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Gene Ontology Browser
Term Detail
GO term:extracellular ATP-gated cation channel activity
Synonym: P2X receptor
Synonym: purinoceptor
Synonym: purinoreceptor
GO id:GO:0004931
Definition:Catalysis of the transmembrane transfer of a cation by a channel that opens when extracellular ATP has been bound by the channel complex or one of its constituent parts.
CommentsNote that this term refers to an activity and not a gene product. Consider also annotating to the molecular function term 'purinergic nucleotide receptor activity ; GO:0001614'.
Number of paths to term: 19

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-amolecular_function
                is-atransporter activity
                        is-asubstrate-specific transporter activity
                                is-asubstrate-specific transmembrane transporter activity
                                        is-aion transmembrane transporter activity
                                                is-acation transmembrane transporter activity
                                                        is-acation channel activity
                                                                is-aacetylcholine-activated cation-selective channel activity
                                                                is-aammonium channel activity
                                                                is-acalcium activated cation channel activity +
                                                                is-acalcium channel activity +
                                                                is-aextracellular ATP-gated cation channel activity [GO:0004931] (7 genes, 19 annotations)
                                                                is-ahydrogen ion channel activity +
                                                                is-aintracellular cyclic nucleotide activated cation channel activity +
                                                                is-amethylammonium channel activity
                                                                is-apotassium channel activity +
                                                                is-aserotonin-activated cation-selective channel activity
                                                                is-asodium channel activity +
                                                                is-atemperature-gated cation channel activity
                                                                is-avoltage-gated cation channel activity +
                                                                is-azinc efflux active transmembrane transporter activity


Gene_Ontology
        is-amolecular_function
                is-atransporter activity
                        is-asubstrate-specific transporter activity
                                is-asubstrate-specific transmembrane transporter activity
                                        is-aion transmembrane transporter activity
                                                is-aion channel activity
                                                        is-acation channel activity
                                                                is-aacetylcholine-activated cation-selective channel activity
                                                                is-aammonium channel activity
                                                                is-acalcium activated cation channel activity +
                                                                is-acalcium channel activity +
                                                                is-aextracellular ATP-gated cation channel activity [GO:0004931] (7 genes, 19 annotations)
                                                                is-ahydrogen ion channel activity +
                                                                is-aintracellular cyclic nucleotide activated cation channel activity +
                                                                is-amethylammonium channel activity
                                                                is-apotassium channel activity +
                                                                is-aserotonin-activated cation-selective channel activity
                                                                is-asodium channel activity +
                                                                is-atemperature-gated cation channel activity
                                                                is-avoltage-gated cation channel activity +
                                                                is-azinc efflux active transmembrane transporter activity


Gene_Ontology
        is-amolecular_function
                is-atransporter activity
                        is-asubstrate-specific transporter activity
                                is-asubstrate-specific transmembrane transporter activity
                                        is-aion transmembrane transporter activity
                                                is-aion channel activity
                                                        is-aligand-gated ion channel activity
                                                                is-aATP-gated ion channel activity
                                                                        is-aextracellular ATP-gated cation channel activity [GO:0004931] (7 genes, 19 annotations)


Gene_Ontology
        is-amolecular_function
                is-atransporter activity
                        is-asubstrate-specific transporter activity
                                is-asubstrate-specific transmembrane transporter activity
                                        is-aion transmembrane transporter activity
                                                is-aion channel activity
                                                        is-aligand-gated ion channel activity
                                                                is-aextracellular ligand-gated ion channel activity
                                                                        is-aexcitatory extracellular ligand-gated ion channel activity
                                                                                is-aacetylcholine-activated cation-selective channel activity
                                                                                is-aextracellular ATP-gated cation channel activity [GO:0004931] (7 genes, 19 annotations)
                                                                                is-aextracellular-glutamate-gated ion channel activity +
                                                                                is-aextracellular-glycine-gated ion channel activity +
                                                                                is-aserotonin-activated cation-selective channel activity


Gene_Ontology
        is-amolecular_function
                is-atransporter activity
                        is-asubstrate-specific transporter activity
                                is-asubstrate-specific transmembrane transporter activity
                                        is-asubstrate-specific channel activity
                                                is-aion channel activity
                                                        is-acation channel activity
                                                                is-aacetylcholine-activated cation-selective channel activity
                                                                is-aammonium channel activity
                                                                is-acalcium activated cation channel activity +
                                                                is-acalcium channel activity +
                                                                is-aextracellular ATP-gated cation channel activity [GO:0004931] (7 genes, 19 annotations)
                                                                is-ahydrogen ion channel activity +
                                                                is-aintracellular cyclic nucleotide activated cation channel activity +
                                                                is-amethylammonium channel activity
                                                                is-apotassium channel activity +
                                                                is-aserotonin-activated cation-selective channel activity
                                                                is-asodium channel activity +
                                                                is-atemperature-gated cation channel activity
                                                                is-avoltage-gated cation channel activity +
                                                                is-azinc efflux active transmembrane transporter activity


Gene_Ontology
        is-amolecular_function
                is-atransporter activity
                        is-asubstrate-specific transporter activity
                                is-asubstrate-specific transmembrane transporter activity
                                        is-asubstrate-specific channel activity
                                                is-aion channel activity
                                                        is-aligand-gated ion channel activity
                                                                is-aATP-gated ion channel activity
                                                                        is-aextracellular ATP-gated cation channel activity [GO:0004931] (7 genes, 19 annotations)


Gene_Ontology
        is-amolecular_function
                is-atransporter activity
                        is-asubstrate-specific transporter activity
                                is-asubstrate-specific transmembrane transporter activity
                                        is-asubstrate-specific channel activity
                                                is-aion channel activity
                                                        is-aligand-gated ion channel activity
                                                                is-aextracellular ligand-gated ion channel activity
                                                                        is-aexcitatory extracellular ligand-gated ion channel activity
                                                                                is-aacetylcholine-activated cation-selective channel activity
                                                                                is-aextracellular ATP-gated cation channel activity [GO:0004931] (7 genes, 19 annotations)
                                                                                is-aextracellular-glutamate-gated ion channel activity +
                                                                                is-aextracellular-glycine-gated ion channel activity +
                                                                                is-aserotonin-activated cation-selective channel activity


Gene_Ontology
        is-amolecular_function
                is-atransporter activity
                        is-atransmembrane transporter activity
                                is-apassive transmembrane transporter activity
                                        is-achannel activity
                                                is-agated channel activity
                                                        is-aligand-gated channel activity
                                                                is-aligand-gated ion channel activity
                                                                        is-aATP-gated ion channel activity
                                                                                is-aextracellular ATP-gated cation channel activity [GO:0004931] (7 genes, 19 annotations)


Gene_Ontology
        is-amolecular_function
                is-atransporter activity
                        is-atransmembrane transporter activity
                                is-apassive transmembrane transporter activity
                                        is-achannel activity
                                                is-agated channel activity
                                                        is-aligand-gated channel activity
                                                                is-aligand-gated ion channel activity
                                                                        is-aextracellular ligand-gated ion channel activity
                                                                                is-aexcitatory extracellular ligand-gated ion channel activity
                                                                                        is-aacetylcholine-activated cation-selective channel activity
                                                                                        is-aextracellular ATP-gated cation channel activity [GO:0004931] (7 genes, 19 annotations)
                                                                                        is-aextracellular-glutamate-gated ion channel activity +
                                                                                        is-aextracellular-glycine-gated ion channel activity +
                                                                                        is-aserotonin-activated cation-selective channel activity


Gene_Ontology
        is-amolecular_function
                is-atransporter activity
                        is-atransmembrane transporter activity
                                is-apassive transmembrane transporter activity
                                        is-achannel activity
                                                is-asubstrate-specific channel activity
                                                        is-aion channel activity
                                                                is-acation channel activity
                                                                        is-aacetylcholine-activated cation-selective channel activity
                                                                        is-aammonium channel activity
                                                                        is-acalcium activated cation channel activity +
                                                                        is-acalcium channel activity +
                                                                        is-aextracellular ATP-gated cation channel activity [GO:0004931] (7 genes, 19 annotations)
                                                                        is-ahydrogen ion channel activity +
                                                                        is-aintracellular cyclic nucleotide activated cation channel activity +
                                                                        is-amethylammonium channel activity
                                                                        is-apotassium channel activity +
                                                                        is-aserotonin-activated cation-selective channel activity
                                                                        is-asodium channel activity +
                                                                        is-atemperature-gated cation channel activity
                                                                        is-avoltage-gated cation channel activity +
                                                                        is-azinc efflux active transmembrane transporter activity


Gene_Ontology
        is-amolecular_function
                is-atransporter activity
                        is-atransmembrane transporter activity
                                is-apassive transmembrane transporter activity
                                        is-achannel activity
                                                is-asubstrate-specific channel activity
                                                        is-aion channel activity
                                                                is-aligand-gated ion channel activity
                                                                        is-aATP-gated ion channel activity
                                                                                is-aextracellular ATP-gated cation channel activity [GO:0004931] (7 genes, 19 annotations)


Gene_Ontology
        is-amolecular_function
                is-atransporter activity
                        is-atransmembrane transporter activity
                                is-apassive transmembrane transporter activity
                                        is-achannel activity
                                                is-asubstrate-specific channel activity
                                                        is-aion channel activity
                                                                is-aligand-gated ion channel activity
                                                                        is-aextracellular ligand-gated ion channel activity
                                                                                is-aexcitatory extracellular ligand-gated ion channel activity
                                                                                        is-aacetylcholine-activated cation-selective channel activity
                                                                                        is-aextracellular ATP-gated cation channel activity [GO:0004931] (7 genes, 19 annotations)
                                                                                        is-aextracellular-glutamate-gated ion channel activity +
                                                                                        is-aextracellular-glycine-gated ion channel activity +
                                                                                        is-aserotonin-activated cation-selective channel activity


Gene_Ontology
        is-amolecular_function
                is-atransporter activity
                        is-atransmembrane transporter activity
                                is-asubstrate-specific transmembrane transporter activity
                                        is-aion transmembrane transporter activity
                                                is-acation transmembrane transporter activity
                                                        is-acation channel activity
                                                                is-aacetylcholine-activated cation-selective channel activity
                                                                is-aammonium channel activity
                                                                is-acalcium activated cation channel activity +
                                                                is-acalcium channel activity +
                                                                is-aextracellular ATP-gated cation channel activity [GO:0004931] (7 genes, 19 annotations)
                                                                is-ahydrogen ion channel activity +
                                                                is-aintracellular cyclic nucleotide activated cation channel activity +
                                                                is-amethylammonium channel activity
                                                                is-apotassium channel activity +
                                                                is-aserotonin-activated cation-selective channel activity
                                                                is-asodium channel activity +
                                                                is-atemperature-gated cation channel activity
                                                                is-avoltage-gated cation channel activity +
                                                                is-azinc efflux active transmembrane transporter activity


Gene_Ontology
        is-amolecular_function
                is-atransporter activity
                        is-atransmembrane transporter activity
                                is-asubstrate-specific transmembrane transporter activity
                                        is-aion transmembrane transporter activity
                                                is-aion channel activity
                                                        is-acation channel activity
                                                                is-aacetylcholine-activated cation-selective channel activity
                                                                is-aammonium channel activity
                                                                is-acalcium activated cation channel activity +
                                                                is-acalcium channel activity +
                                                                is-aextracellular ATP-gated cation channel activity [GO:0004931] (7 genes, 19 annotations)
                                                                is-ahydrogen ion channel activity +
                                                                is-aintracellular cyclic nucleotide activated cation channel activity +
                                                                is-amethylammonium channel activity
                                                                is-apotassium channel activity +
                                                                is-aserotonin-activated cation-selective channel activity
                                                                is-asodium channel activity +
                                                                is-atemperature-gated cation channel activity
                                                                is-avoltage-gated cation channel activity +
                                                                is-azinc efflux active transmembrane transporter activity


Gene_Ontology
        is-amolecular_function
                is-atransporter activity
                        is-atransmembrane transporter activity
                                is-asubstrate-specific transmembrane transporter activity
                                        is-aion transmembrane transporter activity
                                                is-aion channel activity
                                                        is-aligand-gated ion channel activity
                                                                is-aATP-gated ion channel activity
                                                                        is-aextracellular ATP-gated cation channel activity [GO:0004931] (7 genes, 19 annotations)


Gene_Ontology
        is-amolecular_function
                is-atransporter activity
                        is-atransmembrane transporter activity
                                is-asubstrate-specific transmembrane transporter activity
                                        is-aion transmembrane transporter activity
                                                is-aion channel activity
                                                        is-aligand-gated ion channel activity
                                                                is-aextracellular ligand-gated ion channel activity
                                                                        is-aexcitatory extracellular ligand-gated ion channel activity
                                                                                is-aacetylcholine-activated cation-selective channel activity
                                                                                is-aextracellular ATP-gated cation channel activity [GO:0004931] (7 genes, 19 annotations)
                                                                                is-aextracellular-glutamate-gated ion channel activity +
                                                                                is-aextracellular-glycine-gated ion channel activity +
                                                                                is-aserotonin-activated cation-selective channel activity


Gene_Ontology
        is-amolecular_function
                is-atransporter activity
                        is-atransmembrane transporter activity
                                is-asubstrate-specific transmembrane transporter activity
                                        is-asubstrate-specific channel activity
                                                is-aion channel activity
                                                        is-acation channel activity
                                                                is-aacetylcholine-activated cation-selective channel activity
                                                                is-aammonium channel activity
                                                                is-acalcium activated cation channel activity +
                                                                is-acalcium channel activity +
                                                                is-aextracellular ATP-gated cation channel activity [GO:0004931] (7 genes, 19 annotations)
                                                                is-ahydrogen ion channel activity +
                                                                is-aintracellular cyclic nucleotide activated cation channel activity +
                                                                is-amethylammonium channel activity
                                                                is-apotassium channel activity +
                                                                is-aserotonin-activated cation-selective channel activity
                                                                is-asodium channel activity +
                                                                is-atemperature-gated cation channel activity
                                                                is-avoltage-gated cation channel activity +
                                                                is-azinc efflux active transmembrane transporter activity


Gene_Ontology
        is-amolecular_function
                is-atransporter activity
                        is-atransmembrane transporter activity
                                is-asubstrate-specific transmembrane transporter activity
                                        is-asubstrate-specific channel activity
                                                is-aion channel activity
                                                        is-aligand-gated ion channel activity
                                                                is-aATP-gated ion channel activity
                                                                        is-aextracellular ATP-gated cation channel activity [GO:0004931] (7 genes, 19 annotations)


Gene_Ontology
        is-amolecular_function
                is-atransporter activity
                        is-atransmembrane transporter activity
                                is-asubstrate-specific transmembrane transporter activity
                                        is-asubstrate-specific channel activity
                                                is-aion channel activity
                                                        is-aligand-gated ion channel activity
                                                                is-aextracellular ligand-gated ion channel activity
                                                                        is-aexcitatory extracellular ligand-gated ion channel activity
                                                                                is-aacetylcholine-activated cation-selective channel activity
                                                                                is-aextracellular ATP-gated cation channel activity [GO:0004931] (7 genes, 19 annotations)
                                                                                is-aextracellular-glutamate-gated ion channel activity +
                                                                                is-aextracellular-glycine-gated ion channel activity +
                                                                                is-aserotonin-activated cation-selective channel activity


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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory