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Tg(Nes-cre/ERT2,-EGFP,-HBEGF)1Lfp - Nervous System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Nes-cre/ERT2,-EGFP,-HBEGF)1Lfp
transgene insertion 1, Luis F Parada
Driver: Nes
Type: Transgenic (Epitope tag, Inducible, Inserted expressed sequence, Recombinase, Reporter)
Synonym: CGD
Molecular description: The 5.6 kb of the rat 5' regulatory element followed by CreERT2, histone 2B tagged enhanced GFP, and human diphtheria toxin receptor (CGD), each element separated by p2A sequences, and 668bp of the inverted second intron were used to express three proteins from one transcript in neural stem cells. Twenty-nine transgenic founder lines were identified. A single founder that displayed the specific expression pattern without detectable ectopic expression was established.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Additional Tissues: Tg(Nes-cre/ERT2,-EGFP,-HBEGF)1Lfp activity also observed in:
head
Tissue Information
Nervous System Other recombinase alleles with activity in Nervous System tissues:
Images
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J:299260 Fig. 1 J:299260 Fig. 6
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory