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Term Detail
GO term:phosphoribosylamine-glycine ligase activity
Synonym: 2-amino-N-ribosylacetamide 5'-phosphate kinosynthase activity
Synonym: 5-phospho-D-ribosylamine:glycine ligase (ADP-forming)
Synonym: 5'-phosphoribosylglycinamide synthetase activity
Synonym: GAR
Synonym: GARS activity
Synonym: GAR synthetase activity
Synonym: glycinamide ribonucleotide synthetase activity
Synonym: glycineamide ribonucleotide synthetase activity
Synonym: phosphoribosylglycinamide synthetase activity
Synonym: phosphoribosylglycineamide synthetase activity
GO id:GO:0004637
Definition:Catalysis of the reaction: 5-phospho-D-ribosylamine + ATP + glycine = N(1)-(5-phospho-D-ribosyl)glycinamide + ADP + 2 H(+) + phosphate.
Number of paths to term: 1

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-amolecular_function
                is-acatalytic activity
                        is-aligase activity
                                is-aligase activity, forming carbon-nitrogen bonds
                                        is-a5-(carboxyamino)imidazole ribonucleotide synthase activity
                                        is-aacid-amino acid ligase activity +
                                        is-aacid-ammonia (or amide) ligase activity +
                                        is-aadenylosuccinate synthase activity
                                        is-aargininosuccinate synthase activity
                                        is-aAtg8 ligase activity
                                        is-abiotin carboxylase activity
                                        is-abiotin-protein ligase activity +
                                        is-acarbamoyl-phosphate synthase (ammonia) activity
                                        is-acarbon-nitrogen ligase activity, with glutamine as amido-N-donor +
                                        is-acitrate-L-glutamate ligase activity
                                        is-aCTP synthase activity
                                        is-acyclo-ligase activity +
                                        is-aformate-dihydrofolate ligase activity
                                        is-aformate-tetrahydrofolate ligase activity
                                        is-aglutamate-methylamine ligase activity
                                        is-aGMP synthase activity
                                        is-aimidazoleacetate-phosphoribosyldiphosphate ligase activity
                                        is-alipoate-protein ligase activity +
                                        is-aN-acetyl-L-aspartate-L-glutamate ligase activity
                                        is-aphosphoribosylamine-glycine ligase activity [GO:0004637] (2 genes, 2 annotations)
                                        is-aribose-5-phosphate-ammonia ligase activity
                                        is-asulfinylpropanyl adenylate synthase
                                        is-atRNA(Ile)-lysidine synthase activity
                                        is-aurea carboxylase activity


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory