| GO term: | extracellular ATP-gated cation channel activity |
| Synonym: | P2X receptor |
| Synonym: | purinoceptor |
| Synonym: | purinoreceptor |
| GO id: | GO:0004931 |
| Definition: | Catalysis of the transmembrane transfer of a cation by a channel that opens when extracellular ATP has been bound by the channel complex or one of its constituent parts. |
| Comments | Note that this term refers to an activity and not a gene product. Consider also annotating to the molecular function term 'purinergic nucleotide receptor activity ; GO:0001614'. |
| Number of paths to term: | 25 |
denotes an 'is-a' relationship
denotes a 'part-of' relationship
denotes a 'regulates' relationship
denotes a 'positively-regulates' relationship
denotes a 'negatively-regulates' relationship
molecular_functiontransporter activitysubstrate-specific transporter activitysubstrate-specific transmembrane transporter activityion transmembrane transporter activitycation transmembrane transporter activitycation channel activityacetylcholine-activated cation-selective channel activityammonium channel activitycalcium activated cation channel activity +calcium channel activity +extracellular ATP-gated cation channel activity [GO:0004931] (7 genes, 19 annotations)hydrogen ion channel activity +intracellular cyclic nucleotide activated cation channel activity +potassium channel activity +serotonin-activated cation-selective channel activitysodium channel activity +voltage-gated cation channel activity +zinc efflux active transmembrane transporter activitymolecular_functiontransporter activitysubstrate-specific transporter activitysubstrate-specific transmembrane transporter activityion transmembrane transporter activityion channel activitycation channel activityacetylcholine-activated cation-selective channel activityammonium channel activitycalcium activated cation channel activity +calcium channel activity +extracellular ATP-gated cation channel activity [GO:0004931] (7 genes, 19 annotations)hydrogen ion channel activity +intracellular cyclic nucleotide activated cation channel activity +potassium channel activity +serotonin-activated cation-selective channel activitysodium channel activity +voltage-gated cation channel activity +zinc efflux active transmembrane transporter activitymolecular_functiontransporter activitysubstrate-specific transporter activitysubstrate-specific transmembrane transporter activityion transmembrane transporter activityion channel activityligand-gated ion channel activityATP-gated ion channel activityextracellular ATP-gated cation channel activity [GO:0004931] (7 genes, 19 annotations)molecular_functiontransporter activitysubstrate-specific transporter activitysubstrate-specific transmembrane transporter activityion transmembrane transporter activityion channel activityligand-gated ion channel activityextracellular ligand-gated ion channel activityexcitatory extracellular ligand-gated ion channel activityacetylcholine-activated cation-selective channel activityextracellular ATP-gated cation channel activity [GO:0004931] (7 genes, 19 annotations)extracellular-glutamate-gated ion channel activity +extracellular-glycine-gated ion channel activity +serotonin-activated cation-selective channel activitymolecular_functiontransporter activitysubstrate-specific transporter activitysubstrate-specific transmembrane transporter activityion transmembrane transporter activityion gated channel activityligand-gated ion channel activityATP-gated ion channel activityextracellular ATP-gated cation channel activity [GO:0004931] (7 genes, 19 annotations)molecular_functiontransporter activitysubstrate-specific transporter activitysubstrate-specific transmembrane transporter activityion transmembrane transporter activityion gated channel activityligand-gated ion channel activityextracellular ligand-gated ion channel activityexcitatory extracellular ligand-gated ion channel activityacetylcholine-activated cation-selective channel activityextracellular ATP-gated cation channel activity [GO:0004931] (7 genes, 19 annotations)extracellular-glutamate-gated ion channel activity +extracellular-glycine-gated ion channel activity +serotonin-activated cation-selective channel activitymolecular_functiontransporter activitysubstrate-specific transporter activitysubstrate-specific transmembrane transporter activitysubstrate-specific channel activityion channel activitycation channel activityacetylcholine-activated cation-selective channel activityammonium channel activitycalcium activated cation channel activity +calcium channel activity +extracellular ATP-gated cation channel activity [GO:0004931] (7 genes, 19 annotations)hydrogen ion channel activity +intracellular cyclic nucleotide activated cation channel activity +potassium channel activity +serotonin-activated cation-selective channel activitysodium channel activity +voltage-gated cation channel activity +zinc efflux active transmembrane transporter activitymolecular_functiontransporter activitysubstrate-specific transporter activitysubstrate-specific transmembrane transporter activitysubstrate-specific channel activityion channel activityligand-gated ion channel activityATP-gated ion channel activityextracellular ATP-gated cation channel activity [GO:0004931] (7 genes, 19 annotations)molecular_functiontransporter activitysubstrate-specific transporter activitysubstrate-specific transmembrane transporter activitysubstrate-specific channel activityion channel activityligand-gated ion channel activityextracellular ligand-gated ion channel activityexcitatory extracellular ligand-gated ion channel activityacetylcholine-activated cation-selective channel activityextracellular ATP-gated cation channel activity [GO:0004931] (7 genes, 19 annotations)extracellular-glutamate-gated ion channel activity +extracellular-glycine-gated ion channel activity +serotonin-activated cation-selective channel activitymolecular_functiontransporter activitytransmembrane transporter activitypassive transmembrane transporter activitychannel activitygated channel activityion gated channel activityligand-gated ion channel activityATP-gated ion channel activityextracellular ATP-gated cation channel activity [GO:0004931] (7 genes, 19 annotations)molecular_functiontransporter activitytransmembrane transporter activitypassive transmembrane transporter activitychannel activitygated channel activityion gated channel activityligand-gated ion channel activityextracellular ligand-gated ion channel activityexcitatory extracellular ligand-gated ion channel activityacetylcholine-activated cation-selective channel activityextracellular ATP-gated cation channel activity [GO:0004931] (7 genes, 19 annotations)extracellular-glutamate-gated ion channel activity +extracellular-glycine-gated ion channel activity +serotonin-activated cation-selective channel activitymolecular_functiontransporter activitytransmembrane transporter activitypassive transmembrane transporter activitychannel activitygated channel activityligand-gated channel activityligand-gated ion channel activityATP-gated ion channel activityextracellular ATP-gated cation channel activity [GO:0004931] (7 genes, 19 annotations)molecular_functiontransporter activitytransmembrane transporter activitypassive transmembrane transporter activitychannel activitygated channel activityligand-gated channel activityligand-gated ion channel activityextracellular ligand-gated ion channel activityexcitatory extracellular ligand-gated ion channel activityacetylcholine-activated cation-selective channel activityextracellular ATP-gated cation channel activity [GO:0004931] (7 genes, 19 annotations)extracellular-glutamate-gated ion channel activity +extracellular-glycine-gated ion channel activity +serotonin-activated cation-selective channel activitymolecular_functiontransporter activitytransmembrane transporter activitypassive transmembrane transporter activitychannel activitysubstrate-specific channel activityion channel activitycation channel activityacetylcholine-activated cation-selective channel activityammonium channel activitycalcium activated cation channel activity +calcium channel activity +extracellular ATP-gated cation channel activity [GO:0004931] (7 genes, 19 annotations)hydrogen ion channel activity +intracellular cyclic nucleotide activated cation channel activity +potassium channel activity +serotonin-activated cation-selective channel activitysodium channel activity +voltage-gated cation channel activity +zinc efflux active transmembrane transporter activitymolecular_functiontransporter activitytransmembrane transporter activitypassive transmembrane transporter activitychannel activitysubstrate-specific channel activityion channel activityligand-gated ion channel activityATP-gated ion channel activityextracellular ATP-gated cation channel activity [GO:0004931] (7 genes, 19 annotations)molecular_functiontransporter activitytransmembrane transporter activitypassive transmembrane transporter activitychannel activitysubstrate-specific channel activityion channel activityligand-gated ion channel activityextracellular ligand-gated ion channel activityexcitatory extracellular ligand-gated ion channel activityacetylcholine-activated cation-selective channel activityextracellular ATP-gated cation channel activity [GO:0004931] (7 genes, 19 annotations)extracellular-glutamate-gated ion channel activity +extracellular-glycine-gated ion channel activity +serotonin-activated cation-selective channel activitymolecular_functiontransporter activitytransmembrane transporter activitysubstrate-specific transmembrane transporter activityion transmembrane transporter activitycation transmembrane transporter activitycation channel activityacetylcholine-activated cation-selective channel activityammonium channel activitycalcium activated cation channel activity +calcium channel activity +extracellular ATP-gated cation channel activity [GO:0004931] (7 genes, 19 annotations)hydrogen ion channel activity +intracellular cyclic nucleotide activated cation channel activity +potassium channel activity +serotonin-activated cation-selective channel activitysodium channel activity +voltage-gated cation channel activity +zinc efflux active transmembrane transporter activitymolecular_functiontransporter activitytransmembrane transporter activitysubstrate-specific transmembrane transporter activityion transmembrane transporter activityion channel activitycation channel activityacetylcholine-activated cation-selective channel activityammonium channel activitycalcium activated cation channel activity +calcium channel activity +extracellular ATP-gated cation channel activity [GO:0004931] (7 genes, 19 annotations)hydrogen ion channel activity +intracellular cyclic nucleotide activated cation channel activity +potassium channel activity +serotonin-activated cation-selective channel activitysodium channel activity +voltage-gated cation channel activity +zinc efflux active transmembrane transporter activitymolecular_functiontransporter activitytransmembrane transporter activitysubstrate-specific transmembrane transporter activityion transmembrane transporter activityion channel activityligand-gated ion channel activityATP-gated ion channel activityextracellular ATP-gated cation channel activity [GO:0004931] (7 genes, 19 annotations)molecular_functiontransporter activitytransmembrane transporter activitysubstrate-specific transmembrane transporter activityion transmembrane transporter activityion channel activityligand-gated ion channel activityextracellular ligand-gated ion channel activityexcitatory extracellular ligand-gated ion channel activityacetylcholine-activated cation-selective channel activityextracellular ATP-gated cation channel activity [GO:0004931] (7 genes, 19 annotations)extracellular-glutamate-gated ion channel activity +extracellular-glycine-gated ion channel activity +serotonin-activated cation-selective channel activitymolecular_functiontransporter activitytransmembrane transporter activitysubstrate-specific transmembrane transporter activityion transmembrane transporter activityion gated channel activityligand-gated ion channel activityATP-gated ion channel activityextracellular ATP-gated cation channel activity [GO:0004931] (7 genes, 19 annotations)molecular_functiontransporter activitytransmembrane transporter activitysubstrate-specific transmembrane transporter activityion transmembrane transporter activityion gated channel activityligand-gated ion channel activityextracellular ligand-gated ion channel activityexcitatory extracellular ligand-gated ion channel activityacetylcholine-activated cation-selective channel activityextracellular ATP-gated cation channel activity [GO:0004931] (7 genes, 19 annotations)extracellular-glutamate-gated ion channel activity +extracellular-glycine-gated ion channel activity +serotonin-activated cation-selective channel activitymolecular_functiontransporter activitytransmembrane transporter activitysubstrate-specific transmembrane transporter activitysubstrate-specific channel activityion channel activitycation channel activityacetylcholine-activated cation-selective channel activityammonium channel activitycalcium activated cation channel activity +calcium channel activity +extracellular ATP-gated cation channel activity [GO:0004931] (7 genes, 19 annotations)hydrogen ion channel activity +intracellular cyclic nucleotide activated cation channel activity +potassium channel activity +serotonin-activated cation-selective channel activitysodium channel activity +voltage-gated cation channel activity +zinc efflux active transmembrane transporter activitymolecular_functiontransporter activitytransmembrane transporter activitysubstrate-specific transmembrane transporter activitysubstrate-specific channel activityion channel activityligand-gated ion channel activityATP-gated ion channel activityextracellular ATP-gated cation channel activity [GO:0004931] (7 genes, 19 annotations)molecular_functiontransporter activitytransmembrane transporter activitysubstrate-specific transmembrane transporter activitysubstrate-specific channel activityion channel activityligand-gated ion channel activityextracellular ligand-gated ion channel activityexcitatory extracellular ligand-gated ion channel activityacetylcholine-activated cation-selective channel activityextracellular ATP-gated cation channel activity [GO:0004931] (7 genes, 19 annotations)extracellular-glutamate-gated ion channel activity +extracellular-glycine-gated ion channel activity +serotonin-activated cation-selective channel activityMouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc |
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last database update 05/08/2013 MGI 5.13 |
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