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Gene Ontology Browser
Term Detail
GO term:lipoate synthase activity
Synonym: LipA
Synonym: lipoic acid synthase
Synonym: lipoyl synthase activity
Synonym: LS
Synonym: protein 6-N-(octanoyl)lysine:sulfur sulfurtransferase activity
Synonym: protein N6-(octanoyl)lysine:sulfur sulfurtransferase activity
GO id:GO:0016992
Definition:Catalysis of the reaction: protein N6-(octanoyl)lysine + 2 sulfur + 2 S-adenosyl-L-methionine = protein N6-(lipoyl)lysine + 2 L-methionine + 2 5'-deoxyadenosyl.
Number of paths to term: 3

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-amolecular_function
                is-acatalytic activity
                        is-aligase activity
                                is-aligase activity, forming carbon-nitrogen bonds
                                        is-alipoate-protein ligase activity
                                                is-alipoate synthase activity [GO:0016992] (1 genes, 1 annotations)


Gene_Ontology
        is-amolecular_function
                is-acatalytic activity
                        is-aradical SAM enzyme activity
                                is-a4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase activity
                                is-a[formate-C-acetyltransferase]-activating enzyme activity
                                is-abiotin synthase activity
                                is-aglycerol dehydratase activity
                                is-alipoate synthase activity [GO:0016992] (1 genes, 1 annotations)
                                is-alysine 2,3-aminomutase activity


Gene_Ontology
        is-amolecular_function
                is-acatalytic activity
                        is-atransferase activity
                                is-atransferase activity, transferring sulfur-containing groups
                                        is-asulfurtransferase activity
                                                is-a3-mercaptopyruvate sulfurtransferase activity
                                                is-abiotin synthase activity
                                                is-acysteine desulfurase activity
                                                is-alipoate synthase activity [GO:0016992] (1 genes, 1 annotations)
                                                is-amolybdopterin synthase activity
                                                is-amolybdopterin-synthase sulfurtransferase activity
                                                is-athiazole synthase activity
                                                is-athiosulfate sulfurtransferase activity
                                                is-athiosulfate-dithiol sulfurtransferase activity
                                                is-athiosulfate-thiol sulfurtransferase activity


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/21/2014
MGI 5.20
The Jackson Laboratory