| GO term: | extracellular-glycine-gated chloride channel activity |
| Synonym: | glycine-inhibited chloride channel activity |
| Synonym: | glycine receptor |
| GO id: | GO:0016934 |
| Definition: | Catalysis of the transmembrane transfer of a chloride ion by a channel that opens when extracellular glycine has been bound by the channel complex or one of its constituent parts. |
| Comments | Note that this term represents an activity and not a gene product. Consider also annotating to the molecular function term 'receptor activity ; GO:0004872'. |
| Number of paths to term: | 27 |
denotes an 'is-a' relationship
denotes a 'part-of' relationship
denotes a 'regulates' relationship
denotes a 'positively-regulates' relationship
denotes a 'negatively-regulates' relationship
molecular_functiontransporter activitysubstrate-specific transporter activitysubstrate-specific transmembrane transporter activityion transmembrane transporter activityanion transmembrane transporter activityanion channel activitychloride channel activityATP-binding and phosphorylation-dependent chloride channel activitychannel-conductance-controlling ATPase activityextracellular-glutamate-gated chloride channel activityextracellular-glycine-gated chloride channel activity [GO:0016934] (5 genes, 10 annotations)histamine-gated chloride channel activityintracellular calcium activated chloride channel activityvoltage-gated chloride channel activity +volume-sensitive chloride channel activitymolecular_functiontransporter activitysubstrate-specific transporter activitysubstrate-specific transmembrane transporter activityion transmembrane transporter activityanion transmembrane transporter activityinorganic anion transmembrane transporter activitychloride transmembrane transporter activitychloride channel activityATP-binding and phosphorylation-dependent chloride channel activitychannel-conductance-controlling ATPase activityextracellular-glutamate-gated chloride channel activityextracellular-glycine-gated chloride channel activity [GO:0016934] (5 genes, 10 annotations)histamine-gated chloride channel activityintracellular calcium activated chloride channel activityvoltage-gated chloride channel activity +volume-sensitive chloride channel activitymolecular_functiontransporter activitysubstrate-specific transporter activitysubstrate-specific transmembrane transporter activityion transmembrane transporter activityion channel activityanion channel activitychloride channel activityATP-binding and phosphorylation-dependent chloride channel activitychannel-conductance-controlling ATPase activityextracellular-glutamate-gated chloride channel activityextracellular-glycine-gated chloride channel activity [GO:0016934] (5 genes, 10 annotations)histamine-gated chloride channel activityintracellular calcium activated chloride channel activityvoltage-gated chloride channel activity +volume-sensitive chloride channel activitymolecular_functiontransporter activitysubstrate-specific transporter activitysubstrate-specific transmembrane transporter activityion transmembrane transporter activityion channel activityligand-gated ion channel activityextracellular ligand-gated ion channel activityexcitatory extracellular ligand-gated ion channel activityextracellular-glycine-gated ion channel activityextracellular-glycine-gated chloride channel activity [GO:0016934] (5 genes, 10 annotations)molecular_functiontransporter activitysubstrate-specific transporter activitysubstrate-specific transmembrane transporter activityion transmembrane transporter activityion channel activityligand-gated ion channel activityextracellular ligand-gated ion channel activityinhibitory extracellular ligand-gated ion channel activityextracellular-glycine-gated chloride channel activity [GO:0016934] (5 genes, 10 annotations)molecular_functiontransporter activitysubstrate-specific transporter activitysubstrate-specific transmembrane transporter activityion transmembrane transporter activityion gated channel activityligand-gated ion channel activityextracellular ligand-gated ion channel activityexcitatory extracellular ligand-gated ion channel activityextracellular-glycine-gated ion channel activityextracellular-glycine-gated chloride channel activity [GO:0016934] (5 genes, 10 annotations)molecular_functiontransporter activitysubstrate-specific transporter activitysubstrate-specific transmembrane transporter activityion transmembrane transporter activityion gated channel activityligand-gated ion channel activityextracellular ligand-gated ion channel activityinhibitory extracellular ligand-gated ion channel activityextracellular-glycine-gated chloride channel activity [GO:0016934] (5 genes, 10 annotations)molecular_functiontransporter activitysubstrate-specific transporter activitysubstrate-specific transmembrane transporter activitysubstrate-specific channel activityion channel activityanion channel activitychloride channel activityATP-binding and phosphorylation-dependent chloride channel activitychannel-conductance-controlling ATPase activityextracellular-glutamate-gated chloride channel activityextracellular-glycine-gated chloride channel activity [GO:0016934] (5 genes, 10 annotations)histamine-gated chloride channel activityintracellular calcium activated chloride channel activityvoltage-gated chloride channel activity +volume-sensitive chloride channel activitymolecular_functiontransporter activitysubstrate-specific transporter activitysubstrate-specific transmembrane transporter activitysubstrate-specific channel activityion channel activityligand-gated ion channel activityextracellular ligand-gated ion channel activityexcitatory extracellular ligand-gated ion channel activityextracellular-glycine-gated ion channel activityextracellular-glycine-gated chloride channel activity [GO:0016934] (5 genes, 10 annotations)molecular_functiontransporter activitysubstrate-specific transporter activitysubstrate-specific transmembrane transporter activitysubstrate-specific channel activityion channel activityligand-gated ion channel activityextracellular ligand-gated ion channel activityinhibitory extracellular ligand-gated ion channel activityextracellular-glycine-gated chloride channel activity [GO:0016934] (5 genes, 10 annotations)molecular_functiontransporter activitytransmembrane transporter activitypassive transmembrane transporter activitychannel activitygated channel activityion gated channel activityligand-gated ion channel activityextracellular ligand-gated ion channel activityexcitatory extracellular ligand-gated ion channel activityextracellular-glycine-gated ion channel activityextracellular-glycine-gated chloride channel activity [GO:0016934] (5 genes, 10 annotations)molecular_functiontransporter activitytransmembrane transporter activitypassive transmembrane transporter activitychannel activitygated channel activityion gated channel activityligand-gated ion channel activityextracellular ligand-gated ion channel activityinhibitory extracellular ligand-gated ion channel activityextracellular-glycine-gated chloride channel activity [GO:0016934] (5 genes, 10 annotations)molecular_functiontransporter activitytransmembrane transporter activitypassive transmembrane transporter activitychannel activitygated channel activityligand-gated channel activityligand-gated ion channel activityextracellular ligand-gated ion channel activityexcitatory extracellular ligand-gated ion channel activityextracellular-glycine-gated ion channel activityextracellular-glycine-gated chloride channel activity [GO:0016934] (5 genes, 10 annotations)molecular_functiontransporter activitytransmembrane transporter activitypassive transmembrane transporter activitychannel activitygated channel activityligand-gated channel activityligand-gated ion channel activityextracellular ligand-gated ion channel activityinhibitory extracellular ligand-gated ion channel activityextracellular-glycine-gated chloride channel activity [GO:0016934] (5 genes, 10 annotations)molecular_functiontransporter activitytransmembrane transporter activitypassive transmembrane transporter activitychannel activitysubstrate-specific channel activityion channel activityanion channel activitychloride channel activityATP-binding and phosphorylation-dependent chloride channel activitychannel-conductance-controlling ATPase activityextracellular-glutamate-gated chloride channel activityextracellular-glycine-gated chloride channel activity [GO:0016934] (5 genes, 10 annotations)histamine-gated chloride channel activityintracellular calcium activated chloride channel activityvoltage-gated chloride channel activity +volume-sensitive chloride channel activitymolecular_functiontransporter activitytransmembrane transporter activitypassive transmembrane transporter activitychannel activitysubstrate-specific channel activityion channel activityligand-gated ion channel activityextracellular ligand-gated ion channel activityexcitatory extracellular ligand-gated ion channel activityextracellular-glycine-gated ion channel activityextracellular-glycine-gated chloride channel activity [GO:0016934] (5 genes, 10 annotations)molecular_functiontransporter activitytransmembrane transporter activitypassive transmembrane transporter activitychannel activitysubstrate-specific channel activityion channel activityligand-gated ion channel activityextracellular ligand-gated ion channel activityinhibitory extracellular ligand-gated ion channel activityextracellular-glycine-gated chloride channel activity [GO:0016934] (5 genes, 10 annotations)molecular_functiontransporter activitytransmembrane transporter activitysubstrate-specific transmembrane transporter activityion transmembrane transporter activityanion transmembrane transporter activityanion channel activitychloride channel activityATP-binding and phosphorylation-dependent chloride channel activitychannel-conductance-controlling ATPase activityextracellular-glutamate-gated chloride channel activityextracellular-glycine-gated chloride channel activity [GO:0016934] (5 genes, 10 annotations)histamine-gated chloride channel activityintracellular calcium activated chloride channel activityvoltage-gated chloride channel activity +volume-sensitive chloride channel activitymolecular_functiontransporter activitytransmembrane transporter activitysubstrate-specific transmembrane transporter activityion transmembrane transporter activityanion transmembrane transporter activityinorganic anion transmembrane transporter activitychloride transmembrane transporter activitychloride channel activityATP-binding and phosphorylation-dependent chloride channel activitychannel-conductance-controlling ATPase activityextracellular-glutamate-gated chloride channel activityextracellular-glycine-gated chloride channel activity [GO:0016934] (5 genes, 10 annotations)histamine-gated chloride channel activityintracellular calcium activated chloride channel activityvoltage-gated chloride channel activity +volume-sensitive chloride channel activitymolecular_functiontransporter activitytransmembrane transporter activitysubstrate-specific transmembrane transporter activityion transmembrane transporter activityion channel activityanion channel activitychloride channel activityATP-binding and phosphorylation-dependent chloride channel activitychannel-conductance-controlling ATPase activityextracellular-glutamate-gated chloride channel activityextracellular-glycine-gated chloride channel activity [GO:0016934] (5 genes, 10 annotations)histamine-gated chloride channel activityintracellular calcium activated chloride channel activityvoltage-gated chloride channel activity +volume-sensitive chloride channel activitymolecular_functiontransporter activitytransmembrane transporter activitysubstrate-specific transmembrane transporter activityion transmembrane transporter activityion channel activityligand-gated ion channel activityextracellular ligand-gated ion channel activityexcitatory extracellular ligand-gated ion channel activityextracellular-glycine-gated ion channel activityextracellular-glycine-gated chloride channel activity [GO:0016934] (5 genes, 10 annotations)molecular_functiontransporter activitytransmembrane transporter activitysubstrate-specific transmembrane transporter activityion transmembrane transporter activityion channel activityligand-gated ion channel activityextracellular ligand-gated ion channel activityinhibitory extracellular ligand-gated ion channel activityextracellular-glycine-gated chloride channel activity [GO:0016934] (5 genes, 10 annotations)molecular_functiontransporter activitytransmembrane transporter activitysubstrate-specific transmembrane transporter activityion transmembrane transporter activityion gated channel activityligand-gated ion channel activityextracellular ligand-gated ion channel activityexcitatory extracellular ligand-gated ion channel activityextracellular-glycine-gated ion channel activityextracellular-glycine-gated chloride channel activity [GO:0016934] (5 genes, 10 annotations)molecular_functiontransporter activitytransmembrane transporter activitysubstrate-specific transmembrane transporter activityion transmembrane transporter activityion gated channel activityligand-gated ion channel activityextracellular ligand-gated ion channel activityinhibitory extracellular ligand-gated ion channel activityextracellular-glycine-gated chloride channel activity [GO:0016934] (5 genes, 10 annotations)molecular_functiontransporter activitytransmembrane transporter activitysubstrate-specific transmembrane transporter activitysubstrate-specific channel activityion channel activityanion channel activitychloride channel activityATP-binding and phosphorylation-dependent chloride channel activitychannel-conductance-controlling ATPase activityextracellular-glutamate-gated chloride channel activityextracellular-glycine-gated chloride channel activity [GO:0016934] (5 genes, 10 annotations)histamine-gated chloride channel activityintracellular calcium activated chloride channel activityvoltage-gated chloride channel activity +volume-sensitive chloride channel activitymolecular_functiontransporter activitytransmembrane transporter activitysubstrate-specific transmembrane transporter activitysubstrate-specific channel activityion channel activityligand-gated ion channel activityextracellular ligand-gated ion channel activityexcitatory extracellular ligand-gated ion channel activityextracellular-glycine-gated ion channel activityextracellular-glycine-gated chloride channel activity [GO:0016934] (5 genes, 10 annotations)molecular_functiontransporter activitytransmembrane transporter activitysubstrate-specific transmembrane transporter activitysubstrate-specific channel activityion channel activityligand-gated ion channel activityextracellular ligand-gated ion channel activityinhibitory extracellular ligand-gated ion channel activityextracellular-glycine-gated chloride channel activity [GO:0016934] (5 genes, 10 annotations)Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc |
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last database update 05/08/2013 MGI 5.13 |
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