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Gene Ontology Browser
Term Detail
GO term:histone deacetylase activity (H4-K16 specific)
GO id:GO:0034739
Definition:Catalysis of the reaction: histone H4 N6-acetyl-L-lysine (position 16) + H2O = histone H4 L-lysine (position 16) + acetate. This reaction represents the removal of an acetyl group from lysine at position 16 of the histone H4 protein.
Number of paths to term: 2

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-amolecular_function
                is-acatalytic activity
                        is-ahydrolase activity
                                is-adeacetylase activity
                                        is-aprotein deacetylase activity
                                                is-ahistone deacetylase activity
                                                        is-ahistone deacetylase activity (H3-K14 specific) +
                                                        is-ahistone deacetylase activity (H3-K4 specific)
                                                        is-ahistone deacetylase activity (H3-K9 specific) +
                                                        is-ahistone deacetylase activity (H4-K16 specific) [GO:0034739] (13 genes, 35 annotations)
                                                                is-aNAD-dependent histone deacetylase activity (H3-K18 specific)
                                                                is-aNAD-dependent histone deacetylase activity (H4-K16 specific)
                                                        is-aNAD-dependent histone deacetylase activity +
                                                        is-aNAD-independent histone deacetylase activity


Gene_Ontology
        is-amolecular_function
                is-acatalytic activity
                        is-ahydrolase activity
                                is-ahydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
                                        is-ahydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
                                                is-ahistone deacetylase activity
                                                        is-ahistone deacetylase activity (H3-K14 specific) +
                                                        is-ahistone deacetylase activity (H3-K4 specific)
                                                        is-ahistone deacetylase activity (H3-K9 specific) +
                                                        is-ahistone deacetylase activity (H4-K16 specific) [GO:0034739] (13 genes, 35 annotations)
                                                                is-aNAD-dependent histone deacetylase activity (H3-K18 specific)
                                                                is-aNAD-dependent histone deacetylase activity (H4-K16 specific)
                                                        is-aNAD-dependent histone deacetylase activity +
                                                        is-aNAD-independent histone deacetylase activity


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory