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Gene Ontology Browser
Term Detail
GO term:helicase activity
GO id:GO:0004386
Definition:Catalysis of the reaction: NTP + H2O = NDP + phosphate, to drive the unwinding of a DNA or RNA helix.
CommentsNote that most helicases catalyze processive duplex unwinding.
Number of paths to term: 1

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-amolecular_function
                is-acatalytic activity
                        is-ahydrolase activity
                                is-ahydrolase activity, acting on acid anhydrides
                                        is-ahydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
                                                is-apyrophosphatase activity
                                                        is-anucleoside-triphosphatase activity
                                                                is-aannealing helicase activity
                                                                is-aATPase activity +
                                                                is-aCTPase activity
                                                                is-aGTPase activity +
                                                                is-ahelicase activity [GO:0004386] (151 genes, 267 annotations)
                                                                        is-aDNA helicase activity +
                                                                        is-aDNA/RNA helicase activity +
                                                                        is-apurine NTP-dependent helicase activity +
                                                                        is-aRNA helicase activity +
                                                                is-amotor activity +
                                                                is-athiamin-triphosphatase activity
                                                                is-athymidine-triphosphatase activity


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory