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Tg(Asic1-cre)1Cibms - Nervous System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Asic1-cre)1Cibms
transgene insertion 1, Chih-Cheng Chen 		Driver: Asic1
Type: Transgenic (Recombinase)
Synonym: Asic1bCre, ASIC1b-Cre
Molecular description: The transgene consists of a ~4.5-kb mouse genomic DNA fragment containing the promoter upstream of the ATG translation start codon of a splicing variant of Asic1, ASIC1b to drive the Cre recombinase expression. The whole ASIC1b-CreDNA cassette was flanked by the chicken hypersensitive site 4 (HS4) insulator. Five founder mice were retained for copy number verification and two founder lines bearing a minimum copy transgene were screened. One of the five founder mice showing expression of Cre only in the trigeminal ganglia and DRG but not the brain was used for the study.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Tissue Information
Nervous System Other recombinase alleles with activity in Nervous System tissues:
Images
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J:309655 Fig. 3
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory