| GO term: | antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent |
| Synonym: | endogenous peptide antigen processing and presentation via MHC class I via ER pathway, TAP-dependent |
| Synonym: | TAP-dependent antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway |
| Synonym: | TAP-dependent endogenous peptide antigen processing and presentation via MHC class I via ER pathway |
| GO id: | GO:0002485 |
| Definition: | The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via a TAP-dependent ER pathway. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and becomes associated with the MHC class I molecule in the ER following TAP-dependent transport from the cytosol. Class I here refers to classical class I molecules. |
| Number of paths to term: | 3 |
denotes an 'is-a' relationship
denotes a 'part-of' relationship
denotes a 'regulates' relationship
denotes a 'positively-regulates' relationship
denotes a 'negatively-regulates' relationship
biological_processimmune system processantigen processing and presentationantigen processing and presentation of endogenous antigenantigen processing and presentation of endogenous peptide antigenantigen processing and presentation of endogenous peptide antigen via MHC class Iantigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathwayantigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485] (3 genes, 3 annotations)antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independentbiological_processimmune system processantigen processing and presentationantigen processing and presentation of peptide antigenantigen processing and presentation of endogenous peptide antigenantigen processing and presentation of endogenous peptide antigen via MHC class Iantigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathwayantigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485] (3 genes, 3 annotations)antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independentbiological_processimmune system processantigen processing and presentationantigen processing and presentation of peptide antigenantigen processing and presentation of peptide antigen via MHC class Iantigen processing and presentation of endogenous peptide antigen via MHC class Iantigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathwayantigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485] (3 genes, 3 annotations)antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independentMouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc |
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last database update 05/08/2013 MGI 5.13 |
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