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Gene Ontology Browser
Term Detail
GO term:macropinocytosis
Synonym: clathrin-independent pinocytosis
GO id:GO:0044351
Definition:An endocytosis process that results in the uptake of liquid material by cells from their external environment by the 'ruffling' of the cell membrane to form heterogeneously sized intracellular vesicles called macropinosomes, which can be up to 5 micrometers in size.
Number of paths to term: 1

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-abiological_process
                is-alocalization
                        is-aestablishment of localization
                                is-atransport
                                        is-avesicle-mediated transport
                                                is-aendocytosis
                                                        is-apinocytosis
                                                                is-amacropinocytosis [GO:0044351] (5 genes, 5 annotations)
                                                                        is-amulti-organism macropinocytosis +
                                                                        is-asingle-organism macropinocytosis
                                                                is-amicropinocytosis +
                                                                is-amulti-organism pinocytosis +
                                                                negatively-regulatesnegative regulation of pinocytosis
                                                                positively-regulatespositive regulation of pinocytosis
                                                                regulatesregulation of pinocytosis +
                                                                is-asingle-organism pinocytosis +


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory