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Allele Information
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Allele:
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Il17atm2.1(EGFP/cre/ERT2)Flv
interleukin 17A;
targeted mutation 2.1, Richard A Flavell
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Driver: Il17a
Type: Targeted
(Inducible, Recombinase, Reporter)
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Inducer:
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tamoxifen
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Synonym:
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IL-17A IRES-eGFP-CRE-ERT2
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Molecular description:
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A cassette encoding for a fusion protein consisting of the Internal Ribosome Entry Site (IRES), eGFP, Cre and human-modified Oestrogen Receptor (ERT2) (IGCE) was linked to a Frt-flanked neomycin (NEO) encoding cassette and inserted downstream of the translation stop codon in the mouse Il17a gene by targetted homologous recombination in ES cells. Germline transmitted mice were bred with germline Flippase expressing transgenic mice to remove the neomycin gene.
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Find mice (IMSR):
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Mouse Strains:
0 strains available
Cell Lines:
0 lines available
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Additional Tissues:
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Il17atm2.1(EGFP/cre/ERT2)Flv activity also observed in:
alimentary system
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Tissue Information
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Mouse-other
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Other recombinase alleles with activity in Mouse-other tissues:
Acantm1(cre/ERT2)Crm,
Alpltm1(cre)Nagy,
Amhr2em1(icre)Fjd,
Amhr2tm3(cre)Bhr,
Cd19em1.1(icre)Yoba,
Cdkn2atm1.1(cre)Dvb,
Clec9atm2.1(icre)Crs,
Cx3cr1tm1.1(cre)Jung,
Cx3cr1tm2.1(cre/ERT2)Jung,
Cxcr4tm1.1(cre/ERT2)Stum,
Dmp1tm1(cre)Msue,
Epxtm1.1(cre)Jlee,
Esrrbtm1(cre)Yba,
Fcgr1em1.1(cre)Moli,
Foxa2tm3.1(icre)Heli,
Foxp3tm4(EGFP/icre)Tch,
Foxp3tm4(YFP/icre)Ayr,
Ghem1(cre)Jmz,
Gt(ROSA)26Sorem1(CAG-Ncre/vvd*,-vvd*/Ccre)Larc,
Gt(ROSA)26Sortm13(dreo)Maoh,
Gt(ROSA)26Sortm3(CAG-Vcre)Maito,
Gt(ROSA)26Sortm4(CAG-Scre)Maito,
Hoxa11em1(cre/ERT2)Dmwe,
Hprt1tm1(CAG-cre)Mnn,
Hsd11b2tm1(cre)Anft,
Igs2tm1(Cdkn1a-cre/ERT2,-EGFP)Mxu,
Krt17tm1(cre)Murr,
Lhx1tm1.1(icre)Rob,
Ly6gtm2621(cre)Arte,
Mecomem1(cre/ERT2)Suda,
Ms4a3em2(cre)Fgnx,
Ms4a3tm1(cre/ERT2)Smoc,
Nkx1-2tm2296.1(cre/ERT2)Arte,
Notch1tm3(cre)Rko,
Nox3tm1.1(cre)Kobio,
Prdm1tm3(icre)Rob,
Prdm1tm5.1(cre/ERT2)Rob,
Rbpmsem1(cre/ERT2)Yzhe,
Runx1tm1(cre/Esr1*)Ims,
Scxtm1.1(cre)Shuk,
Scxtm2.1(cre/ERT2)Stzr,
Sox17tm1(icre)Heli,
Sox17tm2.1(icre)Heli,
Tbx21tm1.1(cre/ERT2)Ayr,
Tbx21tm1.1(cre)Gmld,
Tg(Acan-cre/ERT2,-luc)1Gbg,
Tg(Acp5-cre)3Rda,
Tg(Acp5-cre)4Rda,
Tg(Acta2-cre/ERT2)1Ikal,
Tg(ACTB-cre)#Bzsh,
Tg(Acvrl1-cre)B1Spo,
Tg(Acvrl1-cre)L1Spo,
Tg(Aicda-cre,-CD2)1Hon,
Tg(Aicda-cre,-CD2)dME1Hon,
Tg(Bglap2-cre)2Kry,
Tg(CAG-cre)2Osb,
Tg(Cd4-cre)1Cwi,
Tg(Cd74-cre)#Tfk,
Tg(Cdh5-cre)1Spe,
Tg(CDX2-cre)101Erf,
Tg(Cer1-cre/ERT2)1Hmd,
Tg(Col10a1-cre)1427Vdm,
Tg(Col10a1-cre)1Xya,
Tg(Col11a2-cre)4Nhzi,
Tg(Col1a1-cre)1Bek,
Tg(Col1a1-cre)2Bek,
Tg(Col1a2-cre/ERT,-ALPP)7Cpd,
Tg(Col2a1-cre)1Bhr,
Tg(Col2a1-cre)1Star,
Tg(Col2a1-cre)1Xya,
Tg(Col2a1-cre/ERT)1Flng,
Tg(Col2a1-cre/ERT2)1Dic,
Tg(Col2a1-cre/ERT)KA3Smac,
Tg(Csrp1-cre)1Sjc,
Tg(EIIa-cre)C5379Lmgd,
Tg(Eno2-cre)39Jme,
Tg(Epx-EYFP/cre)#Voeh,
Tg(Flt3-cre)#Ccb,
Tg(Flt3-cre/ERT2)#Ccb,
Tg(Gdf5-cre,-ALPP)1Kng,
Tg(Hoxb8-dre)#Uze,
Tg(KRT14-cre)1Efu,
Tg(Lck-cre)1Cwi,
Tg(Lefty1-cre)2Hmd,
Tg(Lefty1-cre/ERT2)8Hmd,
Tg(Mcpt8-icre/ERT2)#Hkar,
Tg(Nanog-cre/Esr1*)4470Mms,
Tg(Ncr1-cre/ERT2)#Lll,
Tg(Pdgfb-icre/ERT2,-EGFP)1Frut,
Tg(Postn-cre/ERT2)#Fcko,
Tg(Prdm1-cre)1Masu,
Tg(Prg4-cre/ERT2)#Ndy,
Tg(Retnla-cre)#Voeh,
Tg(Rorc-cre)1Litt,
Tg(rtetR-tetO-cre)40Mhz,
Tg(Runx1/Hspa1a-cre/ERT2)#Itoy,
Tg(Runx2-icre)1Jtuc,
Tg(S100a4-flpo)3Lba,
Tg(Scx-cre)HShuk,
Tg(Scx-cre)LShuk,
Tg(Sp7-tTA,tetO-EGFP/cre)1Amc,
Tg(Tagln-cre)1Jjl,
Tg(Tagln-cre)1Jomm,
Tg(Tbx6-cre)#Rsam,
Tg(Tek-cre)12Flv,
Tg(Tek-cre)1Ywa,
Tg(TSPY1-cre)33aYfcl,
Tg(Wnt11-cre/ERT2)1Jwng,
Tigitem1(cre/ERT2)Tebi,
Tnfsf11em2(cre)Htaka,
Tppp3tm1.1(icre/ERT2)Fan,
Tppp3tm2.1(cre/ERT2)Fan,
Twist2tm1.1(cre)Dor,
Twist2tm1(cre)Dor,
Zfp683tm1.1(cre,Hbegf)Kgis
(less)
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Recombinase Activity
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References
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Analysis Tools