| GO term: | tryptophan 5-monooxygenase activity |
| Synonym: | indoleacetic acid-5-hydroxylase activity |
| Synonym: | L-tryptophan hydroxylase activity |
| Synonym: | L-tryptophan,tetrahydrobiopterin:oxygen oxidoreductase (5-hydroxylating) |
| Synonym: | tryptophan 5-hydroxylase activity |
| Synonym: | tryptophan hydroxylase activity |
| GO id: | GO:0004510 |
| Definition: | Catalysis of the reaction: L-tryptophan + tetrahydrobiopterin + O2 = 5-hydroxy-L-tryptophan + 4-alpha-hydroxytetrahydrobiopterin + H2O. |
| Number of paths to term: | 2 |
denotes an 'is-a' relationship
denotes a 'part-of' relationship
denotes a 'regulates' relationship
denotes a 'positively-regulates' relationship
denotes a 'negatively-regulates' relationship
molecular_functioncatalytic activityoxidoreductase activitymonooxygenase activityoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygenanthranilate 3-monooxygenase activityglyceryl-ether monooxygenase activitymandelate 4-monooxygenase activityphenylalanine 4-monooxygenase activitytryptophan 5-monooxygenase activity [GO:0004510] (2 genes, 3 annotations)tyrosine 3-monooxygenase activitymolecular_functioncatalytic activityoxidoreductase activityoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygenoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygenanthranilate 3-monooxygenase activityglyceryl-ether monooxygenase activitymandelate 4-monooxygenase activityphenylalanine 4-monooxygenase activitytryptophan 5-monooxygenase activity [GO:0004510] (2 genes, 3 annotations)tyrosine 3-monooxygenase activityMouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc |
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last database update 06/05/2013 MGI 5.13 |
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