| GO term: | transmembrane receptor protein tyrosine kinase activity |
| Synonym: | anaplastic lymphoma kinase activity |
| Synonym: | ATP:protein-L-tyrosine O-phosphotransferase (receptor-type) activity |
| Synonym: | ATP:protein-tyrosine O-phosphotransferase activity |
| Synonym: | Drosophila Eph kinase activity |
| Synonym: | ephrin-B3 receptor tyrosine kinase activity |
| Synonym: | insulin receptor protein-tyrosine kinase activity |
| Synonym: | neurite outgrowth regulating kinase activity |
| Synonym: | neurotrophin TRKA receptor activity |
| Synonym: | neurotrophin TRKB receptor activity |
| Synonym: | neurotrophin TRKC receptor activity |
| Synonym: | neurotrophin TRK receptor activity |
| Synonym: | novel oncogene with kinase-domain activity |
| Synonym: | receptor protein tyrosine kinase activity |
| Synonym: | receptor protein-tyrosine kinase activity |
| Synonym: | sevenless receptor activity |
| GO id: | GO:0004714 |
| Definition: | Combining with a signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP + a protein-L-tyrosine = ADP + a protein-L-tyrosine phosphate. |
| Number of paths to term: | 6 |
denotes an 'is-a' relationship
denotes a 'part-of' relationship
denotes a 'regulates' relationship
denotes a 'positively-regulates' relationship
denotes a 'negatively-regulates' relationship
molecular_functioncatalytic activitytransferase activitytransferase activity, transferring phosphorus-containing groupskinase activityprotein kinase activityprotein tyrosine kinase activitycyclin-dependent protein tyrosine kinase activityhistone tyrosine kinase activity +non-membrane spanning protein tyrosine kinase activityreceptor signaling protein tyrosine kinase activitytransmembrane receptor protein tyrosine kinase activity [GO:0004714] (61 genes, 124 annotations)boss receptor activitybrain-derived neurotrophic factor-activated receptor activityephrin receptor activity +epidermal growth factor-activated receptor activity +fibroblast growth factor-activated receptor activityhepatocyte growth factor-activated receptor activityinsulin-activated receptor activityinsulin-like growth factor-activated receptor activitymacrophage colony-stimulating factor receptor activityplacental growth factor-activated receptor activityplatelet-derived growth factor-activated receptor activity +protein tyrosine kinase collagen receptor activitystem cell factor receptor activityvascular endothelial growth factor-activated receptor activity +molecular_functioncatalytic activitytransferase activitytransferase activity, transferring phosphorus-containing groupskinase activityprotein kinase activitytransmembrane receptor protein kinase activitytransmembrane receptor histidine kinase activity +transmembrane receptor protein serine/threonine kinase activity +transmembrane receptor protein tyrosine kinase activity [GO:0004714] (61 genes, 124 annotations)boss receptor activitybrain-derived neurotrophic factor-activated receptor activityephrin receptor activity +epidermal growth factor-activated receptor activity +fibroblast growth factor-activated receptor activityhepatocyte growth factor-activated receptor activityinsulin-activated receptor activityinsulin-like growth factor-activated receptor activitymacrophage colony-stimulating factor receptor activityplacental growth factor-activated receptor activityplatelet-derived growth factor-activated receptor activity +protein tyrosine kinase collagen receptor activitystem cell factor receptor activityvascular endothelial growth factor-activated receptor activity +molecular_functioncatalytic activitytransferase activitytransferase activity, transferring phosphorus-containing groupsphosphotransferase activity, alcohol group as acceptorprotein kinase activityprotein tyrosine kinase activitycyclin-dependent protein tyrosine kinase activityhistone tyrosine kinase activity +non-membrane spanning protein tyrosine kinase activityreceptor signaling protein tyrosine kinase activitytransmembrane receptor protein tyrosine kinase activity [GO:0004714] (61 genes, 124 annotations)boss receptor activitybrain-derived neurotrophic factor-activated receptor activityephrin receptor activity +epidermal growth factor-activated receptor activity +fibroblast growth factor-activated receptor activityhepatocyte growth factor-activated receptor activityinsulin-activated receptor activityinsulin-like growth factor-activated receptor activitymacrophage colony-stimulating factor receptor activityplacental growth factor-activated receptor activityplatelet-derived growth factor-activated receptor activity +protein tyrosine kinase collagen receptor activitystem cell factor receptor activityvascular endothelial growth factor-activated receptor activity +molecular_functioncatalytic activitytransferase activitytransferase activity, transferring phosphorus-containing groupsphosphotransferase activity, alcohol group as acceptorprotein kinase activitytransmembrane receptor protein kinase activitytransmembrane receptor histidine kinase activity +transmembrane receptor protein serine/threonine kinase activity +transmembrane receptor protein tyrosine kinase activity [GO:0004714] (61 genes, 124 annotations)boss receptor activitybrain-derived neurotrophic factor-activated receptor activityephrin receptor activity +epidermal growth factor-activated receptor activity +fibroblast growth factor-activated receptor activityhepatocyte growth factor-activated receptor activityinsulin-activated receptor activityinsulin-like growth factor-activated receptor activitymacrophage colony-stimulating factor receptor activityplacental growth factor-activated receptor activityplatelet-derived growth factor-activated receptor activity +protein tyrosine kinase collagen receptor activitystem cell factor receptor activityvascular endothelial growth factor-activated receptor activity +molecular_functionmolecular transducer activitysignal transducer activitysignaling receptor activitytransmembrane signaling receptor activitytransmembrane receptor protein kinase activitytransmembrane receptor histidine kinase activity +transmembrane receptor protein serine/threonine kinase activity +transmembrane receptor protein tyrosine kinase activity [GO:0004714] (61 genes, 124 annotations)boss receptor activitybrain-derived neurotrophic factor-activated receptor activityephrin receptor activity +epidermal growth factor-activated receptor activity +fibroblast growth factor-activated receptor activityhepatocyte growth factor-activated receptor activityinsulin-activated receptor activityinsulin-like growth factor-activated receptor activitymacrophage colony-stimulating factor receptor activityplacental growth factor-activated receptor activityplatelet-derived growth factor-activated receptor activity +protein tyrosine kinase collagen receptor activitystem cell factor receptor activityvascular endothelial growth factor-activated receptor activity +molecular_functionreceptor activitysignaling receptor activitytransmembrane signaling receptor activitytransmembrane receptor protein kinase activitytransmembrane receptor histidine kinase activity +transmembrane receptor protein serine/threonine kinase activity +transmembrane receptor protein tyrosine kinase activity [GO:0004714] (61 genes, 124 annotations)boss receptor activitybrain-derived neurotrophic factor-activated receptor activityephrin receptor activity +epidermal growth factor-activated receptor activity +fibroblast growth factor-activated receptor activityhepatocyte growth factor-activated receptor activityinsulin-activated receptor activityinsulin-like growth factor-activated receptor activitymacrophage colony-stimulating factor receptor activityplacental growth factor-activated receptor activityplatelet-derived growth factor-activated receptor activity +protein tyrosine kinase collagen receptor activitystem cell factor receptor activityvascular endothelial growth factor-activated receptor activity +Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc |
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last database update 05/08/2013 MGI 5.13 |
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