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Gene Ontology Browser
Term Detail
GO term:regulation of inhibitory postsynaptic membrane potential
Synonym: IPSP
Synonym: regulation of inhibitory post-synaptic membrane potential
GO id:GO:0060080
Definition:Any process that modulates the establishment or extent of the inhibitory postsynaptic potential (IPSP) which is a temporary decrease in postsynaptic membrane potential due to the flow of negatively charged ions into the postsynaptic cell. The flow of ions that causes an IPSP is an inhibitory postsynaptic current (IPSC) and makes it more difficult for the neuron to fire an action potential.
Number of paths to term: 7

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological quality
                                is-aregulation of membrane potential
                                        is-amembrane hyperpolarization
                                                negatively-regulatesnegative regulation of membrane hyperpolarization
                                                positively-regulatespositive regulation of membrane hyperpolarization
                                                is-aregulation of inhibitory postsynaptic membrane potential [GO:0060080] (12 genes, 16 annotations)
                                                        is-apositive regulation of inhibitory postsynaptic membrane potential
                                                regulatesregulation of membrane hyperpolarization +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological quality
                                is-aregulation of membrane potential
                                        is-aregulation of postsynaptic membrane potential
                                                is-aregulation of excitatory postsynaptic membrane potential +
                                                is-aregulation of inhibitory postsynaptic membrane potential [GO:0060080] (12 genes, 16 annotations)
                                                        is-apositive regulation of inhibitory postsynaptic membrane potential


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-acell communication
                                        is-acell-cell signaling
                                                is-asynaptic transmission
                                                        part-ofregulation of postsynaptic membrane potential
                                                                is-aregulation of excitatory postsynaptic membrane potential +
                                                                is-aregulation of inhibitory postsynaptic membrane potential [GO:0060080] (12 genes, 16 annotations)
                                                                        is-apositive regulation of inhibitory postsynaptic membrane potential


Gene_Ontology
        is-abiological_process
                is-asignaling
                        is-asingle organism signaling
                                is-acell-cell signaling
                                        is-asynaptic transmission
                                                part-ofregulation of postsynaptic membrane potential
                                                        is-aregulation of excitatory postsynaptic membrane potential +
                                                        is-aregulation of inhibitory postsynaptic membrane potential [GO:0060080] (12 genes, 16 annotations)
                                                                is-apositive regulation of inhibitory postsynaptic membrane potential


Gene_Ontology
        is-abiological_process
                is-asignaling
                        is-asynaptic transmission
                                part-ofregulation of postsynaptic membrane potential
                                        is-aregulation of excitatory postsynaptic membrane potential +
                                        is-aregulation of inhibitory postsynaptic membrane potential [GO:0060080] (12 genes, 16 annotations)
                                                is-apositive regulation of inhibitory postsynaptic membrane potential


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle organism signaling
                                is-acell-cell signaling
                                        is-asynaptic transmission
                                                part-ofregulation of postsynaptic membrane potential
                                                        is-aregulation of excitatory postsynaptic membrane potential +
                                                        is-aregulation of inhibitory postsynaptic membrane potential [GO:0060080] (12 genes, 16 annotations)
                                                                is-apositive regulation of inhibitory postsynaptic membrane potential


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-acell communication
                                        is-acell-cell signaling
                                                is-asynaptic transmission
                                                        part-ofregulation of postsynaptic membrane potential
                                                                is-aregulation of excitatory postsynaptic membrane potential +
                                                                is-aregulation of inhibitory postsynaptic membrane potential [GO:0060080] (12 genes, 16 annotations)
                                                                        is-apositive regulation of inhibitory postsynaptic membrane potential


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory