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Myh6em2(cre)Smoc - Cardiovascular System
Recombinase Activity Detail
Allele Information
Allele:
Myh6em2(cre)Smoc
myosin, heavy polypeptide 6, cardiac muscle, alpha; endonuclease-mediated mutation 2, Shanghai Model Organisms Center 		Driver: Myh6
Type: Endonuclease-mediated (Recombinase)
Synonym: Myh6-Cre, Myh6em(Cre)1Smoc
Molecular description: The CRISPR/Cas9 technology was used to insert the internal ribosome entry site (IRES)-Cre cassette, the woodchuck hepatitis virus posttranscriptional regulatory element (wpre), and a polyA sequence between the translational stop codon and the 3' UTR of the endogenous Myh6 gene.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Additional Tissues: Myh6em2(cre)Smoc activity also observed in:
hemolymphoid system, liver & biliary system, muscle, renal & urinary system, respiratory system
Tissue Information
Cardiovascular System Other recombinase alleles with activity in Cardiovascular System tissues:
Images
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J:337240 Fig. 2 J:337240 Fig. 3 J:337240 Fig. 4 J:337240 Fig. S1
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory