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Term Detail
GO term:response to stress
Synonym: response to abiotic stress
Synonym: response to biotic stress
GO id:GO:0006950
Definition:Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
CommentsNote that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
Number of paths to term: 1

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship

                is-aresponse to stimulus
                        is-acellular response to stimulus +
                        is-adetection of stimulus +
                        is-aimmune response +
                        is-amuscle adaptation +
                        negatively-regulatesnegative regulation of response to stimulus +
                        positively-regulatespositive regulation of response to stimulus +
                        is-aprotein activation cascade +
                        regulatesregulation of response to stimulus +
                        is-aresponse to abiotic stimulus +
                        is-aresponse to activity +
                        is-aresponse to biotic stimulus +
                        is-aresponse to chemical +
                        is-aresponse to endogenous stimulus +
                        is-aresponse to estrogen +
                        is-aresponse to external stimulus +
                        is-aresponse to inactivity +
                        is-aresponse to redox state +
                        is-aresponse to stimulus involved in regulation of muscle adaptation +
                        is-aresponse to stress [GO:0006950] (3273 genes, 7920 annotations)
                                is-acellular response to stress +
                                is-adefense response +
                                is-amulticellular organismal response to stress +
                                is-amuscle hypertrophy in response to stress +
                                is-aphage shock
                                regulatesregulation of response to stress +
                                is-aresponse to anoxia +
                                is-aresponse to caloric restriction +
                                is-aresponse to cold +
                                is-aresponse to flooding
                                is-aresponse to fluid shear stress +
                                is-aresponse to heat +
                                is-aresponse to herbicide
                                is-aresponse to high population density
                                is-aresponse to hydrostatic pressure +
                                is-aresponse to hyperoxia +
                                is-aresponse to hypoxia +
                                is-aresponse to immobilization stress +
                                is-aresponse to ischemia
                                is-aresponse to isolation stress +
                                is-aresponse to nitrosative stress +
                                is-aresponse to osmotic stress +
                                is-aresponse to oxidative stress +
                                is-aresponse to psychosocial stress
                                is-aresponse to starvation +
                                is-aresponse to sterol depletion +
                                is-aresponse to topologically incorrect protein +
                                is-aresponse to water deprivation +
                                is-aresponse to wounding +
                                is-astress response to acid chemical +
                                is-astress response to metal ion +

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.08
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