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Gene Ontology Browser
Term Detail
GO term:tryptophan 5-monooxygenase activity
Synonym: indoleacetic acid-5-hydroxylase activity
Synonym: L-tryptophan hydroxylase activity
Synonym: L-tryptophan,tetrahydrobiopterin:oxygen oxidoreductase (5-hydroxylating)
Synonym: tryptophan 5-hydroxylase activity
Synonym: tryptophan hydroxylase activity
GO id:GO:0004510
Definition:Catalysis of the reaction: L-tryptophan + tetrahydrobiopterin + O2 = 5-hydroxy-L-tryptophan + 4-alpha-hydroxytetrahydrobiopterin + H2O.
Number of paths to term: 2

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-amolecular_function
                is-acatalytic activity
                        is-aoxidoreductase activity
                                is-amonooxygenase activity
                                        is-aoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen
                                                is-aanthranilate 3-monooxygenase activity
                                                is-aglyceryl-ether monooxygenase activity
                                                is-amandelate 4-monooxygenase activity
                                                is-aphenylalanine 4-monooxygenase activity
                                                is-atryptophan 5-monooxygenase activity [GO:0004510] (2 genes, 3 annotations)
                                                is-atyrosine 3-monooxygenase activity


Gene_Ontology
        is-amolecular_function
                is-acatalytic activity
                        is-aoxidoreductase activity
                                is-aoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
                                        is-aoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen
                                                is-aanthranilate 3-monooxygenase activity
                                                is-aglyceryl-ether monooxygenase activity
                                                is-amandelate 4-monooxygenase activity
                                                is-aphenylalanine 4-monooxygenase activity
                                                is-atryptophan 5-monooxygenase activity [GO:0004510] (2 genes, 3 annotations)
                                                is-atyrosine 3-monooxygenase activity


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/26/2014
MGI 5.19
The Jackson Laboratory