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Term Detail
GO term:pseudouridine synthase activity
Synonym: transfer ribonucleate pseudouridine synthetase activity
Synonym: transfer RNA pseudouridine synthetase activity
Synonym: tRNA-pseudouridine synthase activity
Synonym: tRNA-pseudouridine synthase I activity
Synonym: tRNA pseudouridylate synthase I activity
Synonym: tRNA-uridine isomerase activity
Synonym: tRNA-uridine uracilmutase activity
GO id:GO:0009982
Alternate id: GO:0016439
Definition:Catalysis of the reaction: RNA uridine = RNA pseudouridine. Conversion of uridine in an RNA molecule to pseudouridine by rotation of the C1'-N-1 glycosidic bond of uridine in RNA to a C1'-C5.
CommentsNote that this term should not be confused with 'pseudouridylate synthase activity ; GO:0004730', which refers to the formation of free pseudouridine from uracil and ribose-5-phosphate.
Number of paths to term: 1

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship

                is-acatalytic activity
                        is-aisomerase activity
                                is-aintramolecular transferase activity
                                        is-a(1,4)-alpha-D-glucan 1-alpha-D-glucosylmutase activity
                                        is-a2-acetolactate mutase activity
                                        is-a2-methyleneglutarate mutase activity
                                        is-a4-carboxymethyl-4-methylbutenolide mutase activity
                                        is-a5-(carboxyamino)imidazole ribonucleotide mutase activity
                                        is-acamelliol C synthase activity
                                        is-achorismate mutase activity
                                        is-aintramolecular transferase activity, phosphotransferases +
                                        is-aintramolecular transferase activity, transferring acyl groups +
                                        is-aintramolecular transferase activity, transferring amino groups +
                                        is-aintramolecular transferase activity, transferring hydroxy groups +
                                        is-aisobutyryl-CoA mutase activity
                                        is-aisomaltulose synthase activity
                                        is-amaltose alpha-D-glucosyltransferase activity
                                        is-amethylaspartate mutase activity
                                        is-amethylmalonyl-CoA mutase activity
                                        is-ao-hydroxylaminobenzoate mutase activity
                                        is-aoxidosqualene cyclase activity +
                                        is-apivalyl-CoA mutase activity
                                        is-apseudouridine synthase activity [GO:0009982] (13 genes, 16 annotations)
                                        is-asqualene-hopene cyclase activity
                                        is-aUDP-arabinopyranose mutase activity
                                        is-aUDP-galactopyranose mutase activity

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.08
The Jackson Laboratory