Slc17a8<em1(icre/ERT2)Zyliu> - Head Recombinase Activity Detail MGI Mouse

Slc17a8^{em1(icre/ERT2)Zyliu} - Head
Recombinase Activity Detail

Allele Information | Tissue Information | Recombinase Activity | References

Allele Information

Allele:

Slc17a8^{em1(icre/ERT2)Zyliu}
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8; endonuclease-mediated mutation 1, Zhiyong Liu

Driver: Slc17a8
Type: Endonuclease-mediated (Inducible, Recombinase)

Inducer:

tamoxifen

Synonym:

vGlut3-P2A-iCreER

Molecular description:

A plasmid encoding a guide RNA and PAM sequence TGG was designed to introduce a P2A peptide fused to an icre/ERT2 cassette into exon 12, immediately before the stop codon, of the solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8 (Slc17a8) gene. Guide RNA and the cas9 nuclease were introduced into the cytoplasm of C57BL/6N-derived fertilized eggs with well recognized pronuclei.

Find mice (IMSR):

Mouse Strains: 1 strain available Cell Lines: 0 lines available

Additional Tissues:

Slc17a8^{em1(icre/ERT2)Zyliu} activity also observed in:
sensory organs

Tissue Information

Head

Other recombinase alleles with activity in Head tissues:

7630403G23Rik^{Tg(Th-cre)1Tmd}, Abcg2^{tm1.1(cre/Esr1*)Jvbe}, Acan^{tm1(cre/ERT2)Crm}, Acsm4^tm1(cre)Hsak ...(more)

Recombinase Activity

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Assays Genotypic Background Result Notes

References

All for this allele:

5 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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