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Mammalian Phenotype Browser
Term Detail
MP term:abnormal substantia nigra morphology
Synonym: abnormal locus niger morphology
Synonym: abnormal nucleus niger morphology
Synonym: substantia nigra dysplasia
MP id: MP:0000836
Definition: any structural anomaly of the layer of grey substance that separates the posterior parts of the cerebral peduncles (tegmentum mesencephali) from the anterior parts; it normally includes a posterior compact part with many pigmented cells (pars compacta) and an anterior reticular part whose cells contain little pigment (pars reticularis)
Number of paths to term: 3

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship


mammalian phenotype
        is-anervous system phenotype
                is-aabnormal nervous system morphology
                        is-aabnormal brain morphology
                                is-aabnormal brainstem morphology
                                        is-aabnormal midbrain morphology
                                                is-aabnormal cerebral aqueduct morphology +
                                                is-aabnormal midbrain roof plate morphology +
                                                is-aabnormal midbrain size +
                                                is-aabnormal oculomotor nucleus morphology
                                                is-aabnormal pretectal region morphology +
                                                is-aabnormal substantia nigra morphology [MP:0000836] (37 genotypes, 40 annotations)
                                                        is-aabnormal substantia nigra pars compacta morphology
                                                        is-aabnormal substantia nigra pars reticulata morphology
                                                is-aabnormal tegmentum morphology +
                                                is-aabnormal trigeminal V mesencephalic nucleus morphology +
                                                is-aabsent midbrain
                                                is-amidbrain atrophy


mammalian phenotype
        is-anervous system phenotype
                is-aabnormal nervous system morphology
                        is-aabnormal brain morphology
                                is-aabnormal forebrain morphology
                                        is-aabnormal basal ganglion morphology
                                                is-aabnormal globus pallidus morphology
                                                is-aabnormal striatum morphology +
                                                is-aabnormal substantia nigra morphology [MP:0000836] (37 genotypes, 40 annotations)
                                                        is-aabnormal substantia nigra pars compacta morphology
                                                        is-aabnormal substantia nigra pars reticulata morphology
                                                is-aabnormal subthalamic nucleus morphology
                                                is-aloss of basal ganglia neurons


mammalian phenotype
        is-anervous system phenotype
                is-aabnormal nervous system morphology
                        is-aabnormal brain morphology
                                is-aabnormal midbrain morphology
                                        is-aabnormal cerebral aqueduct morphology +
                                        is-aabnormal midbrain roof plate morphology +
                                        is-aabnormal midbrain size +
                                        is-aabnormal oculomotor nucleus morphology
                                        is-aabnormal pretectal region morphology +
                                        is-aabnormal substantia nigra morphology [MP:0000836] (37 genotypes, 40 annotations)
                                                is-aabnormal substantia nigra pars compacta morphology
                                                is-aabnormal substantia nigra pars reticulata morphology
                                        is-aabnormal tegmentum morphology +
                                        is-aabnormal trigeminal V mesencephalic nucleus morphology +
                                        is-aabsent midbrain
                                        is-amidbrain atrophy

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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory