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Tg(Runx1/Hspa1a-cre/ERT2)5-2Itoy - Alimentary System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Runx1/Hspa1a-cre/ERT2)5-2Itoy
transgene insertion 5-2, Yoshiaki Ito 		Driver: Runx1
Type: Transgenic (Inducible, Recombinase)
Inducer: tamoxifen
Synonym: eR1-CreERT2(5-2)
Molecular description: The transgenic construct contains mouse Runx1 enhancer element sequence (eR1) and the mouse Hspa1a (heat-shock protein 68) basal promoter sequence driving the expression of cre/ERT2. More than 10 founder lines were generated. The line TG(5-2) with higher copy number and TG(3-7) with lower copy number used for studies. Although the former had higher Cre recombinase activity than the latter, the results obtained using these lines were qualitatively indistinguishable.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Additional Tissues: Tg(Runx1/Hspa1a-cre/ERT2)5-2Itoy activity also observed in:
hemolymphoid system
Tissue Information
Alimentary System Other recombinase alleles with activity in Alimentary System tissues:
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 3 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory