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Gene Ontology Browser
Term Detail
GO term:cellular response to acid chemical
Synonym: cellular response to acid
Synonym: cellular response to acid anion
Synonym: cellular response to oxoanion
GO id:GO:0071229
Definition:Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by the chemical structure of the anion portion of the dissociated acid (rather than the acid acting as a proton donor). The acid chemical may be in gaseous, liquid or solid form.
CommentsThis term should be used to describe a response to a specific acid as a chemical. E.g., if a cell were responding to glutamate, then the response would be glutamate-specific; the cell is actually responding to the chemical structure of the anion portion of the dissociated acid. Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. If annotating experiments where an acid is playing a role as a proton donor, please annotate to GO:0071468 'cellular response to acidic pH' instead.
Number of paths to term: 4

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-acellular response to stimulus
                                is-acellular response to chemical stimulus
                                        is-aactivation of SoxR protein
                                        is-acell chemotaxis +
                                        is-acellular response to acid chemical [GO:0071229] (191 genes, 202 annotations)
                                                is-acellular response to abscisic acid stimulus +
                                                is-acellular response to acetate
                                                is-acellular response to amino acid stimulus +
                                                is-acellular response to benzoic acid
                                                is-acellular response to bile acid
                                                is-acellular response to biotin
                                                is-acellular response to chlorate
                                                is-acellular response to fatty acid +
                                                is-acellular response to fluoride
                                                is-acellular response to gibberellin stimulus +
                                                is-acellular response to GW 7647
                                                is-acellular response to indolebutyric acid stimulus
                                                is-acellular response to jasmonic acid stimulus +
                                                is-acellular response to L-ascorbic acid
                                                is-acellular response to methanol
                                                is-acellular response to methotrexate
                                                is-acellular response to mycophenolic acid
                                                is-acellular response to nitrate
                                                is-acellular response to nitrite
                                                is-acellular response to ozone
                                                is-acellular response to retinoic acid
                                                is-acellular response to salicylic acid stimulus +
                                                is-acellular response to water stimulus +
                                                is-acellular stress response to acid chemical
                                        is-acellular response to alkane +
                                        is-acellular response to arsenic-containing substance +
                                        is-acellular response to boron-containing substance levels +
                                        is-acellular response to cisplatin
                                        is-acellular response to decane
                                        is-acellular response to dodecane
                                        is-acellular response to drug +
                                        is-acellular response to fluoride
                                        is-acellular response to food
                                        is-acellular response to inorganic substance +
                                        is-acellular response to isooctane
                                        is-acellular response to N-phenylthiourea
                                        is-acellular response to nitrogen compound +
                                        is-acellular response to nonane
                                        is-acellular response to nutrient +
                                        is-acellular response to organic substance +
                                        is-acellular response to oxidative stress +
                                        is-acellular response to oxygen levels +
                                        is-acellular response to oxygen-containing compound +
                                        is-acellular response to salt
                                        is-acellular response to tacrolimus
                                        is-acellular response to topoisomerase inhibitor
                                        is-acellular response to toxic substance +
                                        is-acellular response to undecane
                                        is-acellular response to xenobiotic stimulus +
                                        is-achemoattraction of axon +
                                        is-achemorepulsion of axon +
                                        is-adetection of hypoxic conditions in blood by chemoreceptor signaling +
                                        part-ofpositive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus +


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-acellular response to stimulus
                                is-acellular response to chemical stimulus
                                        is-aactivation of SoxR protein
                                        is-acell chemotaxis +
                                        is-acellular response to acid chemical [GO:0071229] (191 genes, 202 annotations)
                                                is-acellular response to abscisic acid stimulus +
                                                is-acellular response to acetate
                                                is-acellular response to amino acid stimulus +
                                                is-acellular response to benzoic acid
                                                is-acellular response to bile acid
                                                is-acellular response to biotin
                                                is-acellular response to chlorate
                                                is-acellular response to fatty acid +
                                                is-acellular response to fluoride
                                                is-acellular response to gibberellin stimulus +
                                                is-acellular response to GW 7647
                                                is-acellular response to indolebutyric acid stimulus
                                                is-acellular response to jasmonic acid stimulus +
                                                is-acellular response to L-ascorbic acid
                                                is-acellular response to methanol
                                                is-acellular response to methotrexate
                                                is-acellular response to mycophenolic acid
                                                is-acellular response to nitrate
                                                is-acellular response to nitrite
                                                is-acellular response to ozone
                                                is-acellular response to retinoic acid
                                                is-acellular response to salicylic acid stimulus +
                                                is-acellular response to water stimulus +
                                                is-acellular stress response to acid chemical
                                        is-acellular response to alkane +
                                        is-acellular response to arsenic-containing substance +
                                        is-acellular response to boron-containing substance levels +
                                        is-acellular response to cisplatin
                                        is-acellular response to decane
                                        is-acellular response to dodecane
                                        is-acellular response to drug +
                                        is-acellular response to fluoride
                                        is-acellular response to food
                                        is-acellular response to inorganic substance +
                                        is-acellular response to isooctane
                                        is-acellular response to N-phenylthiourea
                                        is-acellular response to nitrogen compound +
                                        is-acellular response to nonane
                                        is-acellular response to nutrient +
                                        is-acellular response to organic substance +
                                        is-acellular response to oxidative stress +
                                        is-acellular response to oxygen levels +
                                        is-acellular response to oxygen-containing compound +
                                        is-acellular response to salt
                                        is-acellular response to tacrolimus
                                        is-acellular response to topoisomerase inhibitor
                                        is-acellular response to toxic substance +
                                        is-acellular response to undecane
                                        is-acellular response to xenobiotic stimulus +
                                        is-achemoattraction of axon +
                                        is-achemorepulsion of axon +
                                        is-adetection of hypoxic conditions in blood by chemoreceptor signaling +
                                        part-ofpositive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus +


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-aresponse to chemical
                                is-acellular response to chemical stimulus
                                        is-aactivation of SoxR protein
                                        is-acell chemotaxis +
                                        is-acellular response to acid chemical [GO:0071229] (191 genes, 202 annotations)
                                                is-acellular response to abscisic acid stimulus +
                                                is-acellular response to acetate
                                                is-acellular response to amino acid stimulus +
                                                is-acellular response to benzoic acid
                                                is-acellular response to bile acid
                                                is-acellular response to biotin
                                                is-acellular response to chlorate
                                                is-acellular response to fatty acid +
                                                is-acellular response to fluoride
                                                is-acellular response to gibberellin stimulus +
                                                is-acellular response to GW 7647
                                                is-acellular response to indolebutyric acid stimulus
                                                is-acellular response to jasmonic acid stimulus +
                                                is-acellular response to L-ascorbic acid
                                                is-acellular response to methanol
                                                is-acellular response to methotrexate
                                                is-acellular response to mycophenolic acid
                                                is-acellular response to nitrate
                                                is-acellular response to nitrite
                                                is-acellular response to ozone
                                                is-acellular response to retinoic acid
                                                is-acellular response to salicylic acid stimulus +
                                                is-acellular response to water stimulus +
                                                is-acellular stress response to acid chemical
                                        is-acellular response to alkane +
                                        is-acellular response to arsenic-containing substance +
                                        is-acellular response to boron-containing substance levels +
                                        is-acellular response to cisplatin
                                        is-acellular response to decane
                                        is-acellular response to dodecane
                                        is-acellular response to drug +
                                        is-acellular response to fluoride
                                        is-acellular response to food
                                        is-acellular response to inorganic substance +
                                        is-acellular response to isooctane
                                        is-acellular response to N-phenylthiourea
                                        is-acellular response to nitrogen compound +
                                        is-acellular response to nonane
                                        is-acellular response to nutrient +
                                        is-acellular response to organic substance +
                                        is-acellular response to oxidative stress +
                                        is-acellular response to oxygen levels +
                                        is-acellular response to oxygen-containing compound +
                                        is-acellular response to salt
                                        is-acellular response to tacrolimus
                                        is-acellular response to topoisomerase inhibitor
                                        is-acellular response to toxic substance +
                                        is-acellular response to undecane
                                        is-acellular response to xenobiotic stimulus +
                                        is-achemoattraction of axon +
                                        is-achemorepulsion of axon +
                                        is-adetection of hypoxic conditions in blood by chemoreceptor signaling +
                                        part-ofpositive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus +


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-aresponse to chemical
                                is-aresponse to acid chemical
                                        is-acellular response to acid chemical [GO:0071229] (191 genes, 202 annotations)
                                                is-acellular response to abscisic acid stimulus +
                                                is-acellular response to acetate
                                                is-acellular response to amino acid stimulus +
                                                is-acellular response to benzoic acid
                                                is-acellular response to bile acid
                                                is-acellular response to biotin
                                                is-acellular response to chlorate
                                                is-acellular response to fatty acid +
                                                is-acellular response to fluoride
                                                is-acellular response to gibberellin stimulus +
                                                is-acellular response to GW 7647
                                                is-acellular response to indolebutyric acid stimulus
                                                is-acellular response to jasmonic acid stimulus +
                                                is-acellular response to L-ascorbic acid
                                                is-acellular response to methanol
                                                is-acellular response to methotrexate
                                                is-acellular response to mycophenolic acid
                                                is-acellular response to nitrate
                                                is-acellular response to nitrite
                                                is-acellular response to ozone
                                                is-acellular response to retinoic acid
                                                is-acellular response to salicylic acid stimulus +
                                                is-acellular response to water stimulus +
                                                is-acellular stress response to acid chemical
                                        is-aresponse to abscisic acid +
                                        is-aresponse to acetate +
                                        is-aresponse to acetylsalicylate
                                        is-aresponse to amino acid +
                                        is-aresponse to benzoic acid +
                                        is-aresponse to bile acid +
                                        is-aresponse to biotin +
                                        is-aresponse to butan-1-ol +
                                        is-aresponse to candesartan
                                        is-aresponse to chlorate +
                                        is-aresponse to fatty acid +
                                        is-aresponse to fluoride +
                                        is-aresponse to formic acid +
                                        is-aresponse to gibberellin +
                                        is-aresponse to GW 7647 +
                                        is-aresponse to hypochlorite
                                        is-aresponse to indolebutyric acid +
                                        is-aresponse to jasmonic acid +
                                        is-aresponse to L-ascorbic acid +
                                        is-aresponse to methanol +
                                        is-aresponse to methotrexate +
                                        is-aresponse to mycophenolic acid +
                                        is-aresponse to nitrate +
                                        is-aresponse to nitrite +
                                        is-aresponse to ozone +
                                        is-aresponse to propan-1-ol +
                                        is-aresponse to retinoic acid +
                                        is-aresponse to salicylic acid +
                                        is-aresponse to water +
                                        is-astress response to acid chemical +


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last database update
11/18/2014
MGI 5.20
The Jackson Laboratory