Cpne7<tm1.1(cre)Sleep> - Head Recombinase Activity Detail MGI Mouse

Cpne7^{tm1.1(cre)Sleep} - Head
Recombinase Activity Detail

Allele Information | Tissue Information | Recombinase Activity | References

Allele Information

Allele:

Cpne7^{tm1.1(cre)Sleep}
copine VII; targeted mutation 1.1, Yu Hayashi

Driver: Cpne7
Type: Targeted (Null/knockout, Recombinase)

Synonym:

Cpne7^Cre, Cpne7-KO

Molecular description:

Via homologous recombination in ES cells, the targeting vector inserted a nuclear localization sequence(NLS)-Cre-FRT-PGK-gb2-neo-FRT cassette (Cre cassette) downstream of the Cpne7 promoter. The PGK-Neo cassette was removed by crossing mice with CAG-FLPe mice. The western blot of whole brain samples did not show the detectable level of Cpne7 protein in homozygous mice. It is a null allele.

Find mice (IMSR):

Mouse Strains: 0 strains available Cell Lines: 0 lines available

Additional Tissues:

Cpne7^{tm1.1(cre)Sleep} activity also observed in:
nervous system

Tissue Information

Head

Other recombinase alleles with activity in Head tissues:

7630403G23Rik^{Tg(Th-cre)1Tmd}, Abcg2^{tm1.1(cre/Esr1*)Jvbe}, Acan^{tm1(cre/ERT2)Crm}, Acsm4^tm1(cre)Hsak ...(more)

Recombinase Activity

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Assays Genotypic Background Result Notes

References

All for this allele:

1 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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