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Gene Ontology Browser
Term Detail
GO term:misfolded or incompletely synthesized protein catabolic process
Synonym: degradation of misfolded or incompletely synthesized proteins
Synonym: misfolded or incompletely synthesized protein breakdown
Synonym: misfolded or incompletely synthesized protein catabolism
Synonym: misfolded or incompletely synthesized protein degradation
GO id:GO:0006515
Definition:The chemical reactions and pathways resulting in the breakdown of misfolded or attenuated proteins.
Number of paths to term: 22

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-acellular metabolic process
                                is-acellular catabolic process
                                        is-acellular macromolecule catabolic process
                                                is-acellular protein catabolic process
                                                        part-ofproteolysis involved in cellular protein catabolic process
                                                                is-aacrosome matrix dispersal
                                                                is-amannoprotein catabolic process
                                                                is-amisfolded or incompletely synthesized protein catabolic process [GO:0006515] (11 genes, 12 annotations)
                                                                        is-acytoplasm-associated proteasomal ubiquitin-dependent protein catabolic process
                                                                        is-aER-associated misfolded protein catabolic process
                                                                        is-anucleus-associated proteasomal ubiquitin-dependent protein catabolic process +
                                                                is-amodification-dependent protein catabolic process +
                                                                is-aproteasomal protein catabolic process +
                                                                is-aproteolysis associated with antigen processing and presentation +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-acellular metabolic process
                                is-acellular macromolecule metabolic process
                                        is-acellular macromolecule catabolic process
                                                is-acellular protein catabolic process
                                                        part-ofproteolysis involved in cellular protein catabolic process
                                                                is-aacrosome matrix dispersal
                                                                is-amannoprotein catabolic process
                                                                is-amisfolded or incompletely synthesized protein catabolic process [GO:0006515] (11 genes, 12 annotations)
                                                                        is-acytoplasm-associated proteasomal ubiquitin-dependent protein catabolic process
                                                                        is-aER-associated misfolded protein catabolic process
                                                                        is-anucleus-associated proteasomal ubiquitin-dependent protein catabolic process +
                                                                is-amodification-dependent protein catabolic process +
                                                                is-aproteasomal protein catabolic process +
                                                                is-aproteolysis associated with antigen processing and presentation +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-acellular metabolic process
                                is-acellular macromolecule metabolic process
                                        is-acellular protein metabolic process
                                                is-acellular protein catabolic process
                                                        part-ofproteolysis involved in cellular protein catabolic process
                                                                is-aacrosome matrix dispersal
                                                                is-amannoprotein catabolic process
                                                                is-amisfolded or incompletely synthesized protein catabolic process [GO:0006515] (11 genes, 12 annotations)
                                                                        is-acytoplasm-associated proteasomal ubiquitin-dependent protein catabolic process
                                                                        is-aER-associated misfolded protein catabolic process
                                                                        is-anucleus-associated proteasomal ubiquitin-dependent protein catabolic process +
                                                                is-amodification-dependent protein catabolic process +
                                                                is-aproteasomal protein catabolic process +
                                                                is-aproteolysis associated with antigen processing and presentation +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-acatabolic process
                                is-acellular catabolic process
                                        is-acellular macromolecule catabolic process
                                                is-acellular protein catabolic process
                                                        part-ofproteolysis involved in cellular protein catabolic process
                                                                is-aacrosome matrix dispersal
                                                                is-amannoprotein catabolic process
                                                                is-amisfolded or incompletely synthesized protein catabolic process [GO:0006515] (11 genes, 12 annotations)
                                                                        is-acytoplasm-associated proteasomal ubiquitin-dependent protein catabolic process
                                                                        is-aER-associated misfolded protein catabolic process
                                                                        is-anucleus-associated proteasomal ubiquitin-dependent protein catabolic process +
                                                                is-amodification-dependent protein catabolic process +
                                                                is-aproteasomal protein catabolic process +
                                                                is-aproteolysis associated with antigen processing and presentation +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-acatabolic process
                                is-aorganic substance catabolic process
                                        is-amacromolecule catabolic process
                                                is-acellular macromolecule catabolic process
                                                        is-acellular protein catabolic process
                                                                part-ofproteolysis involved in cellular protein catabolic process
                                                                        is-aacrosome matrix dispersal
                                                                        is-amannoprotein catabolic process
                                                                        is-amisfolded or incompletely synthesized protein catabolic process [GO:0006515] (11 genes, 12 annotations)
                                                                                is-acytoplasm-associated proteasomal ubiquitin-dependent protein catabolic process
                                                                                is-aER-associated misfolded protein catabolic process
                                                                                is-anucleus-associated proteasomal ubiquitin-dependent protein catabolic process +
                                                                        is-amodification-dependent protein catabolic process +
                                                                        is-aproteasomal protein catabolic process +
                                                                        is-aproteolysis associated with antigen processing and presentation +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-acatabolic process
                                is-aorganic substance catabolic process
                                        is-amacromolecule catabolic process
                                                is-aprotein catabolic process
                                                        is-acellular protein catabolic process
                                                                part-ofproteolysis involved in cellular protein catabolic process
                                                                        is-aacrosome matrix dispersal
                                                                        is-amannoprotein catabolic process
                                                                        is-amisfolded or incompletely synthesized protein catabolic process [GO:0006515] (11 genes, 12 annotations)
                                                                                is-acytoplasm-associated proteasomal ubiquitin-dependent protein catabolic process
                                                                                is-aER-associated misfolded protein catabolic process
                                                                                is-anucleus-associated proteasomal ubiquitin-dependent protein catabolic process +
                                                                        is-amodification-dependent protein catabolic process +
                                                                        is-aproteasomal protein catabolic process +
                                                                        is-aproteolysis associated with antigen processing and presentation +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-acellular metabolic process
                                is-acellular catabolic process
                                        is-acellular macromolecule catabolic process
                                                is-acellular protein catabolic process
                                                        part-ofproteolysis involved in cellular protein catabolic process
                                                                is-aacrosome matrix dispersal
                                                                is-amannoprotein catabolic process
                                                                is-amisfolded or incompletely synthesized protein catabolic process [GO:0006515] (11 genes, 12 annotations)
                                                                        is-acytoplasm-associated proteasomal ubiquitin-dependent protein catabolic process
                                                                        is-aER-associated misfolded protein catabolic process
                                                                        is-anucleus-associated proteasomal ubiquitin-dependent protein catabolic process +
                                                                is-amodification-dependent protein catabolic process +
                                                                is-aproteasomal protein catabolic process +
                                                                is-aproteolysis associated with antigen processing and presentation +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-acellular metabolic process
                                is-acellular macromolecule metabolic process
                                        is-acellular macromolecule catabolic process
                                                is-acellular protein catabolic process
                                                        part-ofproteolysis involved in cellular protein catabolic process
                                                                is-aacrosome matrix dispersal
                                                                is-amannoprotein catabolic process
                                                                is-amisfolded or incompletely synthesized protein catabolic process [GO:0006515] (11 genes, 12 annotations)
                                                                        is-acytoplasm-associated proteasomal ubiquitin-dependent protein catabolic process
                                                                        is-aER-associated misfolded protein catabolic process
                                                                        is-anucleus-associated proteasomal ubiquitin-dependent protein catabolic process +
                                                                is-amodification-dependent protein catabolic process +
                                                                is-aproteasomal protein catabolic process +
                                                                is-aproteolysis associated with antigen processing and presentation +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-acellular metabolic process
                                is-acellular macromolecule metabolic process
                                        is-acellular protein metabolic process
                                                is-acellular protein catabolic process
                                                        part-ofproteolysis involved in cellular protein catabolic process
                                                                is-aacrosome matrix dispersal
                                                                is-amannoprotein catabolic process
                                                                is-amisfolded or incompletely synthesized protein catabolic process [GO:0006515] (11 genes, 12 annotations)
                                                                        is-acytoplasm-associated proteasomal ubiquitin-dependent protein catabolic process
                                                                        is-aER-associated misfolded protein catabolic process
                                                                        is-anucleus-associated proteasomal ubiquitin-dependent protein catabolic process +
                                                                is-amodification-dependent protein catabolic process +
                                                                is-aproteasomal protein catabolic process +
                                                                is-aproteolysis associated with antigen processing and presentation +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aorganic substance metabolic process
                                is-amacromolecule metabolic process
                                        is-acellular macromolecule metabolic process
                                                is-acellular macromolecule catabolic process
                                                        is-acellular protein catabolic process
                                                                part-ofproteolysis involved in cellular protein catabolic process
                                                                        is-aacrosome matrix dispersal
                                                                        is-amannoprotein catabolic process
                                                                        is-amisfolded or incompletely synthesized protein catabolic process [GO:0006515] (11 genes, 12 annotations)
                                                                                is-acytoplasm-associated proteasomal ubiquitin-dependent protein catabolic process
                                                                                is-aER-associated misfolded protein catabolic process
                                                                                is-anucleus-associated proteasomal ubiquitin-dependent protein catabolic process +
                                                                        is-amodification-dependent protein catabolic process +
                                                                        is-aproteasomal protein catabolic process +
                                                                        is-aproteolysis associated with antigen processing and presentation +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aorganic substance metabolic process
                                is-amacromolecule metabolic process
                                        is-acellular macromolecule metabolic process
                                                is-acellular protein metabolic process
                                                        is-acellular protein catabolic process
                                                                part-ofproteolysis involved in cellular protein catabolic process
                                                                        is-aacrosome matrix dispersal
                                                                        is-amannoprotein catabolic process
                                                                        is-amisfolded or incompletely synthesized protein catabolic process [GO:0006515] (11 genes, 12 annotations)
                                                                                is-acytoplasm-associated proteasomal ubiquitin-dependent protein catabolic process
                                                                                is-aER-associated misfolded protein catabolic process
                                                                                is-anucleus-associated proteasomal ubiquitin-dependent protein catabolic process +
                                                                        is-amodification-dependent protein catabolic process +
                                                                        is-aproteasomal protein catabolic process +
                                                                        is-aproteolysis associated with antigen processing and presentation +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aorganic substance metabolic process
                                is-amacromolecule metabolic process
                                        is-agene expression
                                                part-ofprotein maturation
                                                        is-aprotein processing
                                                                is-aproteolysis
                                                                        is-aproteolysis involved in cellular protein catabolic process
                                                                                is-aacrosome matrix dispersal
                                                                                is-amannoprotein catabolic process
                                                                                is-amisfolded or incompletely synthesized protein catabolic process [GO:0006515] (11 genes, 12 annotations)
                                                                                        is-acytoplasm-associated proteasomal ubiquitin-dependent protein catabolic process
                                                                                        is-aER-associated misfolded protein catabolic process
                                                                                        is-anucleus-associated proteasomal ubiquitin-dependent protein catabolic process +
                                                                                is-amodification-dependent protein catabolic process +
                                                                                is-aproteasomal protein catabolic process +
                                                                                is-aproteolysis associated with antigen processing and presentation +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aorganic substance metabolic process
                                is-amacromolecule metabolic process
                                        is-amacromolecule catabolic process
                                                is-acellular macromolecule catabolic process
                                                        is-acellular protein catabolic process
                                                                part-ofproteolysis involved in cellular protein catabolic process
                                                                        is-aacrosome matrix dispersal
                                                                        is-amannoprotein catabolic process
                                                                        is-amisfolded or incompletely synthesized protein catabolic process [GO:0006515] (11 genes, 12 annotations)
                                                                                is-acytoplasm-associated proteasomal ubiquitin-dependent protein catabolic process
                                                                                is-aER-associated misfolded protein catabolic process
                                                                                is-anucleus-associated proteasomal ubiquitin-dependent protein catabolic process +
                                                                        is-amodification-dependent protein catabolic process +
                                                                        is-aproteasomal protein catabolic process +
                                                                        is-aproteolysis associated with antigen processing and presentation +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aorganic substance metabolic process
                                is-amacromolecule metabolic process
                                        is-amacromolecule catabolic process
                                                is-aprotein catabolic process
                                                        is-acellular protein catabolic process
                                                                part-ofproteolysis involved in cellular protein catabolic process
                                                                        is-aacrosome matrix dispersal
                                                                        is-amannoprotein catabolic process
                                                                        is-amisfolded or incompletely synthesized protein catabolic process [GO:0006515] (11 genes, 12 annotations)
                                                                                is-acytoplasm-associated proteasomal ubiquitin-dependent protein catabolic process
                                                                                is-aER-associated misfolded protein catabolic process
                                                                                is-anucleus-associated proteasomal ubiquitin-dependent protein catabolic process +
                                                                        is-amodification-dependent protein catabolic process +
                                                                        is-aproteasomal protein catabolic process +
                                                                        is-aproteolysis associated with antigen processing and presentation +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aorganic substance metabolic process
                                is-amacromolecule metabolic process
                                        is-aprotein metabolic process
                                                is-acellular protein metabolic process
                                                        is-acellular protein catabolic process
                                                                part-ofproteolysis involved in cellular protein catabolic process
                                                                        is-aacrosome matrix dispersal
                                                                        is-amannoprotein catabolic process
                                                                        is-amisfolded or incompletely synthesized protein catabolic process [GO:0006515] (11 genes, 12 annotations)
                                                                                is-acytoplasm-associated proteasomal ubiquitin-dependent protein catabolic process
                                                                                is-aER-associated misfolded protein catabolic process
                                                                                is-anucleus-associated proteasomal ubiquitin-dependent protein catabolic process +
                                                                        is-amodification-dependent protein catabolic process +
                                                                        is-aproteasomal protein catabolic process +
                                                                        is-aproteolysis associated with antigen processing and presentation +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aorganic substance metabolic process
                                is-amacromolecule metabolic process
                                        is-aprotein metabolic process
                                                is-aprotein catabolic process
                                                        is-acellular protein catabolic process
                                                                part-ofproteolysis involved in cellular protein catabolic process
                                                                        is-aacrosome matrix dispersal
                                                                        is-amannoprotein catabolic process
                                                                        is-amisfolded or incompletely synthesized protein catabolic process [GO:0006515] (11 genes, 12 annotations)
                                                                                is-acytoplasm-associated proteasomal ubiquitin-dependent protein catabolic process
                                                                                is-aER-associated misfolded protein catabolic process
                                                                                is-anucleus-associated proteasomal ubiquitin-dependent protein catabolic process +
                                                                        is-amodification-dependent protein catabolic process +
                                                                        is-aproteasomal protein catabolic process +
                                                                        is-aproteolysis associated with antigen processing and presentation +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aorganic substance metabolic process
                                is-amacromolecule metabolic process
                                        is-aprotein metabolic process
                                                is-aprotein maturation
                                                        is-aprotein processing
                                                                is-aproteolysis
                                                                        is-aproteolysis involved in cellular protein catabolic process
                                                                                is-aacrosome matrix dispersal
                                                                                is-amannoprotein catabolic process
                                                                                is-amisfolded or incompletely synthesized protein catabolic process [GO:0006515] (11 genes, 12 annotations)
                                                                                        is-acytoplasm-associated proteasomal ubiquitin-dependent protein catabolic process
                                                                                        is-aER-associated misfolded protein catabolic process
                                                                                        is-anucleus-associated proteasomal ubiquitin-dependent protein catabolic process +
                                                                                is-amodification-dependent protein catabolic process +
                                                                                is-aproteasomal protein catabolic process +
                                                                                is-aproteolysis associated with antigen processing and presentation +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aorganic substance metabolic process
                                is-aorganic substance catabolic process
                                        is-amacromolecule catabolic process
                                                is-acellular macromolecule catabolic process
                                                        is-acellular protein catabolic process
                                                                part-ofproteolysis involved in cellular protein catabolic process
                                                                        is-aacrosome matrix dispersal
                                                                        is-amannoprotein catabolic process
                                                                        is-amisfolded or incompletely synthesized protein catabolic process [GO:0006515] (11 genes, 12 annotations)
                                                                                is-acytoplasm-associated proteasomal ubiquitin-dependent protein catabolic process
                                                                                is-aER-associated misfolded protein catabolic process
                                                                                is-anucleus-associated proteasomal ubiquitin-dependent protein catabolic process +
                                                                        is-amodification-dependent protein catabolic process +
                                                                        is-aproteasomal protein catabolic process +
                                                                        is-aproteolysis associated with antigen processing and presentation +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aorganic substance metabolic process
                                is-aorganic substance catabolic process
                                        is-amacromolecule catabolic process
                                                is-aprotein catabolic process
                                                        is-acellular protein catabolic process
                                                                part-ofproteolysis involved in cellular protein catabolic process
                                                                        is-aacrosome matrix dispersal
                                                                        is-amannoprotein catabolic process
                                                                        is-amisfolded or incompletely synthesized protein catabolic process [GO:0006515] (11 genes, 12 annotations)
                                                                                is-acytoplasm-associated proteasomal ubiquitin-dependent protein catabolic process
                                                                                is-aER-associated misfolded protein catabolic process
                                                                                is-anucleus-associated proteasomal ubiquitin-dependent protein catabolic process +
                                                                        is-amodification-dependent protein catabolic process +
                                                                        is-aproteasomal protein catabolic process +
                                                                        is-aproteolysis associated with antigen processing and presentation +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aprimary metabolic process
                                is-aprotein metabolic process
                                        is-acellular protein metabolic process
                                                is-acellular protein catabolic process
                                                        part-ofproteolysis involved in cellular protein catabolic process
                                                                is-aacrosome matrix dispersal
                                                                is-amannoprotein catabolic process
                                                                is-amisfolded or incompletely synthesized protein catabolic process [GO:0006515] (11 genes, 12 annotations)
                                                                        is-acytoplasm-associated proteasomal ubiquitin-dependent protein catabolic process
                                                                        is-aER-associated misfolded protein catabolic process
                                                                        is-anucleus-associated proteasomal ubiquitin-dependent protein catabolic process +
                                                                is-amodification-dependent protein catabolic process +
                                                                is-aproteasomal protein catabolic process +
                                                                is-aproteolysis associated with antigen processing and presentation +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aprimary metabolic process
                                is-aprotein metabolic process
                                        is-aprotein catabolic process
                                                is-acellular protein catabolic process
                                                        part-ofproteolysis involved in cellular protein catabolic process
                                                                is-aacrosome matrix dispersal
                                                                is-amannoprotein catabolic process
                                                                is-amisfolded or incompletely synthesized protein catabolic process [GO:0006515] (11 genes, 12 annotations)
                                                                        is-acytoplasm-associated proteasomal ubiquitin-dependent protein catabolic process
                                                                        is-aER-associated misfolded protein catabolic process
                                                                        is-anucleus-associated proteasomal ubiquitin-dependent protein catabolic process +
                                                                is-amodification-dependent protein catabolic process +
                                                                is-aproteasomal protein catabolic process +
                                                                is-aproteolysis associated with antigen processing and presentation +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aprimary metabolic process
                                is-aprotein metabolic process
                                        is-aprotein maturation
                                                is-aprotein processing
                                                        is-aproteolysis
                                                                is-aproteolysis involved in cellular protein catabolic process
                                                                        is-aacrosome matrix dispersal
                                                                        is-amannoprotein catabolic process
                                                                        is-amisfolded or incompletely synthesized protein catabolic process [GO:0006515] (11 genes, 12 annotations)
                                                                                is-acytoplasm-associated proteasomal ubiquitin-dependent protein catabolic process
                                                                                is-aER-associated misfolded protein catabolic process
                                                                                is-anucleus-associated proteasomal ubiquitin-dependent protein catabolic process +
                                                                        is-amodification-dependent protein catabolic process +
                                                                        is-aproteasomal protein catabolic process +
                                                                        is-aproteolysis associated with antigen processing and presentation +


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory