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Term Detail
GO term:negative regulation of G-protein coupled receptor protein signaling pathway
Synonym: down regulation of G-protein coupled receptor protein signaling pathway
Synonym: down-regulation of G-protein coupled receptor protein signaling pathway
Synonym: downregulation of G-protein coupled receptor protein signaling pathway
Synonym: inhibition of G-protein coupled receptor protein signaling pathway
Synonym: negative regulation of GPCR protein signaling pathway
Synonym: negative regulation of GPCR protein signalling pathway
Synonym: negative regulation of G protein coupled receptor protein signaling pathway
Synonym: negative regulation of G-protein-coupled receptor protein signaling pathway
Synonym: negative regulation of G protein coupled receptor protein signalling pathway
Synonym: negative regulation of G-protein coupled receptor protein signalling pathway
Synonym: negative regulation of G-protein-coupled receptor protein signalling pathway
GO id:GO:0045744
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of G-protein coupled receptor protein signaling pathway activity.
Number of paths to term: 99

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-anegative regulation of biological process
                                        is-anegative regulation of cellular process
                                                is-anegative regulation of cell communication
                                                        is-anegative regulation of signal transduction
                                                                is-aextracellular negative regulation of signal transduction +
                                                                is-ametarhodopsin inactivation
                                                                is-anegative adaptation of signaling pathway +
                                                                is-anegative regulation by symbiont of host cAMP-mediated signal transduction +
                                                                is-anegative regulation by symbiont of host salicylic acid-mediated defense response +
                                                                is-anegative regulation of abscisic acid-activated signaling pathway
                                                                is-anegative regulation of anti-Mullerian hormone signaling pathway
                                                                is-anegative regulation of antigen receptor-mediated signaling pathway +
                                                                is-anegative regulation of apoptotic signaling pathway +
                                                                is-anegative regulation of auxin mediated signaling pathway
                                                                is-anegative regulation of brain-derived neurotrophic factor receptor signaling pathway +
                                                                is-anegative regulation of brassinosteroid mediated signaling pathway
                                                                is-anegative regulation of CD40 signaling pathway
                                                                is-anegative regulation of cytokine-mediated signaling pathway +
                                                                is-anegative regulation of cytokinin-activated signaling pathway
                                                                is-anegative regulation of endoplasmic reticulum unfolded protein response
                                                                is-anegative regulation of ephrin receptor signaling pathway
                                                                is-anegative regulation of ERBB signaling pathway +
                                                                is-anegative regulation of Fas signaling pathway
                                                                is-anegative regulation of fibroblast growth factor receptor signaling pathway +
                                                                is-anegative regulation of G-protein coupled receptor protein signaling pathway [GO:0045744] (61 genes, 82 annotations)
                                                                        is-adesensitization of G-protein coupled receptor protein signaling pathway +
                                                                        is-aG-protein coupled receptor catabolic process
                                                                        is-anegative regulation by host of symbiont G-protein coupled receptor protein signal transduction +
                                                                        is-anegative regulation by symbiont of host G-protein coupled receptor protein signal transduction +
                                                                        is-anegative regulation of adenosine receptor signaling pathway
                                                                        is-anegative regulation of adrenergic receptor signaling pathway +
                                                                        is-anegative regulation of dopamine receptor signaling pathway +
                                                                        is-anegative regulation of G-protein coupled receptor protein signaling pathway in response to host +
                                                                        is-anegative regulation of octopamine or tyramine signaling pathway +
                                                                        is-anegative regulation of opioid receptor signaling pathway +
                                                                        is-anegative regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion
                                                                        is-anegative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway +
                                                                        is-anegative regulation of thrombin receptor signaling pathway
                                                                        is-atermination of G-protein coupled receptor signaling pathway
                                                                is-anegative regulation of gibberellic acid mediated signaling pathway
                                                                is-anegative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation
                                                                is-anegative regulation of glucocorticoid mediated signaling pathway
                                                                is-anegative regulation of glucose mediated signaling pathway
                                                                is-anegative regulation of glutamate receptor signaling pathway
                                                                is-anegative regulation of growth hormone receptor signaling pathway
                                                                is-anegative regulation of hepatocyte growth factor receptor signaling pathway
                                                                is-anegative regulation of hypoxia-inducible factor-1alpha signaling pathway
                                                                is-anegative regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
                                                                is-anegative regulation of insulin receptor signaling pathway +
                                                                is-anegative regulation of insulin-like growth factor receptor signaling pathway
                                                                is-anegative regulation of integrin-mediated signaling pathway
                                                                is-anegative regulation of intracellular signal transduction +
                                                                is-anegative regulation of intracellular steroid hormone receptor signaling pathway +
                                                                is-anegative regulation of lipopolysaccharide-mediated signaling pathway +
                                                                is-anegative regulation of nerve growth factor receptor activity
                                                                is-anegative regulation of netrin-activated signaling pathway
                                                                is-anegative regulation of neuronal signal transduction
                                                                is-anegative regulation of neurotrophin TRK receptor signaling pathway
                                                                is-anegative regulation of Notch signaling pathway +
                                                                is-anegative regulation of peptidoglycan recognition protein signaling pathway
                                                                is-anegative regulation of peroxisome proliferator activated receptor signaling pathway
                                                                is-anegative regulation of phosphorelay signal transduction system +
                                                                is-anegative regulation of platelet-derived growth factor receptor signaling pathway +
                                                                is-anegative regulation of red or far-red light signaling pathway
                                                                is-anegative regulation of retinoic acid receptor signaling pathway
                                                                is-anegative regulation of Roundabout signaling pathway +
                                                                is-anegative regulation of semaphorin-plexin signaling pathway
                                                                is-anegative regulation of sevenless signaling pathway
                                                                is-anegative regulation of signal transduction by receptor internalization +
                                                                is-anegative regulation of signal transduction in absence of ligand +
                                                                is-anegative regulation of signal transduction in response to host +
                                                                is-anegative regulation of signal transduction involved in conjugation with cellular fusion +
                                                                is-anegative regulation of smoothened signaling pathway +
                                                                is-anegative regulation of sphingolipid mediated signaling pathway
                                                                is-anegative regulation of SREBP signaling pathway +
                                                                is-anegative regulation of thyroid hormone mediated signaling pathway
                                                                is-anegative regulation of Toll signaling pathway
                                                                is-anegative regulation of toll-like receptor signaling pathway +
                                                                is-anegative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                                is-anegative regulation of vascular endothelial growth factor receptor signaling pathway
                                                                is-anegative regulation of vascular endothelial growth factor signaling pathway
                                                                is-anegative regulation of vitamin D receptor signaling pathway
                                                                is-anegative regulation of Wnt signaling pathway +
                                                                is-atermination of signal transduction +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-anegative regulation of biological process
                                        is-anegative regulation of response to stimulus
                                                is-anegative regulation of signal transduction
                                                        is-aextracellular negative regulation of signal transduction +
                                                        is-ametarhodopsin inactivation
                                                        is-anegative adaptation of signaling pathway +
                                                        is-anegative regulation by symbiont of host cAMP-mediated signal transduction +
                                                        is-anegative regulation by symbiont of host salicylic acid-mediated defense response +
                                                        is-anegative regulation of abscisic acid-activated signaling pathway
                                                        is-anegative regulation of anti-Mullerian hormone signaling pathway
                                                        is-anegative regulation of antigen receptor-mediated signaling pathway +
                                                        is-anegative regulation of apoptotic signaling pathway +
                                                        is-anegative regulation of auxin mediated signaling pathway
                                                        is-anegative regulation of brain-derived neurotrophic factor receptor signaling pathway +
                                                        is-anegative regulation of brassinosteroid mediated signaling pathway
                                                        is-anegative regulation of CD40 signaling pathway
                                                        is-anegative regulation of cytokine-mediated signaling pathway +
                                                        is-anegative regulation of cytokinin-activated signaling pathway
                                                        is-anegative regulation of endoplasmic reticulum unfolded protein response
                                                        is-anegative regulation of ephrin receptor signaling pathway
                                                        is-anegative regulation of ERBB signaling pathway +
                                                        is-anegative regulation of Fas signaling pathway
                                                        is-anegative regulation of fibroblast growth factor receptor signaling pathway +
                                                        is-anegative regulation of G-protein coupled receptor protein signaling pathway [GO:0045744] (61 genes, 82 annotations)
                                                                is-adesensitization of G-protein coupled receptor protein signaling pathway +
                                                                is-aG-protein coupled receptor catabolic process
                                                                is-anegative regulation by host of symbiont G-protein coupled receptor protein signal transduction +
                                                                is-anegative regulation by symbiont of host G-protein coupled receptor protein signal transduction +
                                                                is-anegative regulation of adenosine receptor signaling pathway
                                                                is-anegative regulation of adrenergic receptor signaling pathway +
                                                                is-anegative regulation of dopamine receptor signaling pathway +
                                                                is-anegative regulation of G-protein coupled receptor protein signaling pathway in response to host +
                                                                is-anegative regulation of octopamine or tyramine signaling pathway +
                                                                is-anegative regulation of opioid receptor signaling pathway +
                                                                is-anegative regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion
                                                                is-anegative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway +
                                                                is-anegative regulation of thrombin receptor signaling pathway
                                                                is-atermination of G-protein coupled receptor signaling pathway
                                                        is-anegative regulation of gibberellic acid mediated signaling pathway
                                                        is-anegative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation
                                                        is-anegative regulation of glucocorticoid mediated signaling pathway
                                                        is-anegative regulation of glucose mediated signaling pathway
                                                        is-anegative regulation of glutamate receptor signaling pathway
                                                        is-anegative regulation of growth hormone receptor signaling pathway
                                                        is-anegative regulation of hepatocyte growth factor receptor signaling pathway
                                                        is-anegative regulation of hypoxia-inducible factor-1alpha signaling pathway
                                                        is-anegative regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
                                                        is-anegative regulation of insulin receptor signaling pathway +
                                                        is-anegative regulation of insulin-like growth factor receptor signaling pathway
                                                        is-anegative regulation of integrin-mediated signaling pathway
                                                        is-anegative regulation of intracellular signal transduction +
                                                        is-anegative regulation of intracellular steroid hormone receptor signaling pathway +
                                                        is-anegative regulation of lipopolysaccharide-mediated signaling pathway +
                                                        is-anegative regulation of nerve growth factor receptor activity
                                                        is-anegative regulation of netrin-activated signaling pathway
                                                        is-anegative regulation of neuronal signal transduction
                                                        is-anegative regulation of neurotrophin TRK receptor signaling pathway
                                                        is-anegative regulation of Notch signaling pathway +
                                                        is-anegative regulation of peptidoglycan recognition protein signaling pathway
                                                        is-anegative regulation of peroxisome proliferator activated receptor signaling pathway
                                                        is-anegative regulation of phosphorelay signal transduction system +
                                                        is-anegative regulation of platelet-derived growth factor receptor signaling pathway +
                                                        is-anegative regulation of red or far-red light signaling pathway
                                                        is-anegative regulation of retinoic acid receptor signaling pathway
                                                        is-anegative regulation of Roundabout signaling pathway +
                                                        is-anegative regulation of semaphorin-plexin signaling pathway
                                                        is-anegative regulation of sevenless signaling pathway
                                                        is-anegative regulation of signal transduction by receptor internalization +
                                                        is-anegative regulation of signal transduction in absence of ligand +
                                                        is-anegative regulation of signal transduction in response to host +
                                                        is-anegative regulation of signal transduction involved in conjugation with cellular fusion +
                                                        is-anegative regulation of smoothened signaling pathway +
                                                        is-anegative regulation of sphingolipid mediated signaling pathway
                                                        is-anegative regulation of SREBP signaling pathway +
                                                        is-anegative regulation of thyroid hormone mediated signaling pathway
                                                        is-anegative regulation of Toll signaling pathway
                                                        is-anegative regulation of toll-like receptor signaling pathway +
                                                        is-anegative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                        is-anegative regulation of vascular endothelial growth factor receptor signaling pathway
                                                        is-anegative regulation of vascular endothelial growth factor signaling pathway
                                                        is-anegative regulation of vitamin D receptor signaling pathway
                                                        is-anegative regulation of Wnt signaling pathway +
                                                        is-atermination of signal transduction +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-anegative regulation of biological process
                                        is-anegative regulation of signaling
                                                is-anegative regulation of signal transduction
                                                        is-aextracellular negative regulation of signal transduction +
                                                        is-ametarhodopsin inactivation
                                                        is-anegative adaptation of signaling pathway +
                                                        is-anegative regulation by symbiont of host cAMP-mediated signal transduction +
                                                        is-anegative regulation by symbiont of host salicylic acid-mediated defense response +
                                                        is-anegative regulation of abscisic acid-activated signaling pathway
                                                        is-anegative regulation of anti-Mullerian hormone signaling pathway
                                                        is-anegative regulation of antigen receptor-mediated signaling pathway +
                                                        is-anegative regulation of apoptotic signaling pathway +
                                                        is-anegative regulation of auxin mediated signaling pathway
                                                        is-anegative regulation of brain-derived neurotrophic factor receptor signaling pathway +
                                                        is-anegative regulation of brassinosteroid mediated signaling pathway
                                                        is-anegative regulation of CD40 signaling pathway
                                                        is-anegative regulation of cytokine-mediated signaling pathway +
                                                        is-anegative regulation of cytokinin-activated signaling pathway
                                                        is-anegative regulation of endoplasmic reticulum unfolded protein response
                                                        is-anegative regulation of ephrin receptor signaling pathway
                                                        is-anegative regulation of ERBB signaling pathway +
                                                        is-anegative regulation of Fas signaling pathway
                                                        is-anegative regulation of fibroblast growth factor receptor signaling pathway +
                                                        is-anegative regulation of G-protein coupled receptor protein signaling pathway [GO:0045744] (61 genes, 82 annotations)
                                                                is-adesensitization of G-protein coupled receptor protein signaling pathway +
                                                                is-aG-protein coupled receptor catabolic process
                                                                is-anegative regulation by host of symbiont G-protein coupled receptor protein signal transduction +
                                                                is-anegative regulation by symbiont of host G-protein coupled receptor protein signal transduction +
                                                                is-anegative regulation of adenosine receptor signaling pathway
                                                                is-anegative regulation of adrenergic receptor signaling pathway +
                                                                is-anegative regulation of dopamine receptor signaling pathway +
                                                                is-anegative regulation of G-protein coupled receptor protein signaling pathway in response to host +
                                                                is-anegative regulation of octopamine or tyramine signaling pathway +
                                                                is-anegative regulation of opioid receptor signaling pathway +
                                                                is-anegative regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion
                                                                is-anegative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway +
                                                                is-anegative regulation of thrombin receptor signaling pathway
                                                                is-atermination of G-protein coupled receptor signaling pathway
                                                        is-anegative regulation of gibberellic acid mediated signaling pathway
                                                        is-anegative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation
                                                        is-anegative regulation of glucocorticoid mediated signaling pathway
                                                        is-anegative regulation of glucose mediated signaling pathway
                                                        is-anegative regulation of glutamate receptor signaling pathway
                                                        is-anegative regulation of growth hormone receptor signaling pathway
                                                        is-anegative regulation of hepatocyte growth factor receptor signaling pathway
                                                        is-anegative regulation of hypoxia-inducible factor-1alpha signaling pathway
                                                        is-anegative regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
                                                        is-anegative regulation of insulin receptor signaling pathway +
                                                        is-anegative regulation of insulin-like growth factor receptor signaling pathway
                                                        is-anegative regulation of integrin-mediated signaling pathway
                                                        is-anegative regulation of intracellular signal transduction +
                                                        is-anegative regulation of intracellular steroid hormone receptor signaling pathway +
                                                        is-anegative regulation of lipopolysaccharide-mediated signaling pathway +
                                                        is-anegative regulation of nerve growth factor receptor activity
                                                        is-anegative regulation of netrin-activated signaling pathway
                                                        is-anegative regulation of neuronal signal transduction
                                                        is-anegative regulation of neurotrophin TRK receptor signaling pathway
                                                        is-anegative regulation of Notch signaling pathway +
                                                        is-anegative regulation of peptidoglycan recognition protein signaling pathway
                                                        is-anegative regulation of peroxisome proliferator activated receptor signaling pathway
                                                        is-anegative regulation of phosphorelay signal transduction system +
                                                        is-anegative regulation of platelet-derived growth factor receptor signaling pathway +
                                                        is-anegative regulation of red or far-red light signaling pathway
                                                        is-anegative regulation of retinoic acid receptor signaling pathway
                                                        is-anegative regulation of Roundabout signaling pathway +
                                                        is-anegative regulation of semaphorin-plexin signaling pathway
                                                        is-anegative regulation of sevenless signaling pathway
                                                        is-anegative regulation of signal transduction by receptor internalization +
                                                        is-anegative regulation of signal transduction in absence of ligand +
                                                        is-anegative regulation of signal transduction in response to host +
                                                        is-anegative regulation of signal transduction involved in conjugation with cellular fusion +
                                                        is-anegative regulation of smoothened signaling pathway +
                                                        is-anegative regulation of sphingolipid mediated signaling pathway
                                                        is-anegative regulation of SREBP signaling pathway +
                                                        is-anegative regulation of thyroid hormone mediated signaling pathway
                                                        is-anegative regulation of Toll signaling pathway
                                                        is-anegative regulation of toll-like receptor signaling pathway +
                                                        is-anegative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                        is-anegative regulation of vascular endothelial growth factor receptor signaling pathway
                                                        is-anegative regulation of vascular endothelial growth factor signaling pathway
                                                        is-anegative regulation of vitamin D receptor signaling pathway
                                                        is-anegative regulation of Wnt signaling pathway +
                                                        is-atermination of signal transduction +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-anegative regulation of cellular process
                                                is-anegative regulation of cell communication
                                                        is-anegative regulation of signal transduction
                                                                is-aextracellular negative regulation of signal transduction +
                                                                is-ametarhodopsin inactivation
                                                                is-anegative adaptation of signaling pathway +
                                                                is-anegative regulation by symbiont of host cAMP-mediated signal transduction +
                                                                is-anegative regulation by symbiont of host salicylic acid-mediated defense response +
                                                                is-anegative regulation of abscisic acid-activated signaling pathway
                                                                is-anegative regulation of anti-Mullerian hormone signaling pathway
                                                                is-anegative regulation of antigen receptor-mediated signaling pathway +
                                                                is-anegative regulation of apoptotic signaling pathway +
                                                                is-anegative regulation of auxin mediated signaling pathway
                                                                is-anegative regulation of brain-derived neurotrophic factor receptor signaling pathway +
                                                                is-anegative regulation of brassinosteroid mediated signaling pathway
                                                                is-anegative regulation of CD40 signaling pathway
                                                                is-anegative regulation of cytokine-mediated signaling pathway +
                                                                is-anegative regulation of cytokinin-activated signaling pathway
                                                                is-anegative regulation of endoplasmic reticulum unfolded protein response
                                                                is-anegative regulation of ephrin receptor signaling pathway
                                                                is-anegative regulation of ERBB signaling pathway +
                                                                is-anegative regulation of Fas signaling pathway
                                                                is-anegative regulation of fibroblast growth factor receptor signaling pathway +
                                                                is-anegative regulation of G-protein coupled receptor protein signaling pathway [GO:0045744] (61 genes, 82 annotations)
                                                                        is-adesensitization of G-protein coupled receptor protein signaling pathway +
                                                                        is-aG-protein coupled receptor catabolic process
                                                                        is-anegative regulation by host of symbiont G-protein coupled receptor protein signal transduction +
                                                                        is-anegative regulation by symbiont of host G-protein coupled receptor protein signal transduction +
                                                                        is-anegative regulation of adenosine receptor signaling pathway
                                                                        is-anegative regulation of adrenergic receptor signaling pathway +
                                                                        is-anegative regulation of dopamine receptor signaling pathway +
                                                                        is-anegative regulation of G-protein coupled receptor protein signaling pathway in response to host +
                                                                        is-anegative regulation of octopamine or tyramine signaling pathway +
                                                                        is-anegative regulation of opioid receptor signaling pathway +
                                                                        is-anegative regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion
                                                                        is-anegative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway +
                                                                        is-anegative regulation of thrombin receptor signaling pathway
                                                                        is-atermination of G-protein coupled receptor signaling pathway
                                                                is-anegative regulation of gibberellic acid mediated signaling pathway
                                                                is-anegative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation
                                                                is-anegative regulation of glucocorticoid mediated signaling pathway
                                                                is-anegative regulation of glucose mediated signaling pathway
                                                                is-anegative regulation of glutamate receptor signaling pathway
                                                                is-anegative regulation of growth hormone receptor signaling pathway
                                                                is-anegative regulation of hepatocyte growth factor receptor signaling pathway
                                                                is-anegative regulation of hypoxia-inducible factor-1alpha signaling pathway
                                                                is-anegative regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
                                                                is-anegative regulation of insulin receptor signaling pathway +
                                                                is-anegative regulation of insulin-like growth factor receptor signaling pathway
                                                                is-anegative regulation of integrin-mediated signaling pathway
                                                                is-anegative regulation of intracellular signal transduction +
                                                                is-anegative regulation of intracellular steroid hormone receptor signaling pathway +
                                                                is-anegative regulation of lipopolysaccharide-mediated signaling pathway +
                                                                is-anegative regulation of nerve growth factor receptor activity
                                                                is-anegative regulation of netrin-activated signaling pathway
                                                                is-anegative regulation of neuronal signal transduction
                                                                is-anegative regulation of neurotrophin TRK receptor signaling pathway
                                                                is-anegative regulation of Notch signaling pathway +
                                                                is-anegative regulation of peptidoglycan recognition protein signaling pathway
                                                                is-anegative regulation of peroxisome proliferator activated receptor signaling pathway
                                                                is-anegative regulation of phosphorelay signal transduction system +
                                                                is-anegative regulation of platelet-derived growth factor receptor signaling pathway +
                                                                is-anegative regulation of red or far-red light signaling pathway
                                                                is-anegative regulation of retinoic acid receptor signaling pathway
                                                                is-anegative regulation of Roundabout signaling pathway +
                                                                is-anegative regulation of semaphorin-plexin signaling pathway
                                                                is-anegative regulation of sevenless signaling pathway
                                                                is-anegative regulation of signal transduction by receptor internalization +
                                                                is-anegative regulation of signal transduction in absence of ligand +
                                                                is-anegative regulation of signal transduction in response to host +
                                                                is-anegative regulation of signal transduction involved in conjugation with cellular fusion +
                                                                is-anegative regulation of smoothened signaling pathway +
                                                                is-anegative regulation of sphingolipid mediated signaling pathway
                                                                is-anegative regulation of SREBP signaling pathway +
                                                                is-anegative regulation of thyroid hormone mediated signaling pathway
                                                                is-anegative regulation of Toll signaling pathway
                                                                is-anegative regulation of toll-like receptor signaling pathway +
                                                                is-anegative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                                is-anegative regulation of vascular endothelial growth factor receptor signaling pathway
                                                                is-anegative regulation of vascular endothelial growth factor signaling pathway
                                                                is-anegative regulation of vitamin D receptor signaling pathway
                                                                is-anegative regulation of Wnt signaling pathway +
                                                                is-atermination of signal transduction +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-aregulation of cell communication
                                                is-anegative regulation of cell communication
                                                        is-anegative regulation of signal transduction
                                                                is-aextracellular negative regulation of signal transduction +
                                                                is-ametarhodopsin inactivation
                                                                is-anegative adaptation of signaling pathway +
                                                                is-anegative regulation by symbiont of host cAMP-mediated signal transduction +
                                                                is-anegative regulation by symbiont of host salicylic acid-mediated defense response +
                                                                is-anegative regulation of abscisic acid-activated signaling pathway
                                                                is-anegative regulation of anti-Mullerian hormone signaling pathway
                                                                is-anegative regulation of antigen receptor-mediated signaling pathway +
                                                                is-anegative regulation of apoptotic signaling pathway +
                                                                is-anegative regulation of auxin mediated signaling pathway
                                                                is-anegative regulation of brain-derived neurotrophic factor receptor signaling pathway +
                                                                is-anegative regulation of brassinosteroid mediated signaling pathway
                                                                is-anegative regulation of CD40 signaling pathway
                                                                is-anegative regulation of cytokine-mediated signaling pathway +
                                                                is-anegative regulation of cytokinin-activated signaling pathway
                                                                is-anegative regulation of endoplasmic reticulum unfolded protein response
                                                                is-anegative regulation of ephrin receptor signaling pathway
                                                                is-anegative regulation of ERBB signaling pathway +
                                                                is-anegative regulation of Fas signaling pathway
                                                                is-anegative regulation of fibroblast growth factor receptor signaling pathway +
                                                                is-anegative regulation of G-protein coupled receptor protein signaling pathway [GO:0045744] (61 genes, 82 annotations)
                                                                        is-adesensitization of G-protein coupled receptor protein signaling pathway +
                                                                        is-aG-protein coupled receptor catabolic process
                                                                        is-anegative regulation by host of symbiont G-protein coupled receptor protein signal transduction +
                                                                        is-anegative regulation by symbiont of host G-protein coupled receptor protein signal transduction +
                                                                        is-anegative regulation of adenosine receptor signaling pathway
                                                                        is-anegative regulation of adrenergic receptor signaling pathway +
                                                                        is-anegative regulation of dopamine receptor signaling pathway +
                                                                        is-anegative regulation of G-protein coupled receptor protein signaling pathway in response to host +
                                                                        is-anegative regulation of octopamine or tyramine signaling pathway +
                                                                        is-anegative regulation of opioid receptor signaling pathway +
                                                                        is-anegative regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion
                                                                        is-anegative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway +
                                                                        is-anegative regulation of thrombin receptor signaling pathway
                                                                        is-atermination of G-protein coupled receptor signaling pathway
                                                                is-anegative regulation of gibberellic acid mediated signaling pathway
                                                                is-anegative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation
                                                                is-anegative regulation of glucocorticoid mediated signaling pathway
                                                                is-anegative regulation of glucose mediated signaling pathway
                                                                is-anegative regulation of glutamate receptor signaling pathway
                                                                is-anegative regulation of growth hormone receptor signaling pathway
                                                                is-anegative regulation of hepatocyte growth factor receptor signaling pathway
                                                                is-anegative regulation of hypoxia-inducible factor-1alpha signaling pathway
                                                                is-anegative regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
                                                                is-anegative regulation of insulin receptor signaling pathway +
                                                                is-anegative regulation of insulin-like growth factor receptor signaling pathway
                                                                is-anegative regulation of integrin-mediated signaling pathway
                                                                is-anegative regulation of intracellular signal transduction +
                                                                is-anegative regulation of intracellular steroid hormone receptor signaling pathway +
                                                                is-anegative regulation of lipopolysaccharide-mediated signaling pathway +
                                                                is-anegative regulation of nerve growth factor receptor activity
                                                                is-anegative regulation of netrin-activated signaling pathway
                                                                is-anegative regulation of neuronal signal transduction
                                                                is-anegative regulation of neurotrophin TRK receptor signaling pathway
                                                                is-anegative regulation of Notch signaling pathway +
                                                                is-anegative regulation of peptidoglycan recognition protein signaling pathway
                                                                is-anegative regulation of peroxisome proliferator activated receptor signaling pathway
                                                                is-anegative regulation of phosphorelay signal transduction system +
                                                                is-anegative regulation of platelet-derived growth factor receptor signaling pathway +
                                                                is-anegative regulation of red or far-red light signaling pathway
                                                                is-anegative regulation of retinoic acid receptor signaling pathway
                                                                is-anegative regulation of Roundabout signaling pathway +
                                                                is-anegative regulation of semaphorin-plexin signaling pathway
                                                                is-anegative regulation of sevenless signaling pathway
                                                                is-anegative regulation of signal transduction by receptor internalization +
                                                                is-anegative regulation of signal transduction in absence of ligand +
                                                                is-anegative regulation of signal transduction in response to host +
                                                                is-anegative regulation of signal transduction involved in conjugation with cellular fusion +
                                                                is-anegative regulation of smoothened signaling pathway +
                                                                is-anegative regulation of sphingolipid mediated signaling pathway
                                                                is-anegative regulation of SREBP signaling pathway +
                                                                is-anegative regulation of thyroid hormone mediated signaling pathway
                                                                is-anegative regulation of Toll signaling pathway
                                                                is-anegative regulation of toll-like receptor signaling pathway +
                                                                is-anegative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                                is-anegative regulation of vascular endothelial growth factor receptor signaling pathway
                                                                is-anegative regulation of vascular endothelial growth factor signaling pathway
                                                                is-anegative regulation of vitamin D receptor signaling pathway
                                                                is-anegative regulation of Wnt signaling pathway +
                                                                is-atermination of signal transduction +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-aregulation of cell communication
                                                is-aregulation of signal transduction
                                                        is-anegative regulation of signal transduction
                                                                is-aextracellular negative regulation of signal transduction +
                                                                is-ametarhodopsin inactivation
                                                                is-anegative adaptation of signaling pathway +
                                                                is-anegative regulation by symbiont of host cAMP-mediated signal transduction +
                                                                is-anegative regulation by symbiont of host salicylic acid-mediated defense response +
                                                                is-anegative regulation of abscisic acid-activated signaling pathway
                                                                is-anegative regulation of anti-Mullerian hormone signaling pathway
                                                                is-anegative regulation of antigen receptor-mediated signaling pathway +
                                                                is-anegative regulation of apoptotic signaling pathway +
                                                                is-anegative regulation of auxin mediated signaling pathway
                                                                is-anegative regulation of brain-derived neurotrophic factor receptor signaling pathway +
                                                                is-anegative regulation of brassinosteroid mediated signaling pathway
                                                                is-anegative regulation of CD40 signaling pathway
                                                                is-anegative regulation of cytokine-mediated signaling pathway +
                                                                is-anegative regulation of cytokinin-activated signaling pathway
                                                                is-anegative regulation of endoplasmic reticulum unfolded protein response
                                                                is-anegative regulation of ephrin receptor signaling pathway
                                                                is-anegative regulation of ERBB signaling pathway +
                                                                is-anegative regulation of Fas signaling pathway
                                                                is-anegative regulation of fibroblast growth factor receptor signaling pathway +
                                                                is-anegative regulation of G-protein coupled receptor protein signaling pathway [GO:0045744] (61 genes, 82 annotations)
                                                                        is-adesensitization of G-protein coupled receptor protein signaling pathway +
                                                                        is-aG-protein coupled receptor catabolic process
                                                                        is-anegative regulation by host of symbiont G-protein coupled receptor protein signal transduction +
                                                                        is-anegative regulation by symbiont of host G-protein coupled receptor protein signal transduction +
                                                                        is-anegative regulation of adenosine receptor signaling pathway
                                                                        is-anegative regulation of adrenergic receptor signaling pathway +
                                                                        is-anegative regulation of dopamine receptor signaling pathway +
                                                                        is-anegative regulation of G-protein coupled receptor protein signaling pathway in response to host +
                                                                        is-anegative regulation of octopamine or tyramine signaling pathway +
                                                                        is-anegative regulation of opioid receptor signaling pathway +
                                                                        is-anegative regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion
                                                                        is-anegative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway +
                                                                        is-anegative regulation of thrombin receptor signaling pathway
                                                                        is-atermination of G-protein coupled receptor signaling pathway
                                                                is-anegative regulation of gibberellic acid mediated signaling pathway
                                                                is-anegative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation
                                                                is-anegative regulation of glucocorticoid mediated signaling pathway
                                                                is-anegative regulation of glucose mediated signaling pathway
                                                                is-anegative regulation of glutamate receptor signaling pathway
                                                                is-anegative regulation of growth hormone receptor signaling pathway
                                                                is-anegative regulation of hepatocyte growth factor receptor signaling pathway
                                                                is-anegative regulation of hypoxia-inducible factor-1alpha signaling pathway
                                                                is-anegative regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
                                                                is-anegative regulation of insulin receptor signaling pathway +
                                                                is-anegative regulation of insulin-like growth factor receptor signaling pathway
                                                                is-anegative regulation of integrin-mediated signaling pathway
                                                                is-anegative regulation of intracellular signal transduction +
                                                                is-anegative regulation of intracellular steroid hormone receptor signaling pathway +
                                                                is-anegative regulation of lipopolysaccharide-mediated signaling pathway +
                                                                is-anegative regulation of nerve growth factor receptor activity
                                                                is-anegative regulation of netrin-activated signaling pathway
                                                                is-anegative regulation of neuronal signal transduction
                                                                is-anegative regulation of neurotrophin TRK receptor signaling pathway
                                                                is-anegative regulation of Notch signaling pathway +
                                                                is-anegative regulation of peptidoglycan recognition protein signaling pathway
                                                                is-anegative regulation of peroxisome proliferator activated receptor signaling pathway
                                                                is-anegative regulation of phosphorelay signal transduction system +
                                                                is-anegative regulation of platelet-derived growth factor receptor signaling pathway +
                                                                is-anegative regulation of red or far-red light signaling pathway
                                                                is-anegative regulation of retinoic acid receptor signaling pathway
                                                                is-anegative regulation of Roundabout signaling pathway +
                                                                is-anegative regulation of semaphorin-plexin signaling pathway
                                                                is-anegative regulation of sevenless signaling pathway
                                                                is-anegative regulation of signal transduction by receptor internalization +
                                                                is-anegative regulation of signal transduction in absence of ligand +
                                                                is-anegative regulation of signal transduction in response to host +
                                                                is-anegative regulation of signal transduction involved in conjugation with cellular fusion +
                                                                is-anegative regulation of smoothened signaling pathway +
                                                                is-anegative regulation of sphingolipid mediated signaling pathway
                                                                is-anegative regulation of SREBP signaling pathway +
                                                                is-anegative regulation of thyroid hormone mediated signaling pathway
                                                                is-anegative regulation of Toll signaling pathway
                                                                is-anegative regulation of toll-like receptor signaling pathway +
                                                                is-anegative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                                is-anegative regulation of vascular endothelial growth factor receptor signaling pathway
                                                                is-anegative regulation of vascular endothelial growth factor signaling pathway
                                                                is-anegative regulation of vitamin D receptor signaling pathway
                                                                is-anegative regulation of Wnt signaling pathway +
                                                                is-atermination of signal transduction +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-aregulation of cell communication
                                                is-aregulation of signal transduction
                                                        is-aregulation of G-protein coupled receptor protein signaling pathway
                                                                is-across-receptor inhibition within G-protein coupled receptor heterodimer
                                                                is-amodulation by host of symbiont G-protein coupled receptor protein signal transduction +
                                                                is-amodulation by symbiont of host G-protein coupled receptor protein signal transduction +
                                                                is-anegative regulation of G-protein coupled receptor protein signaling pathway [GO:0045744] (61 genes, 82 annotations)
                                                                        is-adesensitization of G-protein coupled receptor protein signaling pathway +
                                                                        is-aG-protein coupled receptor catabolic process
                                                                        is-anegative regulation by host of symbiont G-protein coupled receptor protein signal transduction +
                                                                        is-anegative regulation by symbiont of host G-protein coupled receptor protein signal transduction +
                                                                        is-anegative regulation of adenosine receptor signaling pathway
                                                                        is-anegative regulation of adrenergic receptor signaling pathway +
                                                                        is-anegative regulation of dopamine receptor signaling pathway +
                                                                        is-anegative regulation of G-protein coupled receptor protein signaling pathway in response to host +
                                                                        is-anegative regulation of octopamine or tyramine signaling pathway +
                                                                        is-anegative regulation of opioid receptor signaling pathway +
                                                                        is-anegative regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion
                                                                        is-anegative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway +
                                                                        is-anegative regulation of thrombin receptor signaling pathway
                                                                        is-atermination of G-protein coupled receptor signaling pathway
                                                                is-apositive regulation of G-protein coupled receptor protein signaling pathway +
                                                                is-aprotein kinase C deactivation
                                                                is-aregulation of adenosine receptor signaling pathway +
                                                                is-aregulation of adrenergic receptor signaling pathway +
                                                                is-aregulation of dopamine receptor signaling pathway +
                                                                is-aregulation of endocannabinoid signaling pathway
                                                                is-aregulation of G-protein coupled receptor protein signaling pathway in response to host +
                                                                is-aregulation of octopamine or tyramine signaling pathway +
                                                                is-aregulation of opioid receptor signaling pathway +
                                                                is-aregulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion +
                                                                is-aregulation of phospholipase C-activating G-protein coupled receptor signaling pathway +
                                                                is-aregulation of proteinase activated receptor activity +
                                                                is-aregulation of rhodopsin mediated signaling pathway +
                                                                is-aregulation of thrombin receptor signaling pathway +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-asignal transduction
                                                is-acell surface receptor signaling pathway
                                                        is-aG-protein coupled receptor signaling pathway
                                                                is-aadrenergic receptor signaling pathway +
                                                                is-aangiotensin-activated signaling pathway +
                                                                is-aapelin receptor signaling pathway
                                                                is-abombesin receptor signaling pathway
                                                                is-acannabinoid signaling pathway +
                                                                is-acholecystokinin signaling pathway +
                                                                is-acomplement component C5a signaling pathway
                                                                is-adimeric G-protein coupled receptor signaling pathway +
                                                                is-adopamine receptor signaling pathway +
                                                                is-aendothelin receptor signaling pathway +
                                                                is-aepidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway
                                                                is-afollicle-stimulating hormone signaling pathway
                                                                is-aG-protein coupled acetylcholine receptor signaling pathway +
                                                                is-aG-protein coupled glutamate receptor signaling pathway +
                                                                is-aG-protein coupled purinergic receptor signaling pathway +
                                                                is-aG-protein coupled receptor signaling in absence of ligand
                                                                is-aG-protein coupled receptor signaling pathway involved in heart process +
                                                                is-aG-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger +
                                                                is-aG-protein coupled receptor signaling pathway, coupled to S1P second messenger
                                                                is-agamma-aminobutyric acid signaling pathway
                                                                is-agastric inhibitory peptide signaling pathway
                                                                part-ofheterotrimeric G-protein complex cycle
                                                                is-aluteinizing hormone signaling pathway +
                                                                negatively-regulatesnegative regulation of G-protein coupled receptor protein signaling pathway [GO:0045744] (61 genes, 82 annotations)
                                                                        is-adesensitization of G-protein coupled receptor protein signaling pathway +
                                                                        is-aG-protein coupled receptor catabolic process
                                                                        is-anegative regulation by host of symbiont G-protein coupled receptor protein signal transduction +
                                                                        is-anegative regulation by symbiont of host G-protein coupled receptor protein signal transduction +
                                                                        is-anegative regulation of adenosine receptor signaling pathway
                                                                        is-anegative regulation of adrenergic receptor signaling pathway +
                                                                        is-anegative regulation of dopamine receptor signaling pathway +
                                                                        is-anegative regulation of G-protein coupled receptor protein signaling pathway in response to host +
                                                                        is-anegative regulation of octopamine or tyramine signaling pathway +
                                                                        is-anegative regulation of opioid receptor signaling pathway +
                                                                        is-anegative regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion
                                                                        is-anegative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway +
                                                                        is-anegative regulation of thrombin receptor signaling pathway
                                                                        is-atermination of G-protein coupled receptor signaling pathway
                                                                is-aneuropeptide signaling pathway
                                                                is-aoctopamine or tyramine signaling pathway +
                                                                is-aopioid receptor signaling pathway +
                                                                is-apheromone-dependent signal transduction involved in conjugation with cellular fusion +
                                                                is-aphospholipase C-activating G-protein coupled receptor signaling pathway +
                                                                is-aphospholipase C-inhibiting G-protein coupled receptor signaling pathway
                                                                is-aphospholipase D-activating G-protein coupled receptor signaling pathway
                                                                positively-regulatespositive regulation of G-protein coupled receptor protein signaling pathway +
                                                                is-aprotein kinase C-activating G-protein coupled receptor signaling pathway
                                                                regulatesregulation of G-protein coupled receptor protein signaling pathway +
                                                                is-arhodopsin mediated signaling pathway +
                                                                is-aserotonin receptor signaling pathway +
                                                                is-asignal transduction involved in conjugation with mutual genetic exchange
                                                                is-asomatostatin receptor signaling pathway +
                                                                is-asphingosine-1-phosphate signaling pathway +
                                                                is-atachykinin receptor signaling pathway +
                                                                is-athrombin receptor signaling pathway +
                                                                is-athromboxane A2 signaling pathway
                                                                is-athyroid-stimulating hormone signaling pathway


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-asignal transduction
                                                is-acell surface receptor signaling pathway
                                                        is-aG-protein coupled receptor signaling pathway
                                                                regulatesregulation of G-protein coupled receptor protein signaling pathway
                                                                        is-across-receptor inhibition within G-protein coupled receptor heterodimer
                                                                        is-amodulation by host of symbiont G-protein coupled receptor protein signal transduction +
                                                                        is-amodulation by symbiont of host G-protein coupled receptor protein signal transduction +
                                                                        is-anegative regulation of G-protein coupled receptor protein signaling pathway [GO:0045744] (61 genes, 82 annotations)
                                                                                is-adesensitization of G-protein coupled receptor protein signaling pathway +
                                                                                is-aG-protein coupled receptor catabolic process
                                                                                is-anegative regulation by host of symbiont G-protein coupled receptor protein signal transduction +
                                                                                is-anegative regulation by symbiont of host G-protein coupled receptor protein signal transduction +
                                                                                is-anegative regulation of adenosine receptor signaling pathway
                                                                                is-anegative regulation of adrenergic receptor signaling pathway +
                                                                                is-anegative regulation of dopamine receptor signaling pathway +
                                                                                is-anegative regulation of G-protein coupled receptor protein signaling pathway in response to host +
                                                                                is-anegative regulation of octopamine or tyramine signaling pathway +
                                                                                is-anegative regulation of opioid receptor signaling pathway +
                                                                                is-anegative regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion
                                                                                is-anegative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway +
                                                                                is-anegative regulation of thrombin receptor signaling pathway
                                                                                is-atermination of G-protein coupled receptor signaling pathway
                                                                        is-apositive regulation of G-protein coupled receptor protein signaling pathway +
                                                                        is-aprotein kinase C deactivation
                                                                        is-aregulation of adenosine receptor signaling pathway +
                                                                        is-aregulation of adrenergic receptor signaling pathway +
                                                                        is-aregulation of dopamine receptor signaling pathway +
                                                                        is-aregulation of endocannabinoid signaling pathway
                                                                        is-aregulation of G-protein coupled receptor protein signaling pathway in response to host +
                                                                        is-aregulation of octopamine or tyramine signaling pathway +
                                                                        is-aregulation of opioid receptor signaling pathway +
                                                                        is-aregulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion +
                                                                        is-aregulation of phospholipase C-activating G-protein coupled receptor signaling pathway +
                                                                        is-aregulation of proteinase activated receptor activity +
                                                                        is-aregulation of rhodopsin mediated signaling pathway +
                                                                        is-aregulation of thrombin receptor signaling pathway +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-asignal transduction
                                                negatively-regulatesnegative regulation of signal transduction
                                                        is-aextracellular negative regulation of signal transduction +
                                                        is-ametarhodopsin inactivation
                                                        is-anegative adaptation of signaling pathway +
                                                        is-anegative regulation by symbiont of host cAMP-mediated signal transduction +
                                                        is-anegative regulation by symbiont of host salicylic acid-mediated defense response +
                                                        is-anegative regulation of abscisic acid-activated signaling pathway
                                                        is-anegative regulation of anti-Mullerian hormone signaling pathway
                                                        is-anegative regulation of antigen receptor-mediated signaling pathway +
                                                        is-anegative regulation of apoptotic signaling pathway +
                                                        is-anegative regulation of auxin mediated signaling pathway
                                                        is-anegative regulation of brain-derived neurotrophic factor receptor signaling pathway +
                                                        is-anegative regulation of brassinosteroid mediated signaling pathway
                                                        is-anegative regulation of CD40 signaling pathway
                                                        is-anegative regulation of cytokine-mediated signaling pathway +
                                                        is-anegative regulation of cytokinin-activated signaling pathway
                                                        is-anegative regulation of endoplasmic reticulum unfolded protein response
                                                        is-anegative regulation of ephrin receptor signaling pathway
                                                        is-anegative regulation of ERBB signaling pathway +
                                                        is-anegative regulation of Fas signaling pathway
                                                        is-anegative regulation of fibroblast growth factor receptor signaling pathway +
                                                        is-anegative regulation of G-protein coupled receptor protein signaling pathway [GO:0045744] (61 genes, 82 annotations)
                                                                is-adesensitization of G-protein coupled receptor protein signaling pathway +
                                                                is-aG-protein coupled receptor catabolic process
                                                                is-anegative regulation by host of symbiont G-protein coupled receptor protein signal transduction +
                                                                is-anegative regulation by symbiont of host G-protein coupled receptor protein signal transduction +
                                                                is-anegative regulation of adenosine receptor signaling pathway
                                                                is-anegative regulation of adrenergic receptor signaling pathway +
                                                                is-anegative regulation of dopamine receptor signaling pathway +
                                                                is-anegative regulation of G-protein coupled receptor protein signaling pathway in response to host +
                                                                is-anegative regulation of octopamine or tyramine signaling pathway +
                                                                is-anegative regulation of opioid receptor signaling pathway +
                                                                is-anegative regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion
                                                                is-anegative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway +
                                                                is-anegative regulation of thrombin receptor signaling pathway
                                                                is-atermination of G-protein coupled receptor signaling pathway
                                                        is-anegative regulation of gibberellic acid mediated signaling pathway
                                                        is-anegative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation
                                                        is-anegative regulation of glucocorticoid mediated signaling pathway
                                                        is-anegative regulation of glucose mediated signaling pathway
                                                        is-anegative regulation of glutamate receptor signaling pathway
                                                        is-anegative regulation of growth hormone receptor signaling pathway
                                                        is-anegative regulation of hepatocyte growth factor receptor signaling pathway
                                                        is-anegative regulation of hypoxia-inducible factor-1alpha signaling pathway
                                                        is-anegative regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
                                                        is-anegative regulation of insulin receptor signaling pathway +
                                                        is-anegative regulation of insulin-like growth factor receptor signaling pathway
                                                        is-anegative regulation of integrin-mediated signaling pathway
                                                        is-anegative regulation of intracellular signal transduction +
                                                        is-anegative regulation of intracellular steroid hormone receptor signaling pathway +
                                                        is-anegative regulation of lipopolysaccharide-mediated signaling pathway +
                                                        is-anegative regulation of nerve growth factor receptor activity
                                                        is-anegative regulation of netrin-activated signaling pathway
                                                        is-anegative regulation of neuronal signal transduction
                                                        is-anegative regulation of neurotrophin TRK receptor signaling pathway
                                                        is-anegative regulation of Notch signaling pathway +
                                                        is-anegative regulation of peptidoglycan recognition protein signaling pathway
                                                        is-anegative regulation of peroxisome proliferator activated receptor signaling pathway
                                                        is-anegative regulation of phosphorelay signal transduction system +
                                                        is-anegative regulation of platelet-derived growth factor receptor signaling pathway +
                                                        is-anegative regulation of red or far-red light signaling pathway
                                                        is-anegative regulation of retinoic acid receptor signaling pathway
                                                        is-anegative regulation of Roundabout signaling pathway +
                                                        is-anegative regulation of semaphorin-plexin signaling pathway
                                                        is-anegative regulation of sevenless signaling pathway
                                                        is-anegative regulation of signal transduction by receptor internalization +
                                                        is-anegative regulation of signal transduction in absence of ligand +
                                                        is-anegative regulation of signal transduction in response to host +
                                                        is-anegative regulation of signal transduction involved in conjugation with cellular fusion +
                                                        is-anegative regulation of smoothened signaling pathway +
                                                        is-anegative regulation of sphingolipid mediated signaling pathway
                                                        is-anegative regulation of SREBP signaling pathway +
                                                        is-anegative regulation of thyroid hormone mediated signaling pathway
                                                        is-anegative regulation of Toll signaling pathway
                                                        is-anegative regulation of toll-like receptor signaling pathway +
                                                        is-anegative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                        is-anegative regulation of vascular endothelial growth factor receptor signaling pathway
                                                        is-anegative regulation of vascular endothelial growth factor signaling pathway
                                                        is-anegative regulation of vitamin D receptor signaling pathway
                                                        is-anegative regulation of Wnt signaling pathway +
                                                        is-atermination of signal transduction +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-asignal transduction
                                                regulatesregulation of signal transduction
                                                        is-anegative regulation of signal transduction
                                                                is-aextracellular negative regulation of signal transduction +
                                                                is-ametarhodopsin inactivation
                                                                is-anegative adaptation of signaling pathway +
                                                                is-anegative regulation by symbiont of host cAMP-mediated signal transduction +
                                                                is-anegative regulation by symbiont of host salicylic acid-mediated defense response +
                                                                is-anegative regulation of abscisic acid-activated signaling pathway
                                                                is-anegative regulation of anti-Mullerian hormone signaling pathway
                                                                is-anegative regulation of antigen receptor-mediated signaling pathway +
                                                                is-anegative regulation of apoptotic signaling pathway +
                                                                is-anegative regulation of auxin mediated signaling pathway
                                                                is-anegative regulation of brain-derived neurotrophic factor receptor signaling pathway +
                                                                is-anegative regulation of brassinosteroid mediated signaling pathway
                                                                is-anegative regulation of CD40 signaling pathway
                                                                is-anegative regulation of cytokine-mediated signaling pathway +
                                                                is-anegative regulation of cytokinin-activated signaling pathway
                                                                is-anegative regulation of endoplasmic reticulum unfolded protein response
                                                                is-anegative regulation of ephrin receptor signaling pathway
                                                                is-anegative regulation of ERBB signaling pathway +
                                                                is-anegative regulation of Fas signaling pathway
                                                                is-anegative regulation of fibroblast growth factor receptor signaling pathway +
                                                                is-anegative regulation of G-protein coupled receptor protein signaling pathway [GO:0045744] (61 genes, 82 annotations)
                                                                        is-adesensitization of G-protein coupled receptor protein signaling pathway +
                                                                        is-aG-protein coupled receptor catabolic process
                                                                        is-anegative regulation by host of symbiont G-protein coupled receptor protein signal transduction +
                                                                        is-anegative regulation by symbiont of host G-protein coupled receptor protein signal transduction +
                                                                        is-anegative regulation of adenosine receptor signaling pathway
                                                                        is-anegative regulation of adrenergic receptor signaling pathway +
                                                                        is-anegative regulation of dopamine receptor signaling pathway +
                                                                        is-anegative regulation of G-protein coupled receptor protein signaling pathway in response to host +
                                                                        is-anegative regulation of octopamine or tyramine signaling pathway +
                                                                        is-anegative regulation of opioid receptor signaling pathway +
                                                                        is-anegative regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion
                                                                        is-anegative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway +
                                                                        is-anegative regulation of thrombin receptor signaling pathway
                                                                        is-atermination of G-protein coupled receptor signaling pathway
                                                                is-anegative regulation of gibberellic acid mediated signaling pathway
                                                                is-anegative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation
                                                                is-anegative regulation of glucocorticoid mediated signaling pathway
                                                                is-anegative regulation of glucose mediated signaling pathway
                                                                is-anegative regulation of glutamate receptor signaling pathway
                                                                is-anegative regulation of growth hormone receptor signaling pathway
                                                                is-anegative regulation of hepatocyte growth factor receptor signaling pathway
                                                                is-anegative regulation of hypoxia-inducible factor-1alpha signaling pathway
                                                                is-anegative regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
                                                                is-anegative regulation of insulin receptor signaling pathway +
                                                                is-anegative regulation of insulin-like growth factor receptor signaling pathway
                                                                is-anegative regulation of integrin-mediated signaling pathway
                                                                is-anegative regulation of intracellular signal transduction +
                                                                is-anegative regulation of intracellular steroid hormone receptor signaling pathway +
                                                                is-anegative regulation of lipopolysaccharide-mediated signaling pathway +
                                                                is-anegative regulation of nerve growth factor receptor activity
                                                                is-anegative regulation of netrin-activated signaling pathway
                                                                is-anegative regulation of neuronal signal transduction
                                                                is-anegative regulation of neurotrophin TRK receptor signaling pathway
                                                                is-anegative regulation of Notch signaling pathway +
                                                                is-anegative regulation of peptidoglycan recognition protein signaling pathway
                                                                is-anegative regulation of peroxisome proliferator activated receptor signaling pathway
                                                                is-anegative regulation of phosphorelay signal transduction system +
                                                                is-anegative regulation of platelet-derived growth factor receptor signaling pathway +
                                                                is-anegative regulation of red or far-red light signaling pathway
                                                                is-anegative regulation of retinoic acid receptor signaling pathway
                                                                is-anegative regulation of Roundabout signaling pathway +
                                                                is-anegative regulation of semaphorin-plexin signaling pathway
                                                                is-anegative regulation of sevenless signaling pathway
                                                                is-anegative regulation of signal transduction by receptor internalization +
                                                                is-anegative regulation of signal transduction in absence of ligand +
                                                                is-anegative regulation of signal transduction in response to host +
                                                                is-anegative regulation of signal transduction involved in conjugation with cellular fusion +
                                                                is-anegative regulation of smoothened signaling pathway +
                                                                is-anegative regulation of sphingolipid mediated signaling pathway
                                                                is-anegative regulation of SREBP signaling pathway +
                                                                is-anegative regulation of thyroid hormone mediated signaling pathway
                                                                is-anegative regulation of Toll signaling pathway
                                                                is-anegative regulation of toll-like receptor signaling pathway +
                                                                is-anegative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                                is-anegative regulation of vascular endothelial growth factor receptor signaling pathway
                                                                is-anegative regulation of vascular endothelial growth factor signaling pathway
                                                                is-anegative regulation of vitamin D receptor signaling pathway
                                                                is-anegative regulation of Wnt signaling pathway +
                                                                is-atermination of signal transduction +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-asignal transduction
                                                regulatesregulation of signal transduction
                                                        is-aregulation of G-protein coupled receptor protein signaling pathway
                                                                is-across-receptor inhibition within G-protein coupled receptor heterodimer
                                                                is-amodulation by host of symbiont G-protein coupled receptor protein signal transduction +
                                                                is-amodulation by symbiont of host G-protein coupled receptor protein signal transduction +
                                                                is-anegative regulation of G-protein coupled receptor protein signaling pathway [GO:0045744] (61 genes, 82 annotations)
                                                                        is-adesensitization of G-protein coupled receptor protein signaling pathway +
                                                                        is-aG-protein coupled receptor catabolic process
                                                                        is-anegative regulation by host of symbiont G-protein coupled receptor protein signal transduction +
                                                                        is-anegative regulation by symbiont of host G-protein coupled receptor protein signal transduction +
                                                                        is-anegative regulation of adenosine receptor signaling pathway
                                                                        is-anegative regulation of adrenergic receptor signaling pathway +
                                                                        is-anegative regulation of dopamine receptor signaling pathway +
                                                                        is-anegative regulation of G-protein coupled receptor protein signaling pathway in response to host +
                                                                        is-anegative regulation of octopamine or tyramine signaling pathway +
                                                                        is-anegative regulation of opioid receptor signaling pathway +
                                                                        is-anegative regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion
                                                                        is-anegative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway +
                                                                        is-anegative regulation of thrombin receptor signaling pathway
                                                                        is-atermination of G-protein coupled receptor signaling pathway
                                                                is-apositive regulation of G-protein coupled receptor protein signaling pathway +
                                                                is-aprotein kinase C deactivation
                                                                is-aregulation of adenosine receptor signaling pathway +
                                                                is-aregulation of adrenergic receptor signaling pathway +
                                                                is-aregulation of dopamine receptor signaling pathway +
                                                                is-aregulation of endocannabinoid signaling pathway
                                                                is-aregulation of G-protein coupled receptor protein signaling pathway in response to host +
                                                                is-aregulation of octopamine or tyramine signaling pathway +
                                                                is-aregulation of opioid receptor signaling pathway +
                                                                is-aregulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion +
                                                                is-aregulation of phospholipase C-activating G-protein coupled receptor signaling pathway +
                                                                is-aregulation of proteinase activated receptor activity +
                                                                is-aregulation of rhodopsin mediated signaling pathway +
                                                                is-aregulation of thrombin receptor signaling pathway +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of response to stimulus
                                        is-anegative regulation of response to stimulus
                                                is-anegative regulation of signal transduction
                                                        is-aextracellular negative regulation of signal transduction +
                                                        is-ametarhodopsin inactivation
                                                        is-anegative adaptation of signaling pathway +
                                                        is-anegative regulation by symbiont of host cAMP-mediated signal transduction +
                                                        is-anegative regulation by symbiont of host salicylic acid-mediated defense response +
                                                        is-anegative regulation of abscisic acid-activated signaling pathway
                                                        is-anegative regulation of anti-Mullerian hormone signaling pathway
                                                        is-anegative regulation of antigen receptor-mediated signaling pathway +
                                                        is-anegative regulation of apoptotic signaling pathway +
                                                        is-anegative regulation of auxin mediated signaling pathway
                                                        is-anegative regulation of brain-derived neurotrophic factor receptor signaling pathway +
                                                        is-anegative regulation of brassinosteroid mediated signaling pathway
                                                        is-anegative regulation of CD40 signaling pathway
                                                        is-anegative regulation of cytokine-mediated signaling pathway +
                                                        is-anegative regulation of cytokinin-activated signaling pathway
                                                        is-anegative regulation of endoplasmic reticulum unfolded protein response
                                                        is-anegative regulation of ephrin receptor signaling pathway
                                                        is-anegative regulation of ERBB signaling pathway +
                                                        is-anegative regulation of Fas signaling pathway
                                                        is-anegative regulation of fibroblast growth factor receptor signaling pathway +
                                                        is-anegative regulation of G-protein coupled receptor protein signaling pathway [GO:0045744] (61 genes, 82 annotations)
                                                                is-adesensitization of G-protein coupled receptor protein signaling pathway +
                                                                is-aG-protein coupled receptor catabolic process
                                                                is-anegative regulation by host of symbiont G-protein coupled receptor protein signal transduction +
                                                                is-anegative regulation by symbiont of host G-protein coupled receptor protein signal transduction +
                                                                is-anegative regulation of adenosine receptor signaling pathway
                                                                is-anegative regulation of adrenergic receptor signaling pathway +
                                                                is-anegative regulation of dopamine receptor signaling pathway +
                                                                is-anegative regulation of G-protein coupled receptor protein signaling pathway in response to host +
                                                                is-anegative regulation of octopamine or tyramine signaling pathway +
                                                                is-anegative regulation of opioid receptor signaling pathway +
                                                                is-anegative regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion
                                                                is-anegative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway +
                                                                is-anegative regulation of thrombin receptor signaling pathway
                                                                is-atermination of G-protein coupled receptor signaling pathway
                                                        is-anegative regulation of gibberellic acid mediated signaling pathway
                                                        is-anegative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation
                                                        is-anegative regulation of glucocorticoid mediated signaling pathway
                                                        is-anegative regulation of glucose mediated signaling pathway
                                                        is-anegative regulation of glutamate receptor signaling pathway
                                                        is-anegative regulation of growth hormone receptor signaling pathway
                                                        is-anegative regulation of hepatocyte growth factor receptor signaling pathway
                                                        is-anegative regulation of hypoxia-inducible factor-1alpha signaling pathway
                                                        is-anegative regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
                                                        is-anegative regulation of insulin receptor signaling pathway +
                                                        is-anegative regulation of insulin-like growth factor receptor signaling pathway
                                                        is-anegative regulation of integrin-mediated signaling pathway
                                                        is-anegative regulation of intracellular signal transduction +
                                                        is-anegative regulation of intracellular steroid hormone receptor signaling pathway +
                                                        is-anegative regulation of lipopolysaccharide-mediated signaling pathway +
                                                        is-anegative regulation of nerve growth factor receptor activity
                                                        is-anegative regulation of netrin-activated signaling pathway
                                                        is-anegative regulation of neuronal signal transduction
                                                        is-anegative regulation of neurotrophin TRK receptor signaling pathway
                                                        is-anegative regulation of Notch signaling pathway +
                                                        is-anegative regulation of peptidoglycan recognition protein signaling pathway
                                                        is-anegative regulation of peroxisome proliferator activated receptor signaling pathway
                                                        is-anegative regulation of phosphorelay signal transduction system +
                                                        is-anegative regulation of platelet-derived growth factor receptor signaling pathway +
                                                        is-anegative regulation of red or far-red light signaling pathway
                                                        is-anegative regulation of retinoic acid receptor signaling pathway
                                                        is-anegative regulation of Roundabout signaling pathway +
                                                        is-anegative regulation of semaphorin-plexin signaling pathway
                                                        is-anegative regulation of sevenless signaling pathway
                                                        is-anegative regulation of signal transduction by receptor internalization +
                                                        is-anegative regulation of signal transduction in absence of ligand +
                                                        is-anegative regulation of signal transduction in response to host +
                                                        is-anegative regulation of signal transduction involved in conjugation with cellular fusion +
                                                        is-anegative regulation of smoothened signaling pathway +
                                                        is-anegative regulation of sphingolipid mediated signaling pathway
                                                        is-anegative regulation of SREBP signaling pathway +
                                                        is-anegative regulation of thyroid hormone mediated signaling pathway
                                                        is-anegative regulation of Toll signaling pathway
                                                        is-anegative regulation of toll-like receptor signaling pathway +
                                                        is-anegative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                        is-anegative regulation of vascular endothelial growth factor receptor signaling pathway
                                                        is-anegative regulation of vascular endothelial growth factor signaling pathway
                                                        is-anegative regulation of vitamin D receptor signaling pathway
                                                        is-anegative regulation of Wnt signaling pathway +
                                                        is-atermination of signal transduction +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of response to stimulus
                                        is-aregulation of signal transduction
                                                is-anegative regulation of signal transduction
                                                        is-aextracellular negative regulation of signal transduction +
                                                        is-ametarhodopsin inactivation
                                                        is-anegative adaptation of signaling pathway +
                                                        is-anegative regulation by symbiont of host cAMP-mediated signal transduction +
                                                        is-anegative regulation by symbiont of host salicylic acid-mediated defense response +
                                                        is-anegative regulation of abscisic acid-activated signaling pathway
                                                        is-anegative regulation of anti-Mullerian hormone signaling pathway
                                                        is-anegative regulation of antigen receptor-mediated signaling pathway +
                                                        is-anegative regulation of apoptotic signaling pathway +
                                                        is-anegative regulation of auxin mediated signaling pathway
                                                        is-anegative regulation of brain-derived neurotrophic factor receptor signaling pathway +
                                                        is-anegative regulation of brassinosteroid mediated signaling pathway
                                                        is-anegative regulation of CD40 signaling pathway
                                                        is-anegative regulation of cytokine-mediated signaling pathway +
                                                        is-anegative regulation of cytokinin-activated signaling pathway
                                                        is-anegative regulation of endoplasmic reticulum unfolded protein response
                                                        is-anegative regulation of ephrin receptor signaling pathway
                                                        is-anegative regulation of ERBB signaling pathway +
                                                        is-anegative regulation of Fas signaling pathway
                                                        is-anegative regulation of fibroblast growth factor receptor signaling pathway +
                                                        is-anegative regulation of G-protein coupled receptor protein signaling pathway [GO:0045744] (61 genes, 82 annotations)
                                                                is-adesensitization of G-protein coupled receptor protein signaling pathway +
                                                                is-aG-protein coupled receptor catabolic process
                                                                is-anegative regulation by host of symbiont G-protein coupled receptor protein signal transduction +
                                                                is-anegative regulation by symbiont of host G-protein coupled receptor protein signal transduction +
                                                                is-anegative regulation of adenosine receptor signaling pathway
                                                                is-anegative regulation of adrenergic receptor signaling pathway +
                                                                is-anegative regulation of dopamine receptor signaling pathway +
                                                                is-anegative regulation of G-protein coupled receptor protein signaling pathway in response to host +
                                                                is-anegative regulation of octopamine or tyramine signaling pathway +
                                                                is-anegative regulation of opioid receptor signaling pathway +
                                                                is-anegative regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion
                                                                is-anegative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway +
                                                                is-anegative regulation of thrombin receptor signaling pathway
                                                                is-atermination of G-protein coupled receptor signaling pathway
                                                        is-anegative regulation of gibberellic acid mediated signaling pathway
                                                        is-anegative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation
                                                        is-anegative regulation of glucocorticoid mediated signaling pathway
                                                        is-anegative regulation of glucose mediated signaling pathway
                                                        is-anegative regulation of glutamate receptor signaling pathway
                                                        is-anegative regulation of growth hormone receptor signaling pathway
                                                        is-anegative regulation of hepatocyte growth factor receptor signaling pathway
                                                        is-anegative regulation of hypoxia-inducible factor-1alpha signaling pathway
                                                        is-anegative regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
                                                        is-anegative regulation of insulin receptor signaling pathway +
                                                        is-anegative regulation of insulin-like growth factor receptor signaling pathway
                                                        is-anegative regulation of integrin-mediated signaling pathway
                                                        is-anegative regulation of intracellular signal transduction +
                                                        is-anegative regulation of intracellular steroid hormone receptor signaling pathway +
                                                        is-anegative regulation of lipopolysaccharide-mediated signaling pathway +
                                                        is-anegative regulation of nerve growth factor receptor activity
                                                        is-anegative regulation of netrin-activated signaling pathway
                                                        is-anegative regulation of neuronal signal transduction
                                                        is-anegative regulation of neurotrophin TRK receptor signaling pathway
                                                        is-anegative regulation of Notch signaling pathway +
                                                        is-anegative regulation of peptidoglycan recognition protein signaling pathway
                                                        is-anegative regulation of peroxisome proliferator activated receptor signaling pathway
                                                        is-anegative regulation of phosphorelay signal transduction system +
                                                        is-anegative regulation of platelet-derived growth factor receptor signaling pathway +
                                                        is-anegative regulation of red or far-red light signaling pathway
                                                        is-anegative regulation of retinoic acid receptor signaling pathway
                                                        is-anegative regulation of Roundabout signaling pathway +
                                                        is-anegative regulation of semaphorin-plexin signaling pathway
                                                        is-anegative regulation of sevenless signaling pathway
                                                        is-anegative regulation of signal transduction by receptor internalization +
                                                        is-anegative regulation of signal transduction in absence of ligand +
                                                        is-anegative regulation of signal transduction in response to host +
                                                        is-anegative regulation of signal transduction involved in conjugation with cellular fusion +
                                                        is-anegative regulation of smoothened signaling pathway +
                                                        is-anegative regulation of sphingolipid mediated signaling pathway
                                                        is-anegative regulation of SREBP signaling pathway +
                                                        is-anegative regulation of thyroid hormone mediated signaling pathway
                                                        is-anegative regulation of Toll signaling pathway
                                                        is-anegative regulation of toll-like receptor signaling pathway +
                                                        is-anegative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                        is-anegative regulation of vascular endothelial growth factor receptor signaling pathway
                                                        is-anegative regulation of vascular endothelial growth factor signaling pathway
                                                        is-anegative regulation of vitamin D receptor signaling pathway
                                                        is-anegative regulation of Wnt signaling pathway +
                                                        is-atermination of signal transduction +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of response to stimulus
                                        is-aregulation of signal transduction
                                                is-aregulation of G-protein coupled receptor protein signaling pathway
                                                        is-across-receptor inhibition within G-protein coupled receptor heterodimer
                                                        is-amodulation by host of symbiont G-protein coupled receptor protein signal transduction +
                                                        is-amodulation by symbiont of host G-protein coupled receptor protein signal transduction +
                                                        is-anegative regulation of G-protein coupled receptor protein signaling pathway [GO:0045744] (61 genes, 82 annotations)
                                                                is-adesensitization of G-protein coupled receptor protein signaling pathway +
                                                                is-aG-protein coupled receptor catabolic process
                                                                is-anegative regulation by host of symbiont G-protein coupled receptor protein signal transduction +
                                                                is-anegative regulation by symbiont of host G-protein coupled receptor protein signal transduction +
                                                                is-anegative regulation of adenosine receptor signaling pathway
                                                                is-anegative regulation of adrenergic receptor signaling pathway +
                                                                is-anegative regulation of dopamine receptor signaling pathway +
                                                                is-anegative regulation of G-protein coupled receptor protein signaling pathway in response to host +
                                                                is-anegative regulation of octopamine or tyramine signaling pathway +
                                                                is-anegative regulation of opioid receptor signaling pathway +
                                                                is-anegative regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion
                                                                is-anegative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway +
                                                                is-anegative regulation of thrombin receptor signaling pathway
                                                                is-atermination of G-protein coupled receptor signaling pathway
                                                        is-apositive regulation of G-protein coupled receptor protein signaling pathway +
                                                        is-aprotein kinase C deactivation
                                                        is-aregulation of adenosine receptor signaling pathway +
                                                        is-aregulation of adrenergic receptor signaling pathway +
                                                        is-aregulation of dopamine receptor signaling pathway +
                                                        is-aregulation of endocannabinoid signaling pathway
                                                        is-aregulation of G-protein coupled receptor protein signaling pathway in response to host +
                                                        is-aregulation of octopamine or tyramine signaling pathway +
                                                        is-aregulation of opioid receptor signaling pathway +
                                                        is-aregulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion +
                                                        is-aregulation of phospholipase C-activating G-protein coupled receptor signaling pathway +
                                                        is-aregulation of proteinase activated receptor activity +
                                                        is-aregulation of rhodopsin mediated signaling pathway +
                                                        is-aregulation of thrombin receptor signaling pathway +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of signaling
                                        is-anegative regulation of signaling
                                                is-anegative regulation of signal transduction
                                                        is-aextracellular negative regulation of signal transduction +
                                                        is-ametarhodopsin inactivation
                                                        is-anegative adaptation of signaling pathway +
                                                        is-anegative regulation by symbiont of host cAMP-mediated signal transduction +
                                                        is-anegative regulation by symbiont of host salicylic acid-mediated defense response +
                                                        is-anegative regulation of abscisic acid-activated signaling pathway
                                                        is-anegative regulation of anti-Mullerian hormone signaling pathway
                                                        is-anegative regulation of antigen receptor-mediated signaling pathway +
                                                        is-anegative regulation of apoptotic signaling pathway +
                                                        is-anegative regulation of auxin mediated signaling pathway
                                                        is-anegative regulation of brain-derived neurotrophic factor receptor signaling pathway +
                                                        is-anegative regulation of brassinosteroid mediated signaling pathway
                                                        is-anegative regulation of CD40 signaling pathway
                                                        is-anegative regulation of cytokine-mediated signaling pathway +
                                                        is-anegative regulation of cytokinin-activated signaling pathway
                                                        is-anegative regulation of endoplasmic reticulum unfolded protein response
                                                        is-anegative regulation of ephrin receptor signaling pathway
                                                        is-anegative regulation of ERBB signaling pathway +
                                                        is-anegative regulation of Fas signaling pathway
                                                        is-anegative regulation of fibroblast growth factor receptor signaling pathway +
                                                        is-anegative regulation of G-protein coupled receptor protein signaling pathway [GO:0045744] (61 genes, 82 annotations)
                                                                is-adesensitization of G-protein coupled receptor protein signaling pathway +
                                                                is-aG-protein coupled receptor catabolic process
                                                                is-anegative regulation by host of symbiont G-protein coupled receptor protein signal transduction +
                                                                is-anegative regulation by symbiont of host G-protein coupled receptor protein signal transduction +
                                                                is-anegative regulation of adenosine receptor signaling pathway
                                                                is-anegative regulation of adrenergic receptor signaling pathway +
                                                                is-anegative regulation of dopamine receptor signaling pathway +
                                                                is-anegative regulation of G-protein coupled receptor protein signaling pathway in response to host +
                                                                is-anegative regulation of octopamine or tyramine signaling pathway +
                                                                is-anegative regulation of opioid receptor signaling pathway +
                                                                is-anegative regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion
                                                                is-anegative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway +
                                                                is-anegative regulation of thrombin receptor signaling pathway
                                                                is-atermination of G-protein coupled receptor signaling pathway
                                                        is-anegative regulation of gibberellic acid mediated signaling pathway
                                                        is-anegative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation
                                                        is-anegative regulation of glucocorticoid mediated signaling pathway
                                                        is-anegative regulation of glucose mediated signaling pathway
                                                        is-anegative regulation of glutamate receptor signaling pathway
                                                        is-anegative regulation of growth hormone receptor signaling pathway
                                                        is-anegative regulation of hepatocyte growth factor receptor signaling pathway
                                                        is-anegative regulation of hypoxia-inducible factor-1alpha signaling pathway
                                                        is-anegative regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
                                                        is-anegative regulation of insulin receptor signaling pathway +
                                                        is-anegative regulation of insulin-like growth factor receptor signaling pathway
                                                        is-anegative regulation of integrin-mediated signaling pathway
                                                        is-anegative regulation of intracellular signal transduction +
                                                        is-anegative regulation of intracellular steroid hormone receptor signaling pathway +
                                                        is-anegative regulation of lipopolysaccharide-mediated signaling pathway +
                                                        is-anegative regulation of nerve growth factor receptor activity
                                                        is-anegative regulation of netrin-activated signaling pathway
                                                        is-anegative regulation of neuronal signal transduction
                                                        is-anegative regulation of neurotrophin TRK receptor signaling pathway
                                                        is-anegative regulation of Notch signaling pathway +
                                                        is-anegative regulation of peptidoglycan recognition protein signaling pathway
                                                        is-anegative regulation of peroxisome proliferator activated receptor signaling pathway
                                                        is-anegative regulation of phosphorelay signal transduction system +
                                                        is-anegative regulation of platelet-derived growth factor receptor signaling pathway +
                                                        is-anegative regulation of red or far-red light signaling pathway
                                                        is-anegative regulation of retinoic acid receptor signaling pathway
                                                        is-anegative regulation of Roundabout signaling pathway +
                                                        is-anegative regulation of semaphorin-plexin signaling pathway
                                                        is-anegative regulation of sevenless signaling pathway
                                                        is-anegative regulation of signal transduction by receptor internalization +
                                                        is-anegative regulation of signal transduction in absence of ligand +
                                                        is-anegative regulation of signal transduction in response to host +
                                                        is-anegative regulation of signal transduction involved in conjugation with cellular fusion +
                                                        is-anegative regulation of smoothened signaling pathway +
                                                        is-anegative regulation of sphingolipid mediated signaling pathway
                                                        is-anegative regulation of SREBP signaling pathway +
                                                        is-anegative regulation of thyroid hormone mediated signaling pathway
                                                        is-anegative regulation of Toll signaling pathway
                                                        is-anegative regulation of toll-like receptor signaling pathway +
                                                        is-anegative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                        is-anegative regulation of vascular endothelial growth factor receptor signaling pathway
                                                        is-anegative regulation of vascular endothelial growth factor signaling pathway
                                                        is-anegative regulation of vitamin D receptor signaling pathway
                                                        is-anegative regulation of Wnt signaling pathway +
                                                        is-atermination of signal transduction +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of signaling
                                        is-aregulation of signal transduction
                                                is-anegative regulation of signal transduction
                                                        is-aextracellular negative regulation of signal transduction +
                                                        is-ametarhodopsin inactivation
                                                        is-anegative adaptation of signaling pathway +
                                                        is-anegative regulation by symbiont of host cAMP-mediated signal transduction +
                                                        is-anegative regulation by symbiont of host salicylic acid-mediated defense response +
                                                        is-anegative regulation of abscisic acid-activated signaling pathway
                                                        is-anegative regulation of anti-Mullerian hormone signaling pathway
                                                        is-anegative regulation of antigen receptor-mediated signaling pathway +
                                                        is-anegative regulation of apoptotic signaling pathway +
                                                        is-anegative regulation of auxin mediated signaling pathway
                                                        is-anegative regulation of brain-derived neurotrophic factor receptor signaling pathway +
                                                        is-anegative regulation of brassinosteroid mediated signaling pathway
                                                        is-anegative regulation of CD40 signaling pathway
                                                        is-anegative regulation of cytokine-mediated signaling pathway +
                                                        is-anegative regulation of cytokinin-activated signaling pathway
                                                        is-anegative regulation of endoplasmic reticulum unfolded protein response
                                                        is-anegative regulation of ephrin receptor signaling pathway
                                                        is-anegative regulation of ERBB signaling pathway +
                                                        is-anegative regulation of Fas signaling pathway
                                                        is-anegative regulation of fibroblast growth factor receptor signaling pathway +
                                                        is-anegative regulation of G-protein coupled receptor protein signaling pathway [GO:0045744] (61 genes, 82 annotations)
                                                                is-adesensitization of G-protein coupled receptor protein signaling pathway +
                                                                is-aG-protein coupled receptor catabolic process
                                                                is-anegative regulation by host of symbiont G-protein coupled receptor protein signal transduction +
                                                                is-anegative regulation by symbiont of host G-protein coupled receptor protein signal transduction +
                                                                is-anegative regulation of adenosine receptor signaling pathway
                                                                is-anegative regulation of adrenergic receptor signaling pathway +
                                                                is-anegative regulation of dopamine receptor signaling pathway +
                                                                is-anegative regulation of G-protein coupled receptor protein signaling pathway in response to host +
                                                                is-anegative regulation of octopamine or tyramine signaling pathway +
                                                                is-anegative regulation of opioid receptor signaling pathway +
                                                                is-anegative regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion
                                                                is-anegative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway +
                                                                is-anegative regulation of thrombin receptor signaling pathway
                                                                is-atermination of G-protein coupled receptor signaling pathway
                                                        is-anegative regulation of gibberellic acid mediated signaling pathway
                                                        is-anegative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation
                                                        is-anegative regulation of glucocorticoid mediated signaling pathway
                                                        is-anegative regulation of glucose mediated signaling pathway
                                                        is-anegative regulation of glutamate receptor signaling pathway
                                                        is-anegative regulation of growth hormone receptor signaling pathway
                                                        is-anegative regulation of hepatocyte growth factor receptor signaling pathway
                                                        is-anegative regulation of hypoxia-inducible factor-1alpha signaling pathway
                                                        is-anegative regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
                                                        is-anegative regulation of insulin receptor signaling pathway +
                                                        is-anegative regulation of insulin-like growth factor receptor signaling pathway
                                                        is-anegative regulation of integrin-mediated signaling pathway
                                                        is-anegative regulation of intracellular signal transduction +
                                                        is-anegative regulation of intracellular steroid hormone receptor signaling pathway +
                                                        is-anegative regulation of lipopolysaccharide-mediated signaling pathway +
                                                        is-anegative regulation of nerve growth factor receptor activity
                                                        is-anegative regulation of netrin-activated signaling pathway
                                                        is-anegative regulation of neuronal signal transduction
                                                        is-anegative regulation of neurotrophin TRK receptor signaling pathway
                                                        is-anegative regulation of Notch signaling pathway +
                                                        is-anegative regulation of peptidoglycan recognition protein signaling pathway
                                                        is-anegative regulation of peroxisome proliferator activated receptor signaling pathway
                                                        is-anegative regulation of phosphorelay signal transduction system +
                                                        is-anegative regulation of platelet-derived growth factor receptor signaling pathway +
                                                        is-anegative regulation of red or far-red light signaling pathway
                                                        is-anegative regulation of retinoic acid receptor signaling pathway
                                                        is-anegative regulation of Roundabout signaling pathway +
                                                        is-anegative regulation of semaphorin-plexin signaling pathway
                                                        is-anegative regulation of sevenless signaling pathway
                                                        is-anegative regulation of signal transduction by receptor internalization +
                                                        is-anegative regulation of signal transduction in absence of ligand +
                                                        is-anegative regulation of signal transduction in response to host +
                                                        is-anegative regulation of signal transduction involved in conjugation with cellular fusion +
                                                        is-anegative regulation of smoothened signaling pathway +
                                                        is-anegative regulation of sphingolipid mediated signaling pathway
                                                        is-anegative regulation of SREBP signaling pathway +
                                                        is-anegative regulation of thyroid hormone mediated signaling pathway
                                                        is-anegative regulation of Toll signaling pathway
                                                        is-anegative regulation of toll-like receptor signaling pathway +
                                                        is-anegative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                        is-anegative regulation of vascular endothelial growth factor receptor signaling pathway
                                                        is-anegative regulation of vascular endothelial growth factor signaling pathway
                                                        is-anegative regulation of vitamin D receptor signaling pathway
                                                        is-anegative regulation of Wnt signaling pathway +
                                                        is-atermination of signal transduction +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of signaling
                                        is-aregulation of signal transduction
                                                is-aregulation of G-protein coupled receptor protein signaling pathway
                                                        is-across-receptor inhibition within G-protein coupled receptor heterodimer
                                                        is-amodulation by host of symbiont G-protein coupled receptor protein signal transduction +
                                                        is-amodulation by symbiont of host G-protein coupled receptor protein signal transduction +
                                                        is-anegative regulation of G-protein coupled receptor protein signaling pathway [GO:0045744] (61 genes, 82 annotations)
                                                                is-adesensitization of G-protein coupled receptor protein signaling pathway +
                                                                is-aG-protein coupled receptor catabolic process
                                                                is-anegative regulation by host of symbiont G-protein coupled receptor protein signal transduction +
                                                                is-anegative regulation by symbiont of host G-protein coupled receptor protein signal transduction +
                                                                is-anegative regulation of adenosine receptor signaling pathway
                                                                is-anegative regulation of adrenergic receptor signaling pathway +
                                                                is-anegative regulation of dopamine receptor signaling pathway +
                                                                is-anegative regulation of G-protein coupled receptor protein signaling pathway in response to host +
                                                                is-anegative regulation of octopamine or tyramine signaling pathway +
                                                                is-anegative regulation of opioid receptor signaling pathway +
                                                                is-anegative regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion
                                                                is-anegative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway +
                                                                is-anegative regulation of thrombin receptor signaling pathway
                                                                is-atermination of G-protein coupled receptor signaling pathway
                                                        is-apositive regulation of G-protein coupled receptor protein signaling pathway +
                                                        is-aprotein kinase C deactivation
                                                        is-aregulation of adenosine receptor signaling pathway +
                                                        is-aregulation of adrenergic receptor signaling pathway +
                                                        is-aregulation of dopamine receptor signaling pathway +
                                                        is-aregulation of endocannabinoid signaling pathway
                                                        is-aregulation of G-protein coupled receptor protein signaling pathway in response to host +
                                                        is-aregulation of octopamine or tyramine signaling pathway +
                                                        is-aregulation of opioid receptor signaling pathway +
                                                        is-aregulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion +
                                                        is-aregulation of phospholipase C-activating G-protein coupled receptor signaling pathway +
                                                        is-aregulation of proteinase activated receptor activity +
                                                        is-aregulation of rhodopsin mediated signaling pathway +
                                                        is-aregulation of thrombin receptor signaling pathway +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-acellular response to stimulus
                                is-asignal transduction
                                        is-acell surface receptor signaling pathway
                                                is-aG-protein coupled receptor signaling pathway
                                                        is-aadrenergic receptor signaling pathway +
                                                        is-aangiotensin-activated signaling pathway +
                                                        is-aapelin receptor signaling pathway
                                                        is-abombesin receptor signaling pathway
                                                        is-acannabinoid signaling pathway +
                                                        is-acholecystokinin signaling pathway +
                                                        is-acomplement component C5a signaling pathway
                                                        is-adimeric G-protein coupled receptor signaling pathway +
                                                        is-adopamine receptor signaling pathway +
                                                        is-aendothelin receptor signaling pathway +
                                                        is-aepidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway
                                                        is-afollicle-stimulating hormone signaling pathway
                                                        is-aG-protein coupled acetylcholine receptor signaling pathway +
                                                        is-aG-protein coupled glutamate receptor signaling pathway +
                                                        is-aG-protein coupled purinergic receptor signaling pathway +
                                                        is-aG-protein coupled receptor signaling in absence of ligand
                                                        is-aG-protein coupled receptor signaling pathway involved in heart process +
                                                        is-aG-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger +
                                                        is-aG-protein coupled receptor signaling pathway, coupled to S1P second messenger
                                                        is-agamma-aminobutyric acid signaling pathway
                                                        is-agastric inhibitory peptide signaling pathway
                                                        part-ofheterotrimeric G-protein complex cycle
                                                        is-aluteinizing hormone signaling pathway +
                                                        negatively-regulatesnegative regulation of G-protein coupled receptor protein signaling pathway [GO:0045744] (61 genes, 82 annotations)
                                                                is-adesensitization of G-protein coupled receptor protein signaling pathway +
                                                                is-aG-protein coupled receptor catabolic process
                                                                is-anegative regulation by host of symbiont G-protein coupled receptor protein signal transduction +
                                                                is-anegative regulation by symbiont of host G-protein coupled receptor protein signal transduction +
                                                                is-anegative regulation of adenosine receptor signaling pathway
                                                                is-anegative regulation of adrenergic receptor signaling pathway +
                                                                is-anegative regulation of dopamine receptor signaling pathway +
                                                                is-anegative regulation of G-protein coupled receptor protein signaling pathway in response to host +
                                                                is-anegative regulation of octopamine or tyramine signaling pathway +
                                                                is-anegative regulation of opioid receptor signaling pathway +
                                                                is-anegative regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion
                                                                is-anegative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway +
                                                                is-anegative regulation of thrombin receptor signaling pathway
                                                                is-atermination of G-protein coupled receptor signaling pathway
                                                        is-aneuropeptide signaling pathway
                                                        is-aoctopamine or tyramine signaling pathway +
                                                        is-aopioid receptor signaling pathway +
                                                        is-apheromone-dependent signal transduction involved in conjugation with cellular fusion +
                                                        is-aphospholipase C-activating G-protein coupled receptor signaling pathway +
                                                        is-aphospholipase C-inhibiting G-protein coupled receptor signaling pathway
                                                        is-aphospholipase D-activating G-protein coupled receptor signaling pathway
                                                        positively-regulatespositive regulation of G-protein coupled receptor protein signaling pathway +
                                                        is-aprotein kinase C-activating G-protein coupled receptor signaling pathway
                                                        regulatesregulation of G-protein coupled receptor protein signaling pathway +
                                                        is-arhodopsin mediated signaling pathway +
                                                        is-aserotonin receptor signaling pathway +
                                                        is-asignal transduction involved in conjugation with mutual genetic exchange
                                                        is-asomatostatin receptor signaling pathway +
                                                        is-asphingosine-1-phosphate signaling pathway +
                                                        is-atachykinin receptor signaling pathway +
                                                        is-athrombin receptor signaling pathway +
                                                        is-athromboxane A2 signaling pathway
                                                        is-athyroid-stimulating hormone signaling pathway


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-acellular response to stimulus
                                is-asignal transduction
                                        is-acell surface receptor signaling pathway
                                                is-aG-protein coupled receptor signaling pathway
                                                        regulatesregulation of G-protein coupled receptor protein signaling pathway
                                                                is-across-receptor inhibition within G-protein coupled receptor heterodimer
                                                                is-amodulation by host of symbiont G-protein coupled receptor protein signal transduction +
                                                                is-amodulation by symbiont of host G-protein coupled receptor protein signal transduction +
                                                                is-anegative regulation of G-protein coupled receptor protein signaling pathway [GO:0045744] (61 genes, 82 annotations)
                                                                        is-adesensitization of G-protein coupled receptor protein signaling pathway +
                                                                        is-aG-protein coupled receptor catabolic process
                                                                        is-anegative regulation by host of symbiont G-protein coupled receptor protein signal transduction +
                                                                        is-anegative regulation by symbiont of host G-protein coupled receptor protein signal transduction +
                                                                        is-anegative regulation of adenosine receptor signaling pathway
                                                                        is-anegative regulation of adrenergic receptor signaling pathway +
                                                                        is-anegative regulation of dopamine receptor signaling pathway +
                                                                        is-anegative regulation of G-protein coupled receptor protein signaling pathway in response to host +
                                                                        is-anegative regulation of octopamine or tyramine signaling pathway +
                                                                        is-anegative regulation of opioid receptor signaling pathway +
                                                                        is-anegative regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion
                                                                        is-anegative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway +
                                                                        is-anegative regulation of thrombin receptor signaling pathway
                                                                        is-atermination of G-protein coupled receptor signaling pathway
                                                                is-apositive regulation of G-protein coupled receptor protein signaling pathway +
                                                                is-aprotein kinase C deactivation
                                                                is-aregulation of adenosine receptor signaling pathway +
                                                                is-aregulation of adrenergic receptor signaling pathway +
                                                                is-aregulation of dopamine receptor signaling pathway +
                                                                is-aregulation of endocannabinoid signaling pathway
                                                                is-aregulation of G-protein coupled receptor protein signaling pathway in response to host +
                                                                is-aregulation of octopamine or tyramine signaling pathway +
                                                                is-aregulation of opioid receptor signaling pathway +
                                                                is-aregulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion +
                                                                is-aregulation of phospholipase C-activating G-protein coupled receptor signaling pathway +
                                                                is-aregulation of proteinase activated receptor activity +
                                                                is-aregulation of rhodopsin mediated signaling pathway +
                                                                is-aregulation of thrombin receptor signaling pathway +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-acellular response to stimulus
                                is-asignal transduction
                                        negatively-regulatesnegative regulation of signal transduction
                                                is-aextracellular negative regulation of signal transduction +
                                                is-ametarhodopsin inactivation
                                                is-anegative adaptation of signaling pathway +
                                                is-anegative regulation by symbiont of host cAMP-mediated signal transduction +
                                                is-anegative regulation by symbiont of host salicylic acid-mediated defense response +
                                                is-anegative regulation of abscisic acid-activated signaling pathway
                                                is-anegative regulation of anti-Mullerian hormone signaling pathway
                                                is-anegative regulation of antigen receptor-mediated signaling pathway +
                                                is-anegative regulation of apoptotic signaling pathway +
                                                is-anegative regulation of auxin mediated signaling pathway
                                                is-anegative regulation of brain-derived neurotrophic factor receptor signaling pathway +
                                                is-anegative regulation of brassinosteroid mediated signaling pathway
                                                is-anegative regulation of CD40 signaling pathway
                                                is-anegative regulation of cytokine-mediated signaling pathway +
                                                is-anegative regulation of cytokinin-activated signaling pathway
                                                is-anegative regulation of endoplasmic reticulum unfolded protein response
                                                is-anegative regulation of ephrin receptor signaling pathway
                                                is-anegative regulation of ERBB signaling pathway +
                                                is-anegative regulation of Fas signaling pathway
                                                is-anegative regulation of fibroblast growth factor receptor signaling pathway +
                                                is-anegative regulation of G-protein coupled receptor protein signaling pathway [GO:0045744] (61 genes, 82 annotations)
                                                        is-adesensitization of G-protein coupled receptor protein signaling pathway +
                                                        is-aG-protein coupled receptor catabolic process
                                                        is-anegative regulation by host of symbiont G-protein coupled receptor protein signal transduction +
                                                        is-anegative regulation by symbiont of host G-protein coupled receptor protein signal transduction +
                                                        is-anegative regulation of adenosine receptor signaling pathway
                                                        is-anegative regulation of adrenergic receptor signaling pathway +
                                                        is-anegative regulation of dopamine receptor signaling pathway +
                                                        is-anegative regulation of G-protein coupled receptor protein signaling pathway in response to host +
                                                        is-anegative regulation of octopamine or tyramine signaling pathway +
                                                        is-anegative regulation of opioid receptor signaling pathway +
                                                        is-anegative regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion
                                                        is-anegative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway +
                                                        is-anegative regulation of thrombin receptor signaling pathway
                                                        is-atermination of G-protein coupled receptor signaling pathway
                                                is-anegative regulation of gibberellic acid mediated signaling pathway
                                                is-anegative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation
                                                is-anegative regulation of glucocorticoid mediated signaling pathway
                                                is-anegative regulation of glucose mediated signaling pathway
                                                is-anegative regulation of glutamate receptor signaling pathway
                                                is-anegative regulation of growth hormone receptor signaling pathway
                                                is-anegative regulation of hepatocyte growth factor receptor signaling pathway
                                                is-anegative regulation of hypoxia-inducible factor-1alpha signaling pathway
                                                is-anegative regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
                                                is-anegative regulation of insulin receptor signaling pathway +
                                                is-anegative regulation of insulin-like growth factor receptor signaling pathway
                                                is-anegative regulation of integrin-mediated signaling pathway
                                                is-anegative regulation of intracellular signal transduction +
                                                is-anegative regulation of intracellular steroid hormone receptor signaling pathway +
                                                is-anegative regulation of lipopolysaccharide-mediated signaling pathway +
                                                is-anegative regulation of nerve growth factor receptor activity
                                                is-anegative regulation of netrin-activated signaling pathway
                                                is-anegative regulation of neuronal signal transduction
                                                is-anegative regulation of neurotrophin TRK receptor signaling pathway
                                                is-anegative regulation of Notch signaling pathway +
                                                is-anegative regulation of peptidoglycan recognition protein signaling pathway
                                                is-anegative regulation of peroxisome proliferator activated receptor signaling pathway
                                                is-anegative regulation of phosphorelay signal transduction system +
                                                is-anegative regulation of platelet-derived growth factor receptor signaling pathway +
                                                is-anegative regulation of red or far-red light signaling pathway
                                                is-anegative regulation of retinoic acid receptor signaling pathway
                                                is-anegative regulation of Roundabout signaling pathway +
                                                is-anegative regulation of semaphorin-plexin signaling pathway
                                                is-anegative regulation of sevenless signaling pathway
                                                is-anegative regulation of signal transduction by receptor internalization +
                                                is-anegative regulation of signal transduction in absence of ligand +
                                                is-anegative regulation of signal transduction in response to host +
                                                is-anegative regulation of signal transduction involved in conjugation with cellular fusion +
                                                is-anegative regulation of smoothened signaling pathway +
                                                is-anegative regulation of sphingolipid mediated signaling pathway
                                                is-anegative regulation of SREBP signaling pathway +
                                                is-anegative regulation of thyroid hormone mediated signaling pathway
                                                is-anegative regulation of Toll signaling pathway
                                                is-anegative regulation of toll-like receptor signaling pathway +
                                                is-anegative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                is-anegative regulation of vascular endothelial growth factor receptor signaling pathway
                                                is-anegative regulation of vascular endothelial growth factor signaling pathway
                                                is-anegative regulation of vitamin D receptor signaling pathway
                                                is-anegative regulation of Wnt signaling pathway +
                                                is-atermination of signal transduction +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-acellular response to stimulus
                                is-asignal transduction
                                        regulatesregulation of signal transduction
                                                is-anegative regulation of signal transduction
                                                        is-aextracellular negative regulation of signal transduction +
                                                        is-ametarhodopsin inactivation
                                                        is-anegative adaptation of signaling pathway +
                                                        is-anegative regulation by symbiont of host cAMP-mediated signal transduction +
                                                        is-anegative regulation by symbiont of host salicylic acid-mediated defense response +
                                                        is-anegative regulation of abscisic acid-activated signaling pathway
                                                        is-anegative regulation of anti-Mullerian hormone signaling pathway
                                                        is-anegative regulation of antigen receptor-mediated signaling pathway +
                                                        is-anegative regulation of apoptotic signaling pathway +
                                                        is-anegative regulation of auxin mediated signaling pathway
                                                        is-anegative regulation of brain-derived neurotrophic factor receptor signaling pathway +
                                                        is-anegative regulation of brassinosteroid mediated signaling pathway
                                                        is-anegative regulation of CD40 signaling pathway
                                                        is-anegative regulation of cytokine-mediated signaling pathway +
                                                        is-anegative regulation of cytokinin-activated signaling pathway
                                                        is-anegative regulation of endoplasmic reticulum unfolded protein response
                                                        is-anegative regulation of ephrin receptor signaling pathway
                                                        is-anegative regulation of ERBB signaling pathway +
                                                        is-anegative regulation of Fas signaling pathway
                                                        is-anegative regulation of fibroblast growth factor receptor signaling pathway +
                                                        is-anegative regulation of G-protein coupled receptor protein signaling pathway [GO:0045744] (61 genes, 82 annotations)
                                                                is-adesensitization of G-protein coupled receptor protein signaling pathway +
                                                                is-aG-protein coupled receptor catabolic process
                                                                is-anegative regulation by host of symbiont G-protein coupled receptor protein signal transduction +
                                                                is-anegative regulation by symbiont of host G-protein coupled receptor protein signal transduction +
                                                                is-anegative regulation of adenosine receptor signaling pathway
                                                                is-anegative regulation of adrenergic receptor signaling pathway +
                                                                is-anegative regulation of dopamine receptor signaling pathway +
                                                                is-anegative regulation of G-protein coupled receptor protein signaling pathway in response to host +
                                                                is-anegative regulation of octopamine or tyramine signaling pathway +
                                                                is-anegative regulation of opioid receptor signaling pathway +
                                                                is-anegative regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion
                                                                is-anegative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway +
                                                                is-anegative regulation of thrombin receptor signaling pathway
                                                                is-atermination of G-protein coupled receptor signaling pathway
                                                        is-anegative regulation of gibberellic acid mediated signaling pathway
                                                        is-anegative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation
                                                        is-anegative regulation of glucocorticoid mediated signaling pathway
                                                        is-anegative regulation of glucose mediated signaling pathway
                                                        is-anegative regulation of glutamate receptor signaling pathway
                                                        is-anegative regulation of growth hormone receptor signaling pathway
                                                        is-anegative regulation of hepatocyte growth factor receptor signaling pathway
                                                        is-anegative regulation of hypoxia-inducible factor-1alpha signaling pathway
                                                        is-anegative regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
                                                        is-anegative regulation of insulin receptor signaling pathway +
                                                        is-anegative regulation of insulin-like growth factor receptor signaling pathway
                                                        is-anegative regulation of integrin-mediated signaling pathway
                                                        is-anegative regulation of intracellular signal transduction +
                                                        is-anegative regulation of intracellular steroid hormone receptor signaling pathway +
                                                        is-anegative regulation of lipopolysaccharide-mediated signaling pathway +
                                                        is-anegative regulation of nerve growth factor receptor activity
                                                        is-anegative regulation of netrin-activated signaling pathway
                                                        is-anegative regulation of neuronal signal transduction
                                                        is-anegative regulation of neurotrophin TRK receptor signaling pathway
                                                        is-anegative regulation of Notch signaling pathway +
                                                        is-anegative regulation of peptidoglycan recognition protein signaling pathway
                                                        is-anegative regulation of peroxisome proliferator activated receptor signaling pathway
                                                        is-anegative regulation of phosphorelay signal transduction system +
                                                        is-anegative regulation of platelet-derived growth factor receptor signaling pathway +
                                                        is-anegative regulation of red or far-red light signaling pathway
                                                        is-anegative regulation of retinoic acid receptor signaling pathway
                                                        is-anegative regulation of Roundabout signaling pathway +
                                                        is-anegative regulation of semaphorin-plexin signaling pathway
                                                        is-anegative regulation of sevenless signaling pathway
                                                        is-anegative regulation of signal transduction by receptor internalization +
                                                        is-anegative regulation of signal transduction in absence of ligand +
                                                        is-anegative regulation of signal transduction in response to host +
                                                        is-anegative regulation of signal transduction involved in conjugation with cellular fusion +
                                                        is-anegative regulation of smoothened signaling pathway +
                                                        is-anegative regulation of sphingolipid mediated signaling pathway
                                                        is-anegative regulation of SREBP signaling pathway +
                                                        is-anegative regulation of thyroid hormone mediated signaling pathway
                                                        is-anegative regulation of Toll signaling pathway
                                                        is-anegative regulation of toll-like receptor signaling pathway +
                                                        is-anegative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                        is-anegative regulation of vascular endothelial growth factor receptor signaling pathway
                                                        is-anegative regulation of vascular endothelial growth factor signaling pathway
                                                        is-anegative regulation of vitamin D receptor signaling pathway
                                                        is-anegative regulation of Wnt signaling pathway +
                                                        is-atermination of signal transduction +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-acellular response to stimulus
                                is-asignal transduction
                                        regulatesregulation of signal transduction
                                                is-aregulation of G-protein coupled receptor protein signaling pathway
                                                        is-across-receptor inhibition within G-protein coupled receptor heterodimer
                                                        is-amodulation by host of symbiont G-protein coupled receptor protein signal transduction +
                                                        is-amodulation by symbiont of host G-protein coupled receptor protein signal transduction +
                                                        is-anegative regulation of G-protein coupled receptor protein signaling pathway [GO:0045744] (61 genes, 82 annotations)
                                                                is-adesensitization of G-protein coupled receptor protein signaling pathway +
                                                                is-aG-protein coupled receptor catabolic process
                                                                is-anegative regulation by host of symbiont G-protein coupled receptor protein signal transduction +
                                                                is-anegative regulation by symbiont of host G-protein coupled receptor protein signal transduction +
                                                                is-anegative regulation of adenosine receptor signaling pathway
                                                                is-anegative regulation of adrenergic receptor signaling pathway +
                                                                is-anegative regulation of dopamine receptor signaling pathway +
                                                                is-anegative regulation of G-protein coupled receptor protein signaling pathway in response to host +
                                                                is-anegative regulation of octopamine or tyramine signaling pathway +
                                                                is-anegative regulation of opioid receptor signaling pathway +
                                                                is-anegative regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion
                                                                is-anegative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway +
                                                                is-anegative regulation of thrombin receptor signaling pathway
                                                                is-atermination of G-protein coupled receptor signaling pathway
                                                        is-apositive regulation of G-protein coupled receptor protein signaling pathway +
                                                        is-aprotein kinase C deactivation
                                                        is-aregulation of adenosine receptor signaling pathway +
                                                        is-aregulation of adrenergic receptor signaling pathway +
                                                        is-aregulation of dopamine receptor signaling pathway +
                                                        is-aregulation of endocannabinoid signaling pathway
                                                        is-aregulation of G-protein coupled receptor protein signaling pathway in response to host +
                                                        is-aregulation of octopamine or tyramine signaling pathway +
                                                        is-aregulation of opioid receptor signaling pathway +
                                                        is-aregulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion +
                                                        is-aregulation of phospholipase C-activating G-protein coupled receptor signaling pathway +
                                                        is-aregulation of proteinase activated receptor activity +
                                                        is-aregulation of rhodopsin mediated signaling pathway +
                                                        is-aregulation of thrombin receptor signaling pathway +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        negatively-regulatesnegative regulation of cellular process
                                is-anegative regulation of cell communication
                                        is-anegative regulation of signal transduction
                                                is-aextracellular negative regulation of signal transduction +
                                                is-ametarhodopsin inactivation
                                                is-anegative adaptation of signaling pathway +
                                                is-anegative regulation by symbiont of host cAMP-mediated signal transduction +
                                                is-anegative regulation by symbiont of host salicylic acid-mediated defense response +
                                                is-anegative regulation of abscisic acid-activated signaling pathway
                                                is-anegative regulation of anti-Mullerian hormone signaling pathway
                                                is-anegative regulation of antigen receptor-mediated signaling pathway +
                                                is-anegative regulation of apoptotic signaling pathway +
                                                is-anegative regulation of auxin mediated signaling pathway
                                                is-anegative regulation of brain-derived neurotrophic factor receptor signaling pathway +
                                                is-anegative regulation of brassinosteroid mediated signaling pathway
                                                is-anegative regulation of CD40 signaling pathway
                                                is-anegative regulation of cytokine-mediated signaling pathway +
                                                is-anegative regulation of cytokinin-activated signaling pathway
                                                is-anegative regulation of endoplasmic reticulum unfolded protein response
                                                is-anegative regulation of ephrin receptor signaling pathway
                                                is-anegative regulation of ERBB signaling pathway +
                                                is-anegative regulation of Fas signaling pathway
                                                is-anegative regulation of fibroblast growth factor receptor signaling pathway +
                                                is-anegative regulation of G-protein coupled receptor protein signaling pathway [GO:0045744] (61 genes, 82 annotations)
                                                        is-adesensitization of G-protein coupled receptor protein signaling pathway +
                                                        is-aG-protein coupled receptor catabolic process
                                                        is-anegative regulation by host of symbiont G-protein coupled receptor protein signal transduction +
                                                        is-anegative regulation by symbiont of host G-protein coupled receptor protein signal transduction +
                                                        is-anegative regulation of adenosine receptor signaling pathway
                                                        is-anegative regulation of adrenergic receptor signaling pathway +
                                                        is-anegative regulation of dopamine receptor signaling pathway +
                                                        is-anegative regulation of G-protein coupled receptor protein signaling pathway in response to host +
                                                        is-anegative regulation of octopamine or tyramine signaling pathway +
                                                        is-anegative regulation of opioid receptor signaling pathway +
                                                        is-anegative regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion
                                                        is-anegative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway +
                                                        is-anegative regulation of thrombin receptor signaling pathway
                                                        is-atermination of G-protein coupled receptor signaling pathway
                                                is-anegative regulation of gibberellic acid mediated signaling pathway
                                                is-anegative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation
                                                is-anegative regulation of glucocorticoid mediated signaling pathway
                                                is-anegative regulation of glucose mediated signaling pathway
                                                is-anegative regulation of glutamate receptor signaling pathway
                                                is-anegative regulation of growth hormone receptor signaling pathway
                                                is-anegative regulation of hepatocyte growth factor receptor signaling pathway
                                                is-anegative regulation of hypoxia-inducible factor-1alpha signaling pathway
                                                is-anegative regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
                                                is-anegative regulation of insulin receptor signaling pathway +
                                                is-anegative regulation of insulin-like growth factor receptor signaling pathway
                                                is-anegative regulation of integrin-mediated signaling pathway
                                                is-anegative regulation of intracellular signal transduction +
                                                is-anegative regulation of intracellular steroid hormone receptor signaling pathway +
                                                is-anegative regulation of lipopolysaccharide-mediated signaling pathway +
                                                is-anegative regulation of nerve growth factor receptor activity
                                                is-anegative regulation of netrin-activated signaling pathway
                                                is-anegative regulation of neuronal signal transduction
                                                is-anegative regulation of neurotrophin TRK receptor signaling pathway
                                                is-anegative regulation of Notch signaling pathway +
                                                is-anegative regulation of peptidoglycan recognition protein signaling pathway
                                                is-anegative regulation of peroxisome proliferator activated receptor signaling pathway
                                                is-anegative regulation of phosphorelay signal transduction system +
                                                is-anegative regulation of platelet-derived growth factor receptor signaling pathway +
                                                is-anegative regulation of red or far-red light signaling pathway
                                                is-anegative regulation of retinoic acid receptor signaling pathway
                                                is-anegative regulation of Roundabout signaling pathway +
                                                is-anegative regulation of semaphorin-plexin signaling pathway
                                                is-anegative regulation of sevenless signaling pathway
                                                is-anegative regulation of signal transduction by receptor internalization +
                                                is-anegative regulation of signal transduction in absence of ligand +
                                                is-anegative regulation of signal transduction in response to host +
                                                is-anegative regulation of signal transduction involved in conjugation with cellular fusion +
                                                is-anegative regulation of smoothened signaling pathway +
                                                is-anegative regulation of sphingolipid mediated signaling pathway
                                                is-anegative regulation of SREBP signaling pathway +
                                                is-anegative regulation of thyroid hormone mediated signaling pathway
                                                is-anegative regulation of Toll signaling pathway
                                                is-anegative regulation of toll-like receptor signaling pathway +
                                                is-anegative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                is-anegative regulation of vascular endothelial growth factor receptor signaling pathway
                                                is-anegative regulation of vascular endothelial growth factor signaling pathway
                                                is-anegative regulation of vitamin D receptor signaling pathway
                                                is-anegative regulation of Wnt signaling pathway +
                                                is-atermination of signal transduction +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        regulatesregulation of cellular process
                                is-anegative regulation of cellular process
                                        is-anegative regulation of cell communication
                                                is-anegative regulation of signal transduction
                                                        is-aextracellular negative regulation of signal transduction +
                                                        is-ametarhodopsin inactivation
                                                        is-anegative adaptation of signaling pathway +
                                                        is-anegative regulation by symbiont of host cAMP-mediated signal transduction +
                                                        is-anegative regulation by symbiont of host salicylic acid-mediated defense response +
                                                        is-anegative regulation of abscisic acid-activated signaling pathway
                                                        is-anegative regulation of anti-Mullerian hormone signaling pathway
                                                        is-anegative regulation of antigen receptor-mediated signaling pathway +
                                                        is-anegative regulation of apoptotic signaling pathway +
                                                        is-anegative regulation of auxin mediated signaling pathway
                                                        is-anegative regulation of brain-derived neurotrophic factor receptor signaling pathway +
                                                        is-anegative regulation of brassinosteroid mediated signaling pathway
                                                        is-anegative regulation of CD40 signaling pathway
                                                        is-anegative regulation of cytokine-mediated signaling pathway +
                                                        is-anegative regulation of cytokinin-activated signaling pathway
                                                        is-anegative regulation of endoplasmic reticulum unfolded protein response
                                                        is-anegative regulation of ephrin receptor signaling pathway
                                                        is-anegative regulation of ERBB signaling pathway +
                                                        is-anegative regulation of Fas signaling pathway
                                                        is-anegative regulation of fibroblast growth factor receptor signaling pathway +
                                                        is-anegative regulation of G-protein coupled receptor protein signaling pathway [GO:0045744] (61 genes, 82 annotations)
                                                                is-adesensitization of G-protein coupled receptor protein signaling pathway +
                                                                is-aG-protein coupled receptor catabolic process
                                                                is-anegative regulation by host of symbiont G-protein coupled receptor protein signal transduction +
                                                                is-anegative regulation by symbiont of host G-protein coupled receptor protein signal transduction +
                                                                is-anegative regulation of adenosine receptor signaling pathway
                                                                is-anegative regulation of adrenergic receptor signaling pathway +
                                                                is-anegative regulation of dopamine receptor signaling pathway +
                                                                is-anegative regulation of G-protein coupled receptor protein signaling pathway in response to host +
                                                                is-anegative regulation of octopamine or tyramine signaling pathway +
                                                                is-anegative regulation of opioid receptor signaling pathway +
                                                                is-anegative regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion
                                                                is-anegative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway +
                                                                is-anegative regulation of thrombin receptor signaling pathway
                                                                is-atermination of G-protein coupled receptor signaling pathway
                                                        is-anegative regulation of gibberellic acid mediated signaling pathway
                                                        is-anegative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation
                                                        is-anegative regulation of glucocorticoid mediated signaling pathway
                                                        is-anegative regulation of glucose mediated signaling pathway
                                                        is-anegative regulation of glutamate receptor signaling pathway
                                                        is-anegative regulation of growth hormone receptor signaling pathway
                                                        is-anegative regulation of hepatocyte growth factor receptor signaling pathway
                                                        is-anegative regulation of hypoxia-inducible factor-1alpha signaling pathway
                                                        is-anegative regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
                                                        is-anegative regulation of insulin receptor signaling pathway +
                                                        is-anegative regulation of insulin-like growth factor receptor signaling pathway
                                                        is-anegative regulation of integrin-mediated signaling pathway
                                                        is-anegative regulation of intracellular signal transduction +
                                                        is-anegative regulation of intracellular steroid hormone receptor signaling pathway +
                                                        is-anegative regulation of lipopolysaccharide-mediated signaling pathway +
                                                        is-anegative regulation of nerve growth factor receptor activity
                                                        is-anegative regulation of netrin-activated signaling pathway
                                                        is-anegative regulation of neuronal signal transduction
                                                        is-anegative regulation of neurotrophin TRK receptor signaling pathway
                                                        is-anegative regulation of Notch signaling pathway +
                                                        is-anegative regulation of peptidoglycan recognition protein signaling pathway
                                                        is-anegative regulation of peroxisome proliferator activated receptor signaling pathway
                                                        is-anegative regulation of phosphorelay signal transduction system +
                                                        is-anegative regulation of platelet-derived growth factor receptor signaling pathway +
                                                        is-anegative regulation of red or far-red light signaling pathway
                                                        is-anegative regulation of retinoic acid receptor signaling pathway
                                                        is-anegative regulation of Roundabout signaling pathway +
                                                        is-anegative regulation of semaphorin-plexin signaling pathway
                                                        is-anegative regulation of sevenless signaling pathway
                                                        is-anegative regulation of signal transduction by receptor internalization +
                                                        is-anegative regulation of signal transduction in absence of ligand +
                                                        is-anegative regulation of signal transduction in response to host +
                                                        is-anegative regulation of signal transduction involved in conjugation with cellular fusion +
                                                        is-anegative regulation of smoothened signaling pathway +
                                                        is-anegative regulation of sphingolipid mediated signaling pathway
                                                        is-anegative regulation of SREBP signaling pathway +