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Gene Ontology Browser
Term Detail
GO term:antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent
Synonym: endogenous peptide antigen processing and presentation via MHC class I via ER pathway, TAP-dependent
Synonym: TAP-dependent antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway
Synonym: TAP-dependent endogenous peptide antigen processing and presentation via MHC class I via ER pathway
GO id:GO:0002485
Definition:The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via a TAP-dependent ER pathway. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and becomes associated with the MHC class I molecule in the ER following TAP-dependent transport from the cytosol. Class I here refers to classical class I molecules.
Number of paths to term: 3

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-abiological_process
                is-aimmune system process
                        is-aantigen processing and presentation
                                is-aantigen processing and presentation of endogenous antigen
                                        is-aantigen processing and presentation of endogenous peptide antigen
                                                is-aantigen processing and presentation of endogenous peptide antigen via MHC class I
                                                        is-aantigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway
                                                                is-aantigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485] (4 genes, 4 annotations)
                                                                is-aantigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent


Gene_Ontology
        is-abiological_process
                is-aimmune system process
                        is-aantigen processing and presentation
                                is-aantigen processing and presentation of peptide antigen
                                        is-aantigen processing and presentation of endogenous peptide antigen
                                                is-aantigen processing and presentation of endogenous peptide antigen via MHC class I
                                                        is-aantigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway
                                                                is-aantigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485] (4 genes, 4 annotations)
                                                                is-aantigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent


Gene_Ontology
        is-abiological_process
                is-aimmune system process
                        is-aantigen processing and presentation
                                is-aantigen processing and presentation of peptide antigen
                                        is-aantigen processing and presentation of peptide antigen via MHC class I
                                                is-aantigen processing and presentation of endogenous peptide antigen via MHC class I
                                                        is-aantigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway
                                                                is-aantigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485] (4 genes, 4 annotations)
                                                                is-aantigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory