mammalian phenotype
        is-anervous system phenotype
                is-aabnormal nervous system morphology
                        is-aabnormal neuron morphology
                                is-aneuron degeneration
                                        is-aamacrine cell degeneration
                                        is-acochlear hair cell degeneration +
                                        is-ahippocampal neuron degeneration
                                        is-amotor neuron degeneration
                                        is-aPurkinje cell degeneration [MP:0000876] (128 genotypes, 128 annotations)
                                                is-aPurkinje cell axonal dystrophy
                                        is-aretinal ganglion cell degeneration
                                        is-aretinal photoreceptor degeneration +
                                        is-avestibular hair cell degeneration


mammalian phenotype
        is-anervous system phenotype
                is-aabnormal nervous system morphology
                        is-aneurodegeneration
                                is-aneuron degeneration
                                        is-aamacrine cell degeneration
                                        is-acochlear hair cell degeneration +
                                        is-ahippocampal neuron degeneration
                                        is-amotor neuron degeneration
                                        is-aPurkinje cell degeneration [MP:0000876] (128 genotypes, 128 annotations)
                                                is-aPurkinje cell axonal dystrophy
                                        is-aretinal ganglion cell degeneration
                                        is-aretinal photoreceptor degeneration +
                                        is-avestibular hair cell degeneration

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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory