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Gene Ontology Browser
Term Detail
GO term:integral component of membrane
Synonym: integral to membrane
Synonym: transmembrane
GO id:GO:0016021
Definition:The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
Number of paths to term: 2

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


obsolete Gene_Ontology
        is-acellular_component
                is-amembrane
                        part-ofmembrane part
                                is-aintrinsic component of membrane
                                        is-aanchored component of membrane +
                                        is-aintegral component of membrane [GO:0016021] (5679 genes, 8060 annotations)
                                                part-ofcytochrome o ubiquinol oxidase complex
                                                is-aintegral component of cell outer membrane +
                                                is-aintegral component of organelle membrane +
                                                is-aintegral component of plasma membrane +
                                                is-aintegral component of thylakoid membrane
                                                part-ofion channel complex +
                                                part-oflipopolysaccharide receptor complex
                                                part-ofmeprin A complex
                                                part-ofpore complex +
                                                part-ofsodium ion-transporting two-sector ATPase complex +
                                                is-aspanning component of membrane +
                                                part-oftransmembrane transporter complex +
                                        is-aintrinsic component of cell outer membrane +
                                        is-aintrinsic component of organelle membrane +
                                        is-aintrinsic component of plasma membrane +
                                        is-aintrinsic component of thylakoid membrane +


obsolete Gene_Ontology
        is-acellular_component
                is-amembrane part
                        is-aintrinsic component of membrane
                                is-aanchored component of membrane +
                                is-aintegral component of membrane [GO:0016021] (5679 genes, 8060 annotations)
                                        part-ofcytochrome o ubiquinol oxidase complex
                                        is-aintegral component of cell outer membrane +
                                        is-aintegral component of organelle membrane +
                                        is-aintegral component of plasma membrane +
                                        is-aintegral component of thylakoid membrane
                                        part-ofion channel complex +
                                        part-oflipopolysaccharide receptor complex
                                        part-ofmeprin A complex
                                        part-ofpore complex +
                                        part-ofsodium ion-transporting two-sector ATPase complex +
                                        is-aspanning component of membrane +
                                        part-oftransmembrane transporter complex +
                                is-aintrinsic component of cell outer membrane +
                                is-aintrinsic component of organelle membrane +
                                is-aintrinsic component of plasma membrane +
                                is-aintrinsic component of thylakoid membrane +


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/18/2015
MGI 6.0
The Jackson Laboratory