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Term Detail
GO term:monophenol monooxygenase activity
Synonym: catecholase
Synonym: chlorogenic acid oxidase activity
Synonym: chlorogenic oxidase activity
Synonym: cresolase activity
Synonym: dopa oxidase
Synonym: L-tyrosine monooxygenase activity
Synonym: monophenolase activity
Synonym: monophenol, dihydroxy-L-phenylalanine oxygen oxidoreductase activity
Synonym: monophenol dihydroxyphenylalanine:oxygen oxidoreductase activity
Synonym: monophenol,L-dopa:oxygen oxidoreductase activity
Synonym: monophenol monooxidase activity
Synonym: monophenol oxidase activity
Synonym: monophenol oxygenase
Synonym: N-acetyl-6-hydroxytryptophan oxidase activity
Synonym: o-diphenol:O2 oxidoreductase activity
Synonym: o-diphenol oxidase activity
Synonym: o-diphenol oxidoreductase
Synonym: o-diphenol:oxygen oxidoreductase
Synonym: phenolase activity
Synonym: phenol oxidase activity
Synonym: polyaromatic oxidase activity
Synonym: polyphenolase activity
Synonym: prophenol oxidase activity
Synonym: prophenoloxidase activity
Synonym: pyrocatechol oxidase
Synonym: tyrosinase activity
Synonym: tyrosine-dopa oxidase activity
GO id:GO:0004503
Definition:Catalysis of the reaction: L-tyrosine + L-DOPA + O2 = L-DOPA + DOPAquinone + H2O.
CommentsIn mammals, L-DOPA can act as a cofactor for the catalyzed reaction; therefore in some resources L-DOPA is shown on both sides of the reaction. GO:0004503 describes the monooxygenation of the monophenol, L-tyrosine. For oxidation of diphenols (including L-DOPA and dopamine), consider instead the term 'catechol oxidase activity ; GO:0004097' and its children.
Number of paths to term: 2

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-amolecular_function
                is-acatalytic activity
                        is-aoxidoreductase activity
                                is-amonooxygenase activity
                                        is-aoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen
                                                is-a6-hydroxy pseudo-oxynicotine monooxygenase activity
                                                is-aCMP-N-acetylneuraminate monooxygenase activity
                                                is-amonophenol monooxygenase activity [GO:0004503] (1 genes, 2 annotations)


Gene_Ontology
        is-amolecular_function
                is-acatalytic activity
                        is-aoxidoreductase activity
                                is-aoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
                                        is-aoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen
                                                is-a6-hydroxy pseudo-oxynicotine monooxygenase activity
                                                is-aCMP-N-acetylneuraminate monooxygenase activity
                                                is-amonophenol monooxygenase activity [GO:0004503] (1 genes, 2 annotations)


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory