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Gene Ontology Browser
Term Detail
GO term:MHC class II receptor activity
Synonym: alpha-beta T cell receptor activity
Synonym: gamma-delta T cell receptor activity
Synonym: T cell receptor activity
GO id:GO:0032395
Definition:Combining with an MHC class II protein complex and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
CommentsNote that this term is intended for annotation of gene products that act as receptors for MHC class II protein complexes, not for components of the MHC class II protein complexes themselves.
Number of paths to term: 2

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-amolecular_function
                is-amolecular transducer activity
                        is-asignal transducer activity
                                is-asignaling receptor activity
                                        is-atransmembrane signaling receptor activity
                                                is-aacetylcholine receptor activity +
                                                is-aapolipoprotein A-I receptor activity
                                                is-aaxon guidance receptor activity
                                                is-acollagen receptor activity +
                                                is-acomplement receptor activity +
                                                is-acytokine receptor activity +
                                                is-acytokinin receptor activity +
                                                is-adeath receptor activity +
                                                is-aG-protein coupled receptor activity +
                                                is-aGABA receptor activity +
                                                is-aglutamate receptor activity +
                                                is-ahedgehog receptor activity
                                                is-aICAM-3 receptor activity
                                                is-aimmunoglobulin receptor activity +
                                                is-alatrotoxin receptor activity
                                                is-aMHC class I receptor activity +
                                                is-aMHC class Ib receptor activity
                                                is-aMHC class II receptor activity [GO:0032395] (1 genes, 1 annotations)
                                                is-anetrin receptor activity +
                                                is-aneuregulin receptor activity
                                                is-aneurotensin receptor activity, non-G-protein coupled
                                                is-anon-tyrosine kinase fibroblast growth factor receptor activity
                                                is-anucleotide receptor activity +
                                                is-aolfactory receptor activity +
                                                is-aopsonin receptor activity +
                                                is-aosmosensor activity
                                                is-apurinergic receptor activity +
                                                is-areelin receptor activity
                                                is-asemaphorin receptor activity
                                                is-asulfonylurea receptor activity
                                                is-atiggrin receptor activity
                                                is-atransmembrane receptor protein kinase activity +
                                                is-atransmembrane receptor protein phosphatase activity +
                                                is-aWnt-activated receptor activity


Gene_Ontology
        is-amolecular_function
                is-areceptor activity
                        is-asignaling receptor activity
                                is-atransmembrane signaling receptor activity
                                        is-aacetylcholine receptor activity +
                                        is-aapolipoprotein A-I receptor activity
                                        is-aaxon guidance receptor activity
                                        is-acollagen receptor activity +
                                        is-acomplement receptor activity +
                                        is-acytokine receptor activity +
                                        is-acytokinin receptor activity +
                                        is-adeath receptor activity +
                                        is-aG-protein coupled receptor activity +
                                        is-aGABA receptor activity +
                                        is-aglutamate receptor activity +
                                        is-ahedgehog receptor activity
                                        is-aICAM-3 receptor activity
                                        is-aimmunoglobulin receptor activity +
                                        is-alatrotoxin receptor activity
                                        is-aMHC class I receptor activity +
                                        is-aMHC class Ib receptor activity
                                        is-aMHC class II receptor activity [GO:0032395] (1 genes, 1 annotations)
                                        is-anetrin receptor activity +
                                        is-aneuregulin receptor activity
                                        is-aneurotensin receptor activity, non-G-protein coupled
                                        is-anon-tyrosine kinase fibroblast growth factor receptor activity
                                        is-anucleotide receptor activity +
                                        is-aolfactory receptor activity +
                                        is-aopsonin receptor activity +
                                        is-aosmosensor activity
                                        is-apurinergic receptor activity +
                                        is-areelin receptor activity
                                        is-asemaphorin receptor activity
                                        is-asulfonylurea receptor activity
                                        is-atiggrin receptor activity
                                        is-atransmembrane receptor protein kinase activity +
                                        is-atransmembrane receptor protein phosphatase activity +
                                        is-aWnt-activated receptor activity


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory