| GO term: | G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger |
| Synonym: | GPCR signaling pathway via cyclic nucleotide second messenger |
| Synonym: | G protein signaling, coupled to cyclic nucleotide second messenger |
| Synonym: | G-protein signaling, coupled to cyclic nucleotide second messenger |
| Synonym: | G protein signalling, coupled to cyclic nucleotide second messenger |
| Synonym: | G-protein signalling, coupled to cyclic nucleotide second messenger |
| GO id: | GO:0007187 |
| Definition: | The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand, where the pathway proceeds with activation or inhibition of a nucleotide cyclase activity and a subsequent change in the concentration of a cyclic nucleotide. |
| Number of paths to term: | 10 |
denotes an 'is-a' relationship
denotes a 'part-of' relationship
denotes a 'regulates' relationship
denotes a 'positively-regulates' relationship
denotes a 'negatively-regulates' relationship
biological_processbiological regulationregulation of biological processregulation of cellular processsignal transductioncell surface receptor signaling pathwayG-protein coupled receptor signaling pathwayadrenergic receptor signaling pathway +angiotensin-mediated signaling pathway +apelin receptor signaling pathwaybombesin receptor signaling pathwaycannabinoid signaling pathway +complement component C5a signaling pathwaydimeric G-protein coupled receptor signaling pathway +dopamine receptor signaling pathway +endothelin receptor signaling pathway +epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathwayfollicle-stimulating hormone signaling pathwayG-protein coupled acetylcholine receptor signaling pathway +G-protein coupled glutamate receptor signaling pathway +G-protein coupled purinergic receptor signaling pathway +G-protein coupled receptor signaling in absence of ligandG-protein coupled receptor signaling pathway involved in heart process +G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187] (108 genes, 176 annotations)adenylate cyclase-modulating G-protein coupled receptor signaling pathway +G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messengerG-protein coupled receptor signaling pathway, coupled to S1P second messengergamma-aminobutyric acid signaling pathwayheterotrimeric G-protein complex cycleluteinizing hormone signaling pathway +negative regulation of G-protein coupled receptor protein signaling pathway +neuropeptide signaling pathwayoctopamine or tyramine signaling pathway +opioid receptor signaling pathway +pheromone-dependent signal transduction involved in conjugation with cellular fusion +phospholipase C-activating G-protein coupled receptor signaling pathway +phospholipase C-inhibiting G-protein coupled receptor signaling pathwayphospholipase D-activating G-protein coupled receptor signaling pathwaypositive regulation of G-protein coupled receptor protein signaling pathway +protein kinase C-activating G-protein coupled receptor signaling pathwayregulation of G-protein coupled receptor protein signaling pathway +rhodopsin mediated signaling pathway +serotonin receptor signaling pathway +signal transduction involved in conjugation with mutual genetic exchangesomatostatin receptor signaling pathway +sphingosine-1-phosphate signaling pathway +tachykinin receptor signaling pathway +thrombin receptor signaling pathway +biological_processcellular processregulation of cellular processsignal transductioncell surface receptor signaling pathwayG-protein coupled receptor signaling pathwayadrenergic receptor signaling pathway +angiotensin-mediated signaling pathway +apelin receptor signaling pathwaybombesin receptor signaling pathwaycannabinoid signaling pathway +complement component C5a signaling pathwaydimeric G-protein coupled receptor signaling pathway +dopamine receptor signaling pathway +endothelin receptor signaling pathway +epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathwayfollicle-stimulating hormone signaling pathwayG-protein coupled acetylcholine receptor signaling pathway +G-protein coupled glutamate receptor signaling pathway +G-protein coupled purinergic receptor signaling pathway +G-protein coupled receptor signaling in absence of ligandG-protein coupled receptor signaling pathway involved in heart process +G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187] (108 genes, 176 annotations)adenylate cyclase-modulating G-protein coupled receptor signaling pathway +G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messengerG-protein coupled receptor signaling pathway, coupled to S1P second messengergamma-aminobutyric acid signaling pathwayheterotrimeric G-protein complex cycleluteinizing hormone signaling pathway +negative regulation of G-protein coupled receptor protein signaling pathway +neuropeptide signaling pathwayoctopamine or tyramine signaling pathway +opioid receptor signaling pathway +pheromone-dependent signal transduction involved in conjugation with cellular fusion +phospholipase C-activating G-protein coupled receptor signaling pathway +phospholipase C-inhibiting G-protein coupled receptor signaling pathwayphospholipase D-activating G-protein coupled receptor signaling pathwaypositive regulation of G-protein coupled receptor protein signaling pathway +protein kinase C-activating G-protein coupled receptor signaling pathwayregulation of G-protein coupled receptor protein signaling pathway +rhodopsin mediated signaling pathway +serotonin receptor signaling pathway +signal transduction involved in conjugation with mutual genetic exchangesomatostatin receptor signaling pathway +sphingosine-1-phosphate signaling pathway +tachykinin receptor signaling pathway +thrombin receptor signaling pathway +biological_processcellular processsingle-organism cellular processcell communicationsignal transductioncell surface receptor signaling pathwayG-protein coupled receptor signaling pathwayadrenergic receptor signaling pathway +angiotensin-mediated signaling pathway +apelin receptor signaling pathwaybombesin receptor signaling pathwaycannabinoid signaling pathway +complement component C5a signaling pathwaydimeric G-protein coupled receptor signaling pathway +dopamine receptor signaling pathway +endothelin receptor signaling pathway +epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathwayfollicle-stimulating hormone signaling pathwayG-protein coupled acetylcholine receptor signaling pathway +G-protein coupled glutamate receptor signaling pathway +G-protein coupled purinergic receptor signaling pathway +G-protein coupled receptor signaling in absence of ligandG-protein coupled receptor signaling pathway involved in heart process +G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187] (108 genes, 176 annotations)adenylate cyclase-modulating G-protein coupled receptor signaling pathway +G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messengerG-protein coupled receptor signaling pathway, coupled to S1P second messengergamma-aminobutyric acid signaling pathwayheterotrimeric G-protein complex cycleluteinizing hormone signaling pathway +negative regulation of G-protein coupled receptor protein signaling pathway +neuropeptide signaling pathwayoctopamine or tyramine signaling pathway +opioid receptor signaling pathway +pheromone-dependent signal transduction involved in conjugation with cellular fusion +phospholipase C-activating G-protein coupled receptor signaling pathway +phospholipase C-inhibiting G-protein coupled receptor signaling pathwayphospholipase D-activating G-protein coupled receptor signaling pathwaypositive regulation of G-protein coupled receptor protein signaling pathway +protein kinase C-activating G-protein coupled receptor signaling pathwayregulation of G-protein coupled receptor protein signaling pathway +rhodopsin mediated signaling pathway +serotonin receptor signaling pathway +signal transduction involved in conjugation with mutual genetic exchangesomatostatin receptor signaling pathway +sphingosine-1-phosphate signaling pathway +tachykinin receptor signaling pathway +thrombin receptor signaling pathway +biological_processcellular processsingle-organism cellular processcellular response to stimulussignal transductioncell surface receptor signaling pathwayG-protein coupled receptor signaling pathwayadrenergic receptor signaling pathway +angiotensin-mediated signaling pathway +apelin receptor signaling pathwaybombesin receptor signaling pathwaycannabinoid signaling pathway +complement component C5a signaling pathwaydimeric G-protein coupled receptor signaling pathway +dopamine receptor signaling pathway +endothelin receptor signaling pathway +epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathwayfollicle-stimulating hormone signaling pathwayG-protein coupled acetylcholine receptor signaling pathway +G-protein coupled glutamate receptor signaling pathway +G-protein coupled purinergic receptor signaling pathway +G-protein coupled receptor signaling in absence of ligandG-protein coupled receptor signaling pathway involved in heart process +G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187] (108 genes, 176 annotations)adenylate cyclase-modulating G-protein coupled receptor signaling pathway +G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messengerG-protein coupled receptor signaling pathway, coupled to S1P second messengergamma-aminobutyric acid signaling pathwayheterotrimeric G-protein complex cycleluteinizing hormone signaling pathway +negative regulation of G-protein coupled receptor protein signaling pathway +neuropeptide signaling pathwayoctopamine or tyramine signaling pathway +opioid receptor signaling pathway +pheromone-dependent signal transduction involved in conjugation with cellular fusion +phospholipase C-activating G-protein coupled receptor signaling pathway +phospholipase C-inhibiting G-protein coupled receptor signaling pathwayphospholipase D-activating G-protein coupled receptor signaling pathwaypositive regulation of G-protein coupled receptor protein signaling pathway +protein kinase C-activating G-protein coupled receptor signaling pathwayregulation of G-protein coupled receptor protein signaling pathway +rhodopsin mediated signaling pathway +serotonin receptor signaling pathway +signal transduction involved in conjugation with mutual genetic exchangesomatostatin receptor signaling pathway +sphingosine-1-phosphate signaling pathway +tachykinin receptor signaling pathway +thrombin receptor signaling pathway +biological_processregulation of biological processregulation of cellular processsignal transductioncell surface receptor signaling pathwayG-protein coupled receptor signaling pathwayadrenergic receptor signaling pathway +angiotensin-mediated signaling pathway +apelin receptor signaling pathwaybombesin receptor signaling pathwaycannabinoid signaling pathway +complement component C5a signaling pathwaydimeric G-protein coupled receptor signaling pathway +dopamine receptor signaling pathway +endothelin receptor signaling pathway +epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathwayfollicle-stimulating hormone signaling pathwayG-protein coupled acetylcholine receptor signaling pathway +G-protein coupled glutamate receptor signaling pathway +G-protein coupled purinergic receptor signaling pathway +G-protein coupled receptor signaling in absence of ligandG-protein coupled receptor signaling pathway involved in heart process +G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187] (108 genes, 176 annotations)adenylate cyclase-modulating G-protein coupled receptor signaling pathway +G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messengerG-protein coupled receptor signaling pathway, coupled to S1P second messengergamma-aminobutyric acid signaling pathwayheterotrimeric G-protein complex cycleluteinizing hormone signaling pathway +negative regulation of G-protein coupled receptor protein signaling pathway +neuropeptide signaling pathwayoctopamine or tyramine signaling pathway +opioid receptor signaling pathway +pheromone-dependent signal transduction involved in conjugation with cellular fusion +phospholipase C-activating G-protein coupled receptor signaling pathway +phospholipase C-inhibiting G-protein coupled receptor signaling pathwayphospholipase D-activating G-protein coupled receptor signaling pathwaypositive regulation of G-protein coupled receptor protein signaling pathway +protein kinase C-activating G-protein coupled receptor signaling pathwayregulation of G-protein coupled receptor protein signaling pathway +rhodopsin mediated signaling pathway +serotonin receptor signaling pathway +signal transduction involved in conjugation with mutual genetic exchangesomatostatin receptor signaling pathway +sphingosine-1-phosphate signaling pathway +tachykinin receptor signaling pathway +thrombin receptor signaling pathway +biological_processresponse to stimuluscellular response to stimulussignal transductioncell surface receptor signaling pathwayG-protein coupled receptor signaling pathwayadrenergic receptor signaling pathway +angiotensin-mediated signaling pathway +apelin receptor signaling pathwaybombesin receptor signaling pathwaycannabinoid signaling pathway +complement component C5a signaling pathwaydimeric G-protein coupled receptor signaling pathway +dopamine receptor signaling pathway +endothelin receptor signaling pathway +epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathwayfollicle-stimulating hormone signaling pathwayG-protein coupled acetylcholine receptor signaling pathway +G-protein coupled glutamate receptor signaling pathway +G-protein coupled purinergic receptor signaling pathway +G-protein coupled receptor signaling in absence of ligandG-protein coupled receptor signaling pathway involved in heart process +G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187] (108 genes, 176 annotations)adenylate cyclase-modulating G-protein coupled receptor signaling pathway +G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messengerG-protein coupled receptor signaling pathway, coupled to S1P second messengergamma-aminobutyric acid signaling pathwayheterotrimeric G-protein complex cycleluteinizing hormone signaling pathway +negative regulation of G-protein coupled receptor protein signaling pathway +neuropeptide signaling pathwayoctopamine or tyramine signaling pathway +opioid receptor signaling pathway +pheromone-dependent signal transduction involved in conjugation with cellular fusion +phospholipase C-activating G-protein coupled receptor signaling pathway +phospholipase C-inhibiting G-protein coupled receptor signaling pathwayphospholipase D-activating G-protein coupled receptor signaling pathwaypositive regulation of G-protein coupled receptor protein signaling pathway +protein kinase C-activating G-protein coupled receptor signaling pathwayregulation of G-protein coupled receptor protein signaling pathway +rhodopsin mediated signaling pathway +serotonin receptor signaling pathway +signal transduction involved in conjugation with mutual genetic exchangesomatostatin receptor signaling pathway +sphingosine-1-phosphate signaling pathway +tachykinin receptor signaling pathway +thrombin receptor signaling pathway +biological_processsignalingsingle organism signalingsignal transductioncell surface receptor signaling pathwayG-protein coupled receptor signaling pathwayadrenergic receptor signaling pathway +angiotensin-mediated signaling pathway +apelin receptor signaling pathwaybombesin receptor signaling pathwaycannabinoid signaling pathway +complement component C5a signaling pathwaydimeric G-protein coupled receptor signaling pathway +dopamine receptor signaling pathway +endothelin receptor signaling pathway +epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathwayfollicle-stimulating hormone signaling pathwayG-protein coupled acetylcholine receptor signaling pathway +G-protein coupled glutamate receptor signaling pathway +G-protein coupled purinergic receptor signaling pathway +G-protein coupled receptor signaling in absence of ligandG-protein coupled receptor signaling pathway involved in heart process +G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187] (108 genes, 176 annotations)adenylate cyclase-modulating G-protein coupled receptor signaling pathway +G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messengerG-protein coupled receptor signaling pathway, coupled to S1P second messengergamma-aminobutyric acid signaling pathwayheterotrimeric G-protein complex cycleluteinizing hormone signaling pathway +negative regulation of G-protein coupled receptor protein signaling pathway +neuropeptide signaling pathwayoctopamine or tyramine signaling pathway +opioid receptor signaling pathway +pheromone-dependent signal transduction involved in conjugation with cellular fusion +phospholipase C-activating G-protein coupled receptor signaling pathway +phospholipase C-inhibiting G-protein coupled receptor signaling pathwayphospholipase D-activating G-protein coupled receptor signaling pathwaypositive regulation of G-protein coupled receptor protein signaling pathway +protein kinase C-activating G-protein coupled receptor signaling pathwayregulation of G-protein coupled receptor protein signaling pathway +rhodopsin mediated signaling pathway +serotonin receptor signaling pathway +signal transduction involved in conjugation with mutual genetic exchangesomatostatin receptor signaling pathway +sphingosine-1-phosphate signaling pathway +tachykinin receptor signaling pathway +thrombin receptor signaling pathway +biological_processsingle-organism processsingle organism signalingsignal transductioncell surface receptor signaling pathwayG-protein coupled receptor signaling pathwayadrenergic receptor signaling pathway +angiotensin-mediated signaling pathway +apelin receptor signaling pathwaybombesin receptor signaling pathwaycannabinoid signaling pathway +complement component C5a signaling pathwaydimeric G-protein coupled receptor signaling pathway +dopamine receptor signaling pathway +endothelin receptor signaling pathway +epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathwayfollicle-stimulating hormone signaling pathwayG-protein coupled acetylcholine receptor signaling pathway +G-protein coupled glutamate receptor signaling pathway +G-protein coupled purinergic receptor signaling pathway +G-protein coupled receptor signaling in absence of ligandG-protein coupled receptor signaling pathway involved in heart process +G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187] (108 genes, 176 annotations)adenylate cyclase-modulating G-protein coupled receptor signaling pathway +G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messengerG-protein coupled receptor signaling pathway, coupled to S1P second messengergamma-aminobutyric acid signaling pathwayheterotrimeric G-protein complex cycleluteinizing hormone signaling pathway +negative regulation of G-protein coupled receptor protein signaling pathway +neuropeptide signaling pathwayoctopamine or tyramine signaling pathway +opioid receptor signaling pathway +pheromone-dependent signal transduction involved in conjugation with cellular fusion +phospholipase C-activating G-protein coupled receptor signaling pathway +phospholipase C-inhibiting G-protein coupled receptor signaling pathwayphospholipase D-activating G-protein coupled receptor signaling pathwaypositive regulation of G-protein coupled receptor protein signaling pathway +protein kinase C-activating G-protein coupled receptor signaling pathwayregulation of G-protein coupled receptor protein signaling pathway +rhodopsin mediated signaling pathway +serotonin receptor signaling pathway +signal transduction involved in conjugation with mutual genetic exchangesomatostatin receptor signaling pathway +sphingosine-1-phosphate signaling pathway +tachykinin receptor signaling pathway +thrombin receptor signaling pathway +biological_processsingle-organism processsingle-organism cellular processcell communicationsignal transductioncell surface receptor signaling pathwayG-protein coupled receptor signaling pathwayadrenergic receptor signaling pathway +angiotensin-mediated signaling pathway +apelin receptor signaling pathwaybombesin receptor signaling pathwaycannabinoid signaling pathway +complement component C5a signaling pathwaydimeric G-protein coupled receptor signaling pathway +dopamine receptor signaling pathway +endothelin receptor signaling pathway +epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathwayfollicle-stimulating hormone signaling pathwayG-protein coupled acetylcholine receptor signaling pathway +G-protein coupled glutamate receptor signaling pathway +G-protein coupled purinergic receptor signaling pathway +G-protein coupled receptor signaling in absence of ligandG-protein coupled receptor signaling pathway involved in heart process +G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187] (108 genes, 176 annotations)adenylate cyclase-modulating G-protein coupled receptor signaling pathway +G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messengerG-protein coupled receptor signaling pathway, coupled to S1P second messengergamma-aminobutyric acid signaling pathwayheterotrimeric G-protein complex cycleluteinizing hormone signaling pathway +negative regulation of G-protein coupled receptor protein signaling pathway +neuropeptide signaling pathwayoctopamine or tyramine signaling pathway +opioid receptor signaling pathway +pheromone-dependent signal transduction involved in conjugation with cellular fusion +phospholipase C-activating G-protein coupled receptor signaling pathway +phospholipase C-inhibiting G-protein coupled receptor signaling pathwayphospholipase D-activating G-protein coupled receptor signaling pathwaypositive regulation of G-protein coupled receptor protein signaling pathway +protein kinase C-activating G-protein coupled receptor signaling pathwayregulation of G-protein coupled receptor protein signaling pathway +rhodopsin mediated signaling pathway +serotonin receptor signaling pathway +signal transduction involved in conjugation with mutual genetic exchangesomatostatin receptor signaling pathway +sphingosine-1-phosphate signaling pathway +tachykinin receptor signaling pathway +thrombin receptor signaling pathway +biological_processsingle-organism processsingle-organism cellular processcellular response to stimulussignal transductioncell surface receptor signaling pathwayG-protein coupled receptor signaling pathwayadrenergic receptor signaling pathway +angiotensin-mediated signaling pathway +apelin receptor signaling pathwaybombesin receptor signaling pathwaycannabinoid signaling pathway +complement component C5a signaling pathwaydimeric G-protein coupled receptor signaling pathway +dopamine receptor signaling pathway +endothelin receptor signaling pathway +epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathwayfollicle-stimulating hormone signaling pathwayG-protein coupled acetylcholine receptor signaling pathway +G-protein coupled glutamate receptor signaling pathway +G-protein coupled purinergic receptor signaling pathway +G-protein coupled receptor signaling in absence of ligandG-protein coupled receptor signaling pathway involved in heart process +G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187] (108 genes, 176 annotations)adenylate cyclase-modulating G-protein coupled receptor signaling pathway +G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messengerG-protein coupled receptor signaling pathway, coupled to S1P second messengergamma-aminobutyric acid signaling pathwayheterotrimeric G-protein complex cycleluteinizing hormone signaling pathway +negative regulation of G-protein coupled receptor protein signaling pathway +neuropeptide signaling pathwayoctopamine or tyramine signaling pathway +opioid receptor signaling pathway +pheromone-dependent signal transduction involved in conjugation with cellular fusion +phospholipase C-activating G-protein coupled receptor signaling pathway +phospholipase C-inhibiting G-protein coupled receptor signaling pathwayphospholipase D-activating G-protein coupled receptor signaling pathwaypositive regulation of G-protein coupled receptor protein signaling pathway +protein kinase C-activating G-protein coupled receptor signaling pathwayregulation of G-protein coupled receptor protein signaling pathway +rhodopsin mediated signaling pathway +serotonin receptor signaling pathway +signal transduction involved in conjugation with mutual genetic exchangesomatostatin receptor signaling pathway +sphingosine-1-phosphate signaling pathway +tachykinin receptor signaling pathway +thrombin receptor signaling pathway +Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc |
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last database update 05/08/2013 MGI 5.13 |
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