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Gene Ontology Browser
Term Detail
GO term:cholestenone 5-alpha-reductase activity
Synonym: 3-oxo-5alpha-steroid:NADP+ delta4-oxidoreductase activity
Synonym: 3-oxosteroid 5alpha-reductase activity
Synonym: 3-oxosteroid delta4-dehydrogenase
Synonym: 4-ene-3-oxosteroid 5alpha-reductase activity
Synonym: 4-ene-5alpha-reductase activity
Synonym: 5alpha-reductase
Synonym: cholest-4-en-3-one 5alpha-reductase activity
Synonym: cholestenone 5alpha-reductase activity
Synonym: cholestenone 5a-reductase activity
Synonym: delta4-3-ketosteroid 5alpha-oxidoreductase activity
Synonym: reduced nicotinamide adenine dinucleotide phosphate:Delta4-3-ketosteroid 5alpha-oxidoreductase activity
Synonym: steroid 5alpha-hydrogenase activity
Synonym: steroid 5alpha-reductase
Synonym: testosterone 5alpha-reductase
Synonym: testosterone delta4-5alpha-reductase activity
Synonym: testosterone delta4-hydrogenase activity
GO id:GO:0047751
Definition:Catalysis of the reaction: 5alpha-cholestan-3-one + NADP(+) = cholest-4-en-3-one + H(+) + NADPH.
Number of paths to term: 1

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-amolecular_function
                is-acatalytic activity
                        is-aoxidoreductase activity
                                is-aoxidoreductase activity, acting on the CH-CH group of donors
                                        is-aoxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
                                                is-aenone reductase activity
                                                        is-a(-)-isopiperitenone reductase activity
                                                        is-a3-oxo-delta(4,5)-steroid 5-beta-reductase activity
                                                        is-acholestenone 5-alpha-reductase activity [GO:0047751] (3 genes, 3 annotations)
                                                        is-adelta4-3-oxosteroid 5beta-reductase activity


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory