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Gene Ontology Browser
Term Detail
GO term:ubiquitin-ubiquitin ligase activity
Synonym: E4
GO id:GO:0034450
Definition:Isoenergetic transfer of ubiquitin from one protein to an existing ubiquitin chain via the reaction X-ubiquitin + Y-ubiquitin -> Y-ubiquitin-ubiquitin + X, where both the X-ubiquitin and Y-ubiquitin-ubiquitin linkages are thioester bonds between the C-terminal glycine of ubiquitin and a sulfhydryl side group of a cysteine residue.
Number of paths to term: 1

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship

                is-acatalytic activity
                        is-atransferase activity
                                is-aubiquitin-protein transferase activity
                                        is-aubiquitin protein ligase activity
                                                is-aubiquitin-ubiquitin ligase activity [GO:0034450] (8 genes, 8 annotations)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 5.19
The Jackson Laboratory