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Gene Ontology Browser
Term Detail
GO term:cyclin-dependent protein kinase activating kinase activity
Synonym: CAK
Synonym: cdk-activating kinase activity
Synonym: cyclin-dependent protein kinase activating kinase, intrinsic catalyst activity
GO id:GO:0019912
Definition:Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein; increases the activity of a cyclin-dependent protein kinase (CDK).
Number of paths to term: 5

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-amolecular_function
                is-acatalytic activity
                        is-atransferase activity
                                is-atransferase activity, transferring phosphorus-containing groups
                                        is-akinase activity
                                                is-aprotein kinase activity
                                                        is-a[3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase activity
                                                        is-a[acetyl-CoA carboxylase] kinase activity
                                                        is-a[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity
                                                        is-a[isocitrate dehydrogenase (NADP+)] kinase activity
                                                        is-a[tyrosine 3-monooxygenase] kinase activity
                                                        is-abeta-adrenergic receptor kinase activity
                                                        is-acalcium-dependent protein kinase activity +
                                                        is-acaldesmon kinase activity
                                                        is-acyclin-dependent protein kinase activating kinase activity [GO:0019912] (9 genes, 9 annotations)
                                                        is-acyclin-dependent protein kinase activity +
                                                        is-adephospho-[reductase kinase] kinase activity
                                                        is-ahistone kinase activity +
                                                        is-alow-density-lipoprotein particle receptor kinase activity
                                                        is-aprotein arginine kinase activity
                                                        is-aprotein histidine kinase activity +
                                                        is-aprotein kinase activity involved in regulation of protein localization to cell division site involved in cytokinesis
                                                        is-aprotein serine/threonine kinase activity +
                                                        is-aprotein serine/threonine/tyrosine kinase activity +
                                                        is-aprotein tyrosine kinase activity +
                                                        is-apyruvate dehydrogenase (acetyl-transferring) kinase activity
                                                        is-arhodopsin kinase activity
                                                        is-atau-protein kinase activity
                                                        is-atransmembrane receptor protein kinase activity +
                                                        is-atropomyosin kinase activity


Gene_Ontology
        is-amolecular_function
                is-acatalytic activity
                        is-atransferase activity
                                is-atransferase activity, transferring phosphorus-containing groups
                                        is-aphosphotransferase activity, alcohol group as acceptor
                                                is-aprotein kinase activity
                                                        is-a[3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase activity
                                                        is-a[acetyl-CoA carboxylase] kinase activity
                                                        is-a[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity
                                                        is-a[isocitrate dehydrogenase (NADP+)] kinase activity
                                                        is-a[tyrosine 3-monooxygenase] kinase activity
                                                        is-abeta-adrenergic receptor kinase activity
                                                        is-acalcium-dependent protein kinase activity +
                                                        is-acaldesmon kinase activity
                                                        is-acyclin-dependent protein kinase activating kinase activity [GO:0019912] (9 genes, 9 annotations)
                                                        is-acyclin-dependent protein kinase activity +
                                                        is-adephospho-[reductase kinase] kinase activity
                                                        is-ahistone kinase activity +
                                                        is-alow-density-lipoprotein particle receptor kinase activity
                                                        is-aprotein arginine kinase activity
                                                        is-aprotein histidine kinase activity +
                                                        is-aprotein kinase activity involved in regulation of protein localization to cell division site involved in cytokinesis
                                                        is-aprotein serine/threonine kinase activity +
                                                        is-aprotein serine/threonine/tyrosine kinase activity +
                                                        is-aprotein tyrosine kinase activity +
                                                        is-apyruvate dehydrogenase (acetyl-transferring) kinase activity
                                                        is-arhodopsin kinase activity
                                                        is-atau-protein kinase activity
                                                        is-atransmembrane receptor protein kinase activity +
                                                        is-atropomyosin kinase activity


Gene_Ontology
        is-amolecular_function
                is-aenzyme regulator activity
                        is-aenzyme activator activity
                                is-akinase activator activity
                                        is-aprotein kinase activator activity
                                                is-acyclin-dependent protein kinase activating kinase activity [GO:0019912] (9 genes, 9 annotations)
                                                is-aeukaryotic elongation factor-2 kinase activator activity
                                                is-aprotein serine/threonine kinase activator activity +
                                                is-aprotein tyrosine kinase activator activity +


Gene_Ontology
        is-amolecular_function
                is-aenzyme regulator activity
                        is-akinase regulator activity
                                is-akinase activator activity
                                        is-aprotein kinase activator activity
                                                is-acyclin-dependent protein kinase activating kinase activity [GO:0019912] (9 genes, 9 annotations)
                                                is-aeukaryotic elongation factor-2 kinase activator activity
                                                is-aprotein serine/threonine kinase activator activity +
                                                is-aprotein tyrosine kinase activator activity +


Gene_Ontology
        is-amolecular_function
                is-aenzyme regulator activity
                        is-akinase regulator activity
                                is-aprotein kinase regulator activity
                                        is-aprotein kinase activator activity
                                                is-acyclin-dependent protein kinase activating kinase activity [GO:0019912] (9 genes, 9 annotations)
                                                is-aeukaryotic elongation factor-2 kinase activator activity
                                                is-aprotein serine/threonine kinase activator activity +
                                                is-aprotein tyrosine kinase activator activity +


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory