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Gene Ontology Browser
Term Detail
GO term:peptidyl-prolyl cis-trans isomerase activity
Synonym: cis-trans proline isomerase activity
Synonym: cyclophilin activity
Synonym: cyclophilin-type peptidyl-prolyl cis-trans isomerase activity
Synonym: FK506-sensitive peptidyl-prolyl cis-trans isomerase
Synonym: immunophilin
Synonym: juglone-sensitive cis-trans proline isomerase activity
Synonym: juglone-sensitive peptidyl-prolyl cis-trans isomerase activity
Synonym: parvulin
Synonym: peptide bond isomerase activity
Synonym: peptidylproline cis-trans-isomerase activity
Synonym: peptidylprolyl cis-trans isomerase activity
Synonym: peptidylprolyl isomerase activity
Synonym: peptidyl-prolyl isomerase B reaction
Synonym: PPIase activity
Synonym: rotamase activity
GO id:GO:0003755
Definition:Catalysis of the reaction: peptidyl-proline (omega=180) = peptidyl-proline (omega=0).
Number of paths to term: 1

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-amolecular_function
                is-acatalytic activity
                        is-aisomerase activity
                                is-acis-trans isomerase activity
                                        is-a2-chloro-4-carboxymethylenebut-2-en-1,4-olide isomerase activity
                                        is-a4-hydroxyphenylacetaldehyde-oxime isomerase activity
                                        is-a9,15,9'-tri-cis-zeta-carotene isomerase activity
                                        is-acarotenoid isomerase activity
                                        is-acis-4-[2-(3-hydroxy)-thionaphthenyl]-2-oxo-3-butenoate isomerase activity
                                        is-afarnesol 2-isomerase activity
                                        is-afurylfuramide isomerase activity
                                        is-alinoleate isomerase activity
                                        is-amaleate isomerase activity
                                        is-amaleylacetoacetate isomerase activity
                                        is-amaleylpyruvate isomerase activity
                                        is-apeptidyl-prolyl cis-trans isomerase activity [GO:0003755] (39 genes, 45 annotations)
                                        is-aretinal isomerase activity
                                        is-aretinol isomerase activity
                                        is-atrans-geranyl-CoA isomerase activity


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory