Ndnf<tm1.1(cre/ERT2)Ispgl> - Head Recombinase Activity Detail MGI Mouse

Ndnf^{tm1.1(cre/ERT2)Ispgl} - Head
Recombinase Activity Detail

Allele Information | Tissue Information | Recombinase Activity | References

Allele Information

Allele:

Ndnf^{tm1.1(cre/ERT2)Ispgl}
neuron-derived neurotrophic factor; targeted mutation 1.1, Ivo Spiegel

Driver: Ndnf
Type: Targeted (Inducible, Recombinase)

Inducer:

tamoxifen

Synonym:

Ndnf-IRES-CreERT2

Molecular description:

The targeting vector was designed to insert an internal ribosome entry site (IRES) fused to a Cre/ERT2 fusion gene (Cre recombinase fused to a human estrogen receptor ligand binding domain) into the 3' UTR in exon 4 of the neuron-derived neurotrophic factor (Ndnf) gene. The construct also included a frt-flanked neomycin resistance cassette. After homologouse recombination in ES cells, the resulting chimeric mice were bred with flp recombinase expressing mice to remove the neo cassette.

Find mice (IMSR):

Mouse Strains: 1 strain available Cell Lines: 0 lines available

Additional Tissues:

Ndnf^{tm1.1(cre/ERT2)Ispgl} activity also observed in:
nervous system

Tissue Information

Head

Other recombinase alleles with activity in Head tissues:

7630403G23Rik^{Tg(Th-cre)1Tmd}, Abcg2^{tm1.1(cre/Esr1*)Jvbe}, Acan^{tm1(cre/ERT2)Crm}, Acsm4^tm1(cre)Hsak ...(more)

Recombinase Activity

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Assays Genotypic Background Result Notes

References

All for this allele:

2 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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