About   Help   FAQ
Gene Ontology Browser
Term Detail
GO term:macropinocytosis
Synonym: clathrin-independent pinocytosis
GO id:GO:0044351
Definition:An endocytosis process that results in the uptake of liquid material by cells from their external environment by the 'ruffling' of the cell membrane to form heterogeneously sized intracellular vesicles called macropinosomes, which can be up to 5 micrometers in size.
Number of paths to term: 1

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship

                        is-aestablishment of localization
                                        is-avesicle-mediated transport
                                                                is-amacropinocytosis [GO:0044351] (7 genes, 7 annotations)
                                                                        is-amulti-organism macropinocytosis +
                                                                        negatively-regulatesnegative regulation of macropinocytosis
                                                                        positively-regulatespositive regulation of macropinocytosis
                                                                        regulatesregulation of macropinocytosis +
                                                                        is-asingle-organism macropinocytosis +
                                                                is-amicropinocytosis +
                                                                is-amulti-organism pinocytosis +
                                                                negatively-regulatesnegative regulation of pinocytosis +
                                                                positively-regulatespositive regulation of pinocytosis +
                                                                regulatesregulation of pinocytosis +
                                                                is-asingle-organism pinocytosis +

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
MGI 6.08
The Jackson Laboratory