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Gene Ontology Browser
Term Detail
GO term:integral component of membrane
Synonym: integral to membrane
Synonym: transmembrane
GO id:GO:0016021
Definition:The component of a membrane consisting of gene products and protein complexes that have some part that penetrates at least one leaflet of the membrane bilayer. This component includes gene products that are buried in the bilayer with no exposure outside the bilayer.
Number of paths to term: 2

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-acellular_component
                is-amembrane
                        part-ofmembrane part
                                is-aintrinsic component of membrane
                                        is-aanchored component of membrane +
                                        is-aintegral component of membrane [GO:0016021] (5597 genes, 7126 annotations)
                                                part-ofcytochrome o ubiquinol oxidase complex
                                                is-aintegral component of cell outer membrane +
                                                is-aintegral component of organelle membrane +
                                                is-aintegral component of plasma membrane +
                                                is-aintegral component of thylakoid membrane
                                                part-ofion channel complex +
                                                part-oflipopolysaccharide receptor complex
                                                part-ofmeprin A complex
                                                part-ofpore complex +
                                                part-ofsodium ion-transporting two-sector ATPase complex +
                                                is-aspanning component of membrane +
                                                part-oftransmembrane transporter complex +
                                        is-aintrinsic component of cell outer membrane +
                                        is-aintrinsic component of organelle membrane +
                                        is-aintrinsic component of plasma membrane +
                                        is-aintrinsic component of thylakoid membrane +


Gene_Ontology
        is-acellular_component
                is-amembrane part
                        is-aintrinsic component of membrane
                                is-aanchored component of membrane +
                                is-aintegral component of membrane [GO:0016021] (5597 genes, 7126 annotations)
                                        part-ofcytochrome o ubiquinol oxidase complex
                                        is-aintegral component of cell outer membrane +
                                        is-aintegral component of organelle membrane +
                                        is-aintegral component of plasma membrane +
                                        is-aintegral component of thylakoid membrane
                                        part-ofion channel complex +
                                        part-oflipopolysaccharide receptor complex
                                        part-ofmeprin A complex
                                        part-ofpore complex +
                                        part-ofsodium ion-transporting two-sector ATPase complex +
                                        is-aspanning component of membrane +
                                        part-oftransmembrane transporter complex +
                                is-aintrinsic component of cell outer membrane +
                                is-aintrinsic component of organelle membrane +
                                is-aintrinsic component of plasma membrane +
                                is-aintrinsic component of thylakoid membrane +


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory