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Tg(VIPR2/Hspa1b-cre/ERT2)1Dlee - Alimentary System
Recombinase Activity Detail
Allele Information
Allele:
Tg(VIPR2/Hspa1b-cre/ERT2)1Dlee
transgene insertion 1, Daekee Lee 		Driver: VIPR2
Type: Transgenic (Inducible, Recombinase)
Inducer: tamoxifen
Synonym: VIPR2-ERT2CreERT2-001
Molecular description: A transgene consisting of hs1753 (chr7:158,888,320-158,891,362) enhancer element located in intron 4 of human VIPR2 gene subcloned into Hsp68 promoter fused with ERT2CreERT2-pA to drive expression of cre in response to tamoxifen in developing heart. A total of nine transgenic founders lines 1, 17, 20, 22, 23, 29, 30, 32, 33 were obtained. All transgenic lines showed heart-specific cre activity when bred to a cre reporter mouse. Transgenic line 001 exhibited the strongest expression of the reporter gene and was used for further studies.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Additional Tissues: Tg(VIPR2/Hspa1b-cre/ERT2)1Dlee activity also observed in:
cardiovascular system
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory