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Agrptm4.1(cre/EGFP)Rpa - Head
Recombinase Activity Detail
Allele Information
Allele:
Agrptm4.1(cre/EGFP)Rpa
agouti related neuropeptide; targeted mutation 4.1, Richard D Palmiter 		Driver: Agrp
Type: Targeted (Epitope tag, Recombinase, Reporter)
Synonym: AgrpCre:GFP(version 2)
Molecular description: The targeting construct introduced a cassette containing the following features, without the nuclear localization signal, using a nonoptimal initiation codon, a cre recombinase gene fused with EGFP (cre/EGFP) with N-term sequence removed, and a myc tag with an additional 3 untranslated region from the Myc gene that promotes a short messenger RNA half-life. Flp-mediated recombination removed the FRT-flanked neomycin resistance cassette introduced downstream of the fusion gene. It is a revised "version 2" of the allele Agrptm1.1(cre/EGFP)Stei designed to have an attenuated expression of Cre:GFP.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Additional Tissues: Agrptm4.1(cre/EGFP)Rpa activity also observed in:
nervous system
Tissue Information
Head Other recombinase alleles with activity in Head tissues:
Images
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J:295967 Fig. 1
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory