About   Help   FAQ
Gene Ontology Browser
Term Detail
GO term:neuron death
Synonym: neuronal cell death
Synonym: neuron cell death
GO id:GO:0070997
Definition:The process of cell death in a neuron.
CommentsThis term should not be used for direct annotation. The only exception should be when experimental data (e.g., staining with trypan blue or propidium iodide or use of neuron-specific markers) show that neuron death has occurred, but fail to provide details on death modality (accidental versus programmed). When information is provided on the neuron death mechanism, annotations should be made to the appropriate descendant of 'cell death' (such as, but not limited to, GO:0097300 'programmed necrotic cell death' or GO:0006915 'apoptotic process'), and the cell type captured as an annotation extension; or the term GO:0051402 'neuron apoptotic process' may be considered, if appropriate.
Number of paths to term: 3

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-acell death
                                        is-acell death in response to oxidative stress +
                                        is-anecrotic cell death +
                                        negatively-regulatesnegative regulation of cell death +
                                        is-aneuron death [GO:0070997] (293 genes, 409 annotations)
                                                negatively-regulatesnegative regulation of neuron death +
                                                is-aneuron apoptotic process +
                                                is-aneuron death in response to oxidative stress +
                                                positively-regulatespositive regulation of neuron death +
                                                regulatesregulation of neuron death +
                                        positively-regulatespositive regulation of cell death +
                                        is-aprogrammed cell death +
                                        regulatesregulation of cell death +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-adeath
                                is-acell death
                                        is-acell death in response to oxidative stress +
                                        is-anecrotic cell death +
                                        negatively-regulatesnegative regulation of cell death +
                                        is-aneuron death [GO:0070997] (293 genes, 409 annotations)
                                                negatively-regulatesnegative regulation of neuron death +
                                                is-aneuron apoptotic process +
                                                is-aneuron death in response to oxidative stress +
                                                positively-regulatespositive regulation of neuron death +
                                                regulatesregulation of neuron death +
                                        positively-regulatespositive regulation of cell death +
                                        is-aprogrammed cell death +
                                        regulatesregulation of cell death +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-acell death
                                        is-acell death in response to oxidative stress +
                                        is-anecrotic cell death +
                                        negatively-regulatesnegative regulation of cell death +
                                        is-aneuron death [GO:0070997] (293 genes, 409 annotations)
                                                negatively-regulatesnegative regulation of neuron death +
                                                is-aneuron apoptotic process +
                                                is-aneuron death in response to oxidative stress +
                                                positively-regulatespositive regulation of neuron death +
                                                regulatesregulation of neuron death +
                                        positively-regulatespositive regulation of cell death +
                                        is-aprogrammed cell death +
                                        regulatesregulation of cell death +


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
10/08/2014
MGI 5.20
The Jackson Laboratory