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Gene Ontology Browser
Term Detail
GO term:transmembrane receptor protein serine/threonine kinase activity
Synonym: activin receptor kinase activity
Synonym: ATP:receptor-protein phosphotransferase activity
Synonym: receptor protein serine/threonine kinase activity
Synonym: receptor serine/threonine protein kinase activity
Synonym: receptor type II serine/threonine protein kinase activity
Synonym: receptor type I serine/threonine protein kinase activity
Synonym: STK13
Synonym: TGF-beta kinase activity
GO id:GO:0004675
Definition:Combining with a signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
Number of paths to term: 6

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-amolecular_function
                is-acatalytic activity
                        is-atransferase activity
                                is-atransferase activity, transferring phosphorus-containing groups
                                        is-akinase activity
                                                is-aprotein kinase activity
                                                        is-aprotein serine/threonine kinase activity
                                                                is-a3-phosphoinositide-dependent protein kinase activity
                                                                is-aAMP-activated protein kinase activity
                                                                is-acalcium-dependent protein serine/threonine kinase activity +
                                                                is-acalmodulin-dependent protein kinase activity +
                                                                is-acyclic nucleotide-dependent protein kinase activity +
                                                                is-acyclin-dependent protein serine/threonine kinase activity
                                                                is-aDNA-dependent protein kinase activity
                                                                is-aeukaryotic translation initiation factor 2alpha kinase activity
                                                                is-aFas-activated serine/threonine kinase activity
                                                                is-aG-protein coupled receptor kinase activity
                                                                is-aGoodpasture-antigen-binding protein kinase activity
                                                                is-aGTP-dependent protein kinase activity
                                                                is-ahistone serine kinase activity +
                                                                is-ahistone threonine kinase activity +
                                                                is-aIkappaB kinase activity
                                                                is-amyosin light chain kinase activity
                                                                is-aprotein kinase C activity +
                                                                is-areceptor signaling protein serine/threonine kinase activity +
                                                                is-aRho-dependent protein serine/threonine kinase activity
                                                                is-aribosomal protein S6 kinase activity
                                                                is-aRNA polymerase II carboxy-terminal domain kinase activity
                                                                is-atransmembrane receptor protein serine/threonine kinase activity [GO:0004675] (22 genes, 57 annotations)
                                                                        is-aactivin-activated receptor activity +
                                                                        is-atransforming growth factor beta-activated receptor activity +


Gene_Ontology
        is-amolecular_function
                is-acatalytic activity
                        is-atransferase activity
                                is-atransferase activity, transferring phosphorus-containing groups
                                        is-akinase activity
                                                is-aprotein kinase activity
                                                        is-atransmembrane receptor protein kinase activity
                                                                is-atransmembrane receptor histidine kinase activity +
                                                                is-atransmembrane receptor protein serine/threonine kinase activity [GO:0004675] (22 genes, 57 annotations)
                                                                        is-aactivin-activated receptor activity +
                                                                        is-atransforming growth factor beta-activated receptor activity +
                                                                is-atransmembrane receptor protein tyrosine kinase activity +


Gene_Ontology
        is-amolecular_function
                is-acatalytic activity
                        is-atransferase activity
                                is-atransferase activity, transferring phosphorus-containing groups
                                        is-aphosphotransferase activity, alcohol group as acceptor
                                                is-aprotein kinase activity
                                                        is-aprotein serine/threonine kinase activity
                                                                is-a3-phosphoinositide-dependent protein kinase activity
                                                                is-aAMP-activated protein kinase activity
                                                                is-acalcium-dependent protein serine/threonine kinase activity +
                                                                is-acalmodulin-dependent protein kinase activity +
                                                                is-acyclic nucleotide-dependent protein kinase activity +
                                                                is-acyclin-dependent protein serine/threonine kinase activity
                                                                is-aDNA-dependent protein kinase activity
                                                                is-aeukaryotic translation initiation factor 2alpha kinase activity
                                                                is-aFas-activated serine/threonine kinase activity
                                                                is-aG-protein coupled receptor kinase activity
                                                                is-aGoodpasture-antigen-binding protein kinase activity
                                                                is-aGTP-dependent protein kinase activity
                                                                is-ahistone serine kinase activity +
                                                                is-ahistone threonine kinase activity +
                                                                is-aIkappaB kinase activity
                                                                is-amyosin light chain kinase activity
                                                                is-aprotein kinase C activity +
                                                                is-areceptor signaling protein serine/threonine kinase activity +
                                                                is-aRho-dependent protein serine/threonine kinase activity
                                                                is-aribosomal protein S6 kinase activity
                                                                is-aRNA polymerase II carboxy-terminal domain kinase activity
                                                                is-atransmembrane receptor protein serine/threonine kinase activity [GO:0004675] (22 genes, 57 annotations)
                                                                        is-aactivin-activated receptor activity +
                                                                        is-atransforming growth factor beta-activated receptor activity +


Gene_Ontology
        is-amolecular_function
                is-acatalytic activity
                        is-atransferase activity
                                is-atransferase activity, transferring phosphorus-containing groups
                                        is-aphosphotransferase activity, alcohol group as acceptor
                                                is-aprotein kinase activity
                                                        is-atransmembrane receptor protein kinase activity
                                                                is-atransmembrane receptor histidine kinase activity +
                                                                is-atransmembrane receptor protein serine/threonine kinase activity [GO:0004675] (22 genes, 57 annotations)
                                                                        is-aactivin-activated receptor activity +
                                                                        is-atransforming growth factor beta-activated receptor activity +
                                                                is-atransmembrane receptor protein tyrosine kinase activity +


Gene_Ontology
        is-amolecular_function
                is-amolecular transducer activity
                        is-asignal transducer activity
                                is-asignaling receptor activity
                                        is-atransmembrane signaling receptor activity
                                                is-atransmembrane receptor protein kinase activity
                                                        is-atransmembrane receptor histidine kinase activity +
                                                        is-atransmembrane receptor protein serine/threonine kinase activity [GO:0004675] (22 genes, 57 annotations)
                                                                is-aactivin-activated receptor activity +
                                                                is-atransforming growth factor beta-activated receptor activity +
                                                        is-atransmembrane receptor protein tyrosine kinase activity +


Gene_Ontology
        is-amolecular_function
                is-areceptor activity
                        is-asignaling receptor activity
                                is-atransmembrane signaling receptor activity
                                        is-atransmembrane receptor protein kinase activity
                                                is-atransmembrane receptor histidine kinase activity +
                                                is-atransmembrane receptor protein serine/threonine kinase activity [GO:0004675] (22 genes, 57 annotations)
                                                        is-aactivin-activated receptor activity +
                                                        is-atransforming growth factor beta-activated receptor activity +
                                                is-atransmembrane receptor protein tyrosine kinase activity +


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory