| GO term: | integral to plasma membrane |
| GO id: | GO:0005887 |
| Definition: | Penetrating at least one phospholipid bilayer of a plasma membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer. |
| Number of paths to term: | 13 |
denotes an 'is-a' relationship
denotes a 'part-of' relationship
denotes a 'regulates' relationship
denotes a 'positively-regulates' relationship
denotes a 'negatively-regulates' relationship
cellular_componentcellcell partcell peripheryplasma membraneplasma membrane partintrinsic to plasma membraneanchored to plasma membrane +integral to plasma membrane [GO:0005887] (692 genes, 793 annotations)acetylcholine-gated channel complexactivin receptor complexalphav-beta5 integrin-vitronectin complexATP-sensitive potassium channel complexBMP receptor complexCD40 receptor complexciliary neurotrophic factor receptor complexglycine-gated chloride channel complexgranulocyte macrophage colony-stimulating factor receptor complexhigh molecular weight kininogen receptor complexhistamine-gated chloride channel complexhydrogen:potassium-exchanging ATPase complexinsulin receptor complexintegral to external side of plasma membraneintegral to muscle cell projection membraneintegrin complex +interleukin-1 receptor complexinterleukin-12 receptor complexinterleukin-13 receptor complexinterleukin-18 receptor complexinterleukin-2 receptor complexinterleukin-20 receptor complexinterleukin-23 receptor complexinterleukin-28 receptor complexinterleukin-3 receptor complexinterleukin-4 receptor complexinterleukin-5 receptor complexinterleukin-6 receptor complexinterleukin-9 receptor complexionotropic glutamate receptor complex +membrane attack complexNADPH oxidase complexoncostatin-M receptor complexplasma membrane proton-transporting V-type ATPase, V0 domainplasma membrane proton-transporting V-type ATPase, V1 domainpre-T cell receptor complexSC5b-7 complexsodium:potassium-exchanging ATPase complexsucrase-isomaltase complextransforming growth factor beta receptor homodimeric complex +voltage-gated potassium channel complex +voltage-gated sodium channel complexintrinsic to external side of plasma membrane +intrinsic to internal side of plasma membranecellular_componentcellcell partplasma membraneplasma membrane partintrinsic to plasma membraneanchored to plasma membrane +integral to plasma membrane [GO:0005887] (692 genes, 793 annotations)acetylcholine-gated channel complexactivin receptor complexalphav-beta5 integrin-vitronectin complexATP-sensitive potassium channel complexBMP receptor complexCD40 receptor complexciliary neurotrophic factor receptor complexglycine-gated chloride channel complexgranulocyte macrophage colony-stimulating factor receptor complexhigh molecular weight kininogen receptor complexhistamine-gated chloride channel complexhydrogen:potassium-exchanging ATPase complexinsulin receptor complexintegral to external side of plasma membraneintegral to muscle cell projection membraneintegrin complex +interleukin-1 receptor complexinterleukin-12 receptor complexinterleukin-13 receptor complexinterleukin-18 receptor complexinterleukin-2 receptor complexinterleukin-20 receptor complexinterleukin-23 receptor complexinterleukin-28 receptor complexinterleukin-3 receptor complexinterleukin-4 receptor complexinterleukin-5 receptor complexinterleukin-6 receptor complexinterleukin-9 receptor complexionotropic glutamate receptor complex +membrane attack complexNADPH oxidase complexoncostatin-M receptor complexplasma membrane proton-transporting V-type ATPase, V0 domainplasma membrane proton-transporting V-type ATPase, V1 domainpre-T cell receptor complexSC5b-7 complexsodium:potassium-exchanging ATPase complexsucrase-isomaltase complextransforming growth factor beta receptor homodimeric complex +voltage-gated potassium channel complex +voltage-gated sodium channel complexintrinsic to external side of plasma membrane +intrinsic to internal side of plasma membranecellular_componentcellcell partplasma membrane partintrinsic to plasma membraneanchored to plasma membrane +integral to plasma membrane [GO:0005887] (692 genes, 793 annotations)acetylcholine-gated channel complexactivin receptor complexalphav-beta5 integrin-vitronectin complexATP-sensitive potassium channel complexBMP receptor complexCD40 receptor complexciliary neurotrophic factor receptor complexglycine-gated chloride channel complexgranulocyte macrophage colony-stimulating factor receptor complexhigh molecular weight kininogen receptor complexhistamine-gated chloride channel complexhydrogen:potassium-exchanging ATPase complexinsulin receptor complexintegral to external side of plasma membraneintegral to muscle cell projection membraneintegrin complex +interleukin-1 receptor complexinterleukin-12 receptor complexinterleukin-13 receptor complexinterleukin-18 receptor complexinterleukin-2 receptor complexinterleukin-20 receptor complexinterleukin-23 receptor complexinterleukin-28 receptor complexinterleukin-3 receptor complexinterleukin-4 receptor complexinterleukin-5 receptor complexinterleukin-6 receptor complexinterleukin-9 receptor complexionotropic glutamate receptor complex +membrane attack complexNADPH oxidase complexoncostatin-M receptor complexplasma membrane proton-transporting V-type ATPase, V0 domainplasma membrane proton-transporting V-type ATPase, V1 domainpre-T cell receptor complexSC5b-7 complexsodium:potassium-exchanging ATPase complexsucrase-isomaltase complextransforming growth factor beta receptor homodimeric complex +voltage-gated potassium channel complex +voltage-gated sodium channel complexintrinsic to external side of plasma membrane +intrinsic to internal side of plasma membranecellular_componentcell partcell peripheryplasma membraneplasma membrane partintrinsic to plasma membraneanchored to plasma membrane +integral to plasma membrane [GO:0005887] (692 genes, 793 annotations)acetylcholine-gated channel complexactivin receptor complexalphav-beta5 integrin-vitronectin complexATP-sensitive potassium channel complexBMP receptor complexCD40 receptor complexciliary neurotrophic factor receptor complexglycine-gated chloride channel complexgranulocyte macrophage colony-stimulating factor receptor complexhigh molecular weight kininogen receptor complexhistamine-gated chloride channel complexhydrogen:potassium-exchanging ATPase complexinsulin receptor complexintegral to external side of plasma membraneintegral to muscle cell projection membraneintegrin complex +interleukin-1 receptor complexinterleukin-12 receptor complexinterleukin-13 receptor complexinterleukin-18 receptor complexinterleukin-2 receptor complexinterleukin-20 receptor complexinterleukin-23 receptor complexinterleukin-28 receptor complexinterleukin-3 receptor complexinterleukin-4 receptor complexinterleukin-5 receptor complexinterleukin-6 receptor complexinterleukin-9 receptor complexionotropic glutamate receptor complex +membrane attack complexNADPH oxidase complexoncostatin-M receptor complexplasma membrane proton-transporting V-type ATPase, V0 domainplasma membrane proton-transporting V-type ATPase, V1 domainpre-T cell receptor complexSC5b-7 complexsodium:potassium-exchanging ATPase complexsucrase-isomaltase complextransforming growth factor beta receptor homodimeric complex +voltage-gated potassium channel complex +voltage-gated sodium channel complexintrinsic to external side of plasma membrane +intrinsic to internal side of plasma membranecellular_componentcell partplasma membraneplasma membrane partintrinsic to plasma membraneanchored to plasma membrane +integral to plasma membrane [GO:0005887] (692 genes, 793 annotations)acetylcholine-gated channel complexactivin receptor complexalphav-beta5 integrin-vitronectin complexATP-sensitive potassium channel complexBMP receptor complexCD40 receptor complexciliary neurotrophic factor receptor complexglycine-gated chloride channel complexgranulocyte macrophage colony-stimulating factor receptor complexhigh molecular weight kininogen receptor complexhistamine-gated chloride channel complexhydrogen:potassium-exchanging ATPase complexinsulin receptor complexintegral to external side of plasma membraneintegral to muscle cell projection membraneintegrin complex +interleukin-1 receptor complexinterleukin-12 receptor complexinterleukin-13 receptor complexinterleukin-18 receptor complexinterleukin-2 receptor complexinterleukin-20 receptor complexinterleukin-23 receptor complexinterleukin-28 receptor complexinterleukin-3 receptor complexinterleukin-4 receptor complexinterleukin-5 receptor complexinterleukin-6 receptor complexinterleukin-9 receptor complexionotropic glutamate receptor complex +membrane attack complexNADPH oxidase complexoncostatin-M receptor complexplasma membrane proton-transporting V-type ATPase, V0 domainplasma membrane proton-transporting V-type ATPase, V1 domainpre-T cell receptor complexSC5b-7 complexsodium:potassium-exchanging ATPase complexsucrase-isomaltase complextransforming growth factor beta receptor homodimeric complex +voltage-gated potassium channel complex +voltage-gated sodium channel complexintrinsic to external side of plasma membrane +intrinsic to internal side of plasma membranecellular_componentcell partplasma membrane partintrinsic to plasma membraneanchored to plasma membrane +integral to plasma membrane [GO:0005887] (692 genes, 793 annotations)acetylcholine-gated channel complexactivin receptor complexalphav-beta5 integrin-vitronectin complexATP-sensitive potassium channel complexBMP receptor complexCD40 receptor complexciliary neurotrophic factor receptor complexglycine-gated chloride channel complexgranulocyte macrophage colony-stimulating factor receptor complexhigh molecular weight kininogen receptor complexhistamine-gated chloride channel complexhydrogen:potassium-exchanging ATPase complexinsulin receptor complexintegral to external side of plasma membraneintegral to muscle cell projection membraneintegrin complex +interleukin-1 receptor complexinterleukin-12 receptor complexinterleukin-13 receptor complexinterleukin-18 receptor complexinterleukin-2 receptor complexinterleukin-20 receptor complexinterleukin-23 receptor complexinterleukin-28 receptor complexinterleukin-3 receptor complexinterleukin-4 receptor complexinterleukin-5 receptor complexinterleukin-6 receptor complexinterleukin-9 receptor complexionotropic glutamate receptor complex +membrane attack complexNADPH oxidase complexoncostatin-M receptor complexplasma membrane proton-transporting V-type ATPase, V0 domainplasma membrane proton-transporting V-type ATPase, V1 domainpre-T cell receptor complexSC5b-7 complexsodium:potassium-exchanging ATPase complexsucrase-isomaltase complextransforming growth factor beta receptor homodimeric complex +voltage-gated potassium channel complex +voltage-gated sodium channel complexintrinsic to external side of plasma membrane +intrinsic to internal side of plasma membranecellular_componentmembranemembrane partintrinsic to membraneintegral to membranecytochrome o ubiquinol oxidase complexintegral to cell outer membraneintegral to organelle membrane +integral to plasma membrane [GO:0005887] (692 genes, 793 annotations)acetylcholine-gated channel complexactivin receptor complexalphav-beta5 integrin-vitronectin complexATP-sensitive potassium channel complexBMP receptor complexCD40 receptor complexciliary neurotrophic factor receptor complexglycine-gated chloride channel complexgranulocyte macrophage colony-stimulating factor receptor complexhigh molecular weight kininogen receptor complexhistamine-gated chloride channel complexhydrogen:potassium-exchanging ATPase complexinsulin receptor complexintegral to external side of plasma membraneintegral to muscle cell projection membraneintegrin complex +interleukin-1 receptor complexinterleukin-12 receptor complexinterleukin-13 receptor complexinterleukin-18 receptor complexinterleukin-2 receptor complexinterleukin-20 receptor complexinterleukin-23 receptor complexinterleukin-28 receptor complexinterleukin-3 receptor complexinterleukin-4 receptor complexinterleukin-5 receptor complexinterleukin-6 receptor complexinterleukin-9 receptor complexionotropic glutamate receptor complex +membrane attack complexNADPH oxidase complexoncostatin-M receptor complexplasma membrane proton-transporting V-type ATPase, V0 domainplasma membrane proton-transporting V-type ATPase, V1 domainpre-T cell receptor complexSC5b-7 complexsodium:potassium-exchanging ATPase complexsucrase-isomaltase complextransforming growth factor beta receptor homodimeric complex +voltage-gated potassium channel complex +voltage-gated sodium channel complexintegral to thylakoid membraneion channel complex +lipopolysaccharide receptor complexmeprin A complexpore complex +sodium ion-transporting two-sector ATPase complex +cellular_componentmembranemembrane partintrinsic to membraneintrinsic to plasma membraneanchored to plasma membrane +integral to plasma membrane [GO:0005887] (692 genes, 793 annotations)acetylcholine-gated channel complexactivin receptor complexalphav-beta5 integrin-vitronectin complexATP-sensitive potassium channel complexBMP receptor complexCD40 receptor complexciliary neurotrophic factor receptor complexglycine-gated chloride channel complexgranulocyte macrophage colony-stimulating factor receptor complexhigh molecular weight kininogen receptor complexhistamine-gated chloride channel complexhydrogen:potassium-exchanging ATPase complexinsulin receptor complexintegral to external side of plasma membraneintegral to muscle cell projection membraneintegrin complex +interleukin-1 receptor complexinterleukin-12 receptor complexinterleukin-13 receptor complexinterleukin-18 receptor complexinterleukin-2 receptor complexinterleukin-20 receptor complexinterleukin-23 receptor complexinterleukin-28 receptor complexinterleukin-3 receptor complexinterleukin-4 receptor complexinterleukin-5 receptor complexinterleukin-6 receptor complexinterleukin-9 receptor complexionotropic glutamate receptor complex +membrane attack complexNADPH oxidase complexoncostatin-M receptor complexplasma membrane proton-transporting V-type ATPase, V0 domainplasma membrane proton-transporting V-type ATPase, V1 domainpre-T cell receptor complexSC5b-7 complexsodium:potassium-exchanging ATPase complexsucrase-isomaltase complextransforming growth factor beta receptor homodimeric complex +voltage-gated potassium channel complex +voltage-gated sodium channel complexintrinsic to external side of plasma membrane +intrinsic to internal side of plasma membranecellular_componentmembranemembrane partplasma membrane partintrinsic to plasma membraneanchored to plasma membrane +integral to plasma membrane [GO:0005887] (692 genes, 793 annotations)acetylcholine-gated channel complexactivin receptor complexalphav-beta5 integrin-vitronectin complexATP-sensitive potassium channel complexBMP receptor complexCD40 receptor complexciliary neurotrophic factor receptor complexglycine-gated chloride channel complexgranulocyte macrophage colony-stimulating factor receptor complexhigh molecular weight kininogen receptor complexhistamine-gated chloride channel complexhydrogen:potassium-exchanging ATPase complexinsulin receptor complexintegral to external side of plasma membraneintegral to muscle cell projection membraneintegrin complex +interleukin-1 receptor complexinterleukin-12 receptor complexinterleukin-13 receptor complexinterleukin-18 receptor complexinterleukin-2 receptor complexinterleukin-20 receptor complexinterleukin-23 receptor complexinterleukin-28 receptor complexinterleukin-3 receptor complexinterleukin-4 receptor complexinterleukin-5 receptor complexinterleukin-6 receptor complexinterleukin-9 receptor complexionotropic glutamate receptor complex +membrane attack complexNADPH oxidase complexoncostatin-M receptor complexplasma membrane proton-transporting V-type ATPase, V0 domainplasma membrane proton-transporting V-type ATPase, V1 domainpre-T cell receptor complexSC5b-7 complexsodium:potassium-exchanging ATPase complexsucrase-isomaltase complextransforming growth factor beta receptor homodimeric complex +voltage-gated potassium channel complex +voltage-gated sodium channel complexintrinsic to external side of plasma membrane +intrinsic to internal side of plasma membranecellular_componentmembraneplasma membraneplasma membrane partintrinsic to plasma membraneanchored to plasma membrane +integral to plasma membrane [GO:0005887] (692 genes, 793 annotations)acetylcholine-gated channel complexactivin receptor complexalphav-beta5 integrin-vitronectin complexATP-sensitive potassium channel complexBMP receptor complexCD40 receptor complexciliary neurotrophic factor receptor complexglycine-gated chloride channel complexgranulocyte macrophage colony-stimulating factor receptor complexhigh molecular weight kininogen receptor complexhistamine-gated chloride channel complexhydrogen:potassium-exchanging ATPase complexinsulin receptor complexintegral to external side of plasma membraneintegral to muscle cell projection membraneintegrin complex +interleukin-1 receptor complexinterleukin-12 receptor complexinterleukin-13 receptor complexinterleukin-18 receptor complexinterleukin-2 receptor complexinterleukin-20 receptor complexinterleukin-23 receptor complexinterleukin-28 receptor complexinterleukin-3 receptor complexinterleukin-4 receptor complexinterleukin-5 receptor complexinterleukin-6 receptor complexinterleukin-9 receptor complexionotropic glutamate receptor complex +membrane attack complexNADPH oxidase complexoncostatin-M receptor complexplasma membrane proton-transporting V-type ATPase, V0 domainplasma membrane proton-transporting V-type ATPase, V1 domainpre-T cell receptor complexSC5b-7 complexsodium:potassium-exchanging ATPase complexsucrase-isomaltase complextransforming growth factor beta receptor homodimeric complex +voltage-gated potassium channel complex +voltage-gated sodium channel complexintrinsic to external side of plasma membrane +intrinsic to internal side of plasma membranecellular_componentmembrane partintrinsic to membraneintegral to membranecytochrome o ubiquinol oxidase complexintegral to cell outer membraneintegral to organelle membrane +integral to plasma membrane [GO:0005887] (692 genes, 793 annotations)acetylcholine-gated channel complexactivin receptor complexalphav-beta5 integrin-vitronectin complexATP-sensitive potassium channel complexBMP receptor complexCD40 receptor complexciliary neurotrophic factor receptor complexglycine-gated chloride channel complexgranulocyte macrophage colony-stimulating factor receptor complexhigh molecular weight kininogen receptor complexhistamine-gated chloride channel complexhydrogen:potassium-exchanging ATPase complexinsulin receptor complexintegral to external side of plasma membraneintegral to muscle cell projection membraneintegrin complex +interleukin-1 receptor complexinterleukin-12 receptor complexinterleukin-13 receptor complexinterleukin-18 receptor complexinterleukin-2 receptor complexinterleukin-20 receptor complexinterleukin-23 receptor complexinterleukin-28 receptor complexinterleukin-3 receptor complexinterleukin-4 receptor complexinterleukin-5 receptor complexinterleukin-6 receptor complexinterleukin-9 receptor complexionotropic glutamate receptor complex +membrane attack complexNADPH oxidase complexoncostatin-M receptor complexplasma membrane proton-transporting V-type ATPase, V0 domainplasma membrane proton-transporting V-type ATPase, V1 domainpre-T cell receptor complexSC5b-7 complexsodium:potassium-exchanging ATPase complexsucrase-isomaltase complextransforming growth factor beta receptor homodimeric complex +voltage-gated potassium channel complex +voltage-gated sodium channel complexintegral to thylakoid membraneion channel complex +lipopolysaccharide receptor complexmeprin A complexpore complex +sodium ion-transporting two-sector ATPase complex +cellular_componentmembrane partintrinsic to membraneintrinsic to plasma membraneanchored to plasma membrane +integral to plasma membrane [GO:0005887] (692 genes, 793 annotations)acetylcholine-gated channel complexactivin receptor complexalphav-beta5 integrin-vitronectin complexATP-sensitive potassium channel complexBMP receptor complexCD40 receptor complexciliary neurotrophic factor receptor complexglycine-gated chloride channel complexgranulocyte macrophage colony-stimulating factor receptor complexhigh molecular weight kininogen receptor complexhistamine-gated chloride channel complexhydrogen:potassium-exchanging ATPase complexinsulin receptor complexintegral to external side of plasma membraneintegral to muscle cell projection membraneintegrin complex +interleukin-1 receptor complexinterleukin-12 receptor complexinterleukin-13 receptor complexinterleukin-18 receptor complexinterleukin-2 receptor complexinterleukin-20 receptor complexinterleukin-23 receptor complexinterleukin-28 receptor complexinterleukin-3 receptor complexinterleukin-4 receptor complexinterleukin-5 receptor complexinterleukin-6 receptor complexinterleukin-9 receptor complexionotropic glutamate receptor complex +membrane attack complexNADPH oxidase complexoncostatin-M receptor complexplasma membrane proton-transporting V-type ATPase, V0 domainplasma membrane proton-transporting V-type ATPase, V1 domainpre-T cell receptor complexSC5b-7 complexsodium:potassium-exchanging ATPase complexsucrase-isomaltase complextransforming growth factor beta receptor homodimeric complex +voltage-gated potassium channel complex +voltage-gated sodium channel complexintrinsic to external side of plasma membrane +intrinsic to internal side of plasma membranecellular_componentmembrane partplasma membrane partintrinsic to plasma membraneanchored to plasma membrane +integral to plasma membrane [GO:0005887] (692 genes, 793 annotations)acetylcholine-gated channel complexactivin receptor complexalphav-beta5 integrin-vitronectin complexATP-sensitive potassium channel complexBMP receptor complexCD40 receptor complexciliary neurotrophic factor receptor complexglycine-gated chloride channel complexgranulocyte macrophage colony-stimulating factor receptor complexhigh molecular weight kininogen receptor complexhistamine-gated chloride channel complexhydrogen:potassium-exchanging ATPase complexinsulin receptor complexintegral to external side of plasma membraneintegral to muscle cell projection membraneintegrin complex +interleukin-1 receptor complexinterleukin-12 receptor complexinterleukin-13 receptor complexinterleukin-18 receptor complexinterleukin-2 receptor complexinterleukin-20 receptor complexinterleukin-23 receptor complexinterleukin-28 receptor complexinterleukin-3 receptor complexinterleukin-4 receptor complexinterleukin-5 receptor complexinterleukin-6 receptor complexinterleukin-9 receptor complexionotropic glutamate receptor complex +membrane attack complexNADPH oxidase complexoncostatin-M receptor complexplasma membrane proton-transporting V-type ATPase, V0 domainplasma membrane proton-transporting V-type ATPase, V1 domainpre-T cell receptor complexSC5b-7 complexsodium:potassium-exchanging ATPase complexsucrase-isomaltase complextransforming growth factor beta receptor homodimeric complex +voltage-gated potassium channel complex +voltage-gated sodium channel complexintrinsic to external side of plasma membrane +intrinsic to internal side of plasma membraneMouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc |
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last database update 05/08/2013 MGI 5.13 |
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