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Tg(Gata1-cre/ERT2)1Mym - Skeletal System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Gata1-cre/ERT2)1Mym
transgene insertion 1, Masayuki Yamamoto
Driver: Gata1
Type: Transgenic (Inducible, Recombinase)
Inducer: tamoxifen
Synonym: MG-CreERT2
Molecular description: The mouse BAC clone (RP23-443E19) containing the entire Gata1 locus is driven in hematopoietic cells by 659bp fragments consisting of the three regulatory elements of the Gata1 gene, G1HE, dbG, and CACCC elements combined mini-gene (MG). The expression cassette consisting of Cre/ERT2-polyA-Neo was inserted into the endogenous Gata1 initiating ATG by recombination. The correct clone was then used for Neo excision. Founder information and line numbers were not available. Two lines (Line 1 and 2) were established and used for the study.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Additional Tissues: Tg(Gata1-cre/ERT2)1Mym activity also observed in:
hemolymphoid system
Tissue Information
Skeletal System Other recombinase alleles with activity in Skeletal System tissues:
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory