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Gene Ontology Browser
Term Detail
GO term:bone resorption
GO id:GO:0045453
Definition:The process in which specialized cells known as osteoclasts degrade the organic and inorganic portions of bone, and endocytose and transport the degradation products.
Number of paths to term: 6

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological quality
                                is-ahomeostatic process
                                        is-aanatomical structure homeostasis
                                                is-atissue homeostasis
                                                        is-aamnioserosa maintenance
                                                        is-abone resorption [GO:0045453] (55 genes, 62 annotations)
                                                                negatively-regulatesnegative regulation of bone resorption
                                                                positively-regulatespositive regulation of bone resorption
                                                                regulatesregulation of bone resorption +
                                                        is-acartilage homeostasis +
                                                        is-achemical homeostasis within a tissue +
                                                        is-acompartment boundary maintenance
                                                        is-aepithelial structure maintenance +
                                                        is-ahomeostasis of number of cells within a tissue +
                                                        is-amaintenance of lens transparency +
                                                        is-aretina homeostasis +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological quality
                                is-ahomeostatic process
                                        is-amulticellular organismal homeostasis
                                                part-oftissue homeostasis
                                                        is-aamnioserosa maintenance
                                                        is-abone resorption [GO:0045453] (55 genes, 62 annotations)
                                                                negatively-regulatesnegative regulation of bone resorption
                                                                positively-regulatespositive regulation of bone resorption
                                                                regulatesregulation of bone resorption +
                                                        is-acartilage homeostasis +
                                                        is-achemical homeostasis within a tissue +
                                                        is-acompartment boundary maintenance
                                                        is-aepithelial structure maintenance +
                                                        is-ahomeostasis of number of cells within a tissue +
                                                        is-amaintenance of lens transparency +
                                                        is-aretina homeostasis +


Gene_Ontology
        is-abiological_process
                is-amulticellular organismal process
                        is-asingle-multicellular organism process
                                is-amulticellular organismal homeostasis
                                        part-oftissue homeostasis
                                                is-aamnioserosa maintenance
                                                is-abone resorption [GO:0045453] (55 genes, 62 annotations)
                                                        negatively-regulatesnegative regulation of bone resorption
                                                        positively-regulatespositive regulation of bone resorption
                                                        regulatesregulation of bone resorption +
                                                is-acartilage homeostasis +
                                                is-achemical homeostasis within a tissue +
                                                is-acompartment boundary maintenance
                                                is-aepithelial structure maintenance +
                                                is-ahomeostasis of number of cells within a tissue +
                                                is-amaintenance of lens transparency +
                                                is-aretina homeostasis +


Gene_Ontology
        is-abiological_process
                is-amulticellular organismal process
                        is-asingle-multicellular organism process
                                is-atissue remodeling
                                        is-abone remodeling
                                                part-ofbone resorption [GO:0045453] (55 genes, 62 annotations)
                                                        negatively-regulatesnegative regulation of bone resorption
                                                        positively-regulatespositive regulation of bone resorption
                                                        regulatesregulation of bone resorption +
                                                negatively-regulatesnegative regulation of bone remodeling +
                                                part-ofossification involved in bone remodeling
                                                positively-regulatespositive regulation of bone remodeling +
                                                regulatesregulation of bone remodeling +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-multicellular organism process
                                is-amulticellular organismal homeostasis
                                        part-oftissue homeostasis
                                                is-aamnioserosa maintenance
                                                is-abone resorption [GO:0045453] (55 genes, 62 annotations)
                                                        negatively-regulatesnegative regulation of bone resorption
                                                        positively-regulatespositive regulation of bone resorption
                                                        regulatesregulation of bone resorption +
                                                is-acartilage homeostasis +
                                                is-achemical homeostasis within a tissue +
                                                is-acompartment boundary maintenance
                                                is-aepithelial structure maintenance +
                                                is-ahomeostasis of number of cells within a tissue +
                                                is-amaintenance of lens transparency +
                                                is-aretina homeostasis +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-multicellular organism process
                                is-atissue remodeling
                                        is-abone remodeling
                                                part-ofbone resorption [GO:0045453] (55 genes, 62 annotations)
                                                        negatively-regulatesnegative regulation of bone resorption
                                                        positively-regulatespositive regulation of bone resorption
                                                        regulatesregulation of bone resorption +
                                                negatively-regulatesnegative regulation of bone remodeling +
                                                part-ofossification involved in bone remodeling
                                                positively-regulatespositive regulation of bone remodeling +
                                                regulatesregulation of bone remodeling +


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory