Gdf15<tm1(cre/ERT2)Amc> - Renal & Urinary System Recombinase Activity Detail MGI Mouse

Gdf15^{tm1(cre/ERT2)Amc} - Renal & Urinary System
Recombinase Activity Detail

Allele Information | Tissue Information | Recombinase Activity | References

Allele Information

Allele:

Gdf15^{tm1(cre/ERT2)Amc}
growth differentiation factor 15; targeted mutation 1, Andrew P McMahon

Driver: Gdf15
Type: Targeted (Inducible, Recombinase)

Inducer:

tamoxifen

Synonym:

Gdf15^nuGFP-CE

Molecular description:

Recombinase mediated cassette exchange (RMCE) replaced the fragment between FRT and the third loxP which contained lacZ , neomycin and exon 2 sequences located in intron 1 of the Gdf15 allele with the following - an FRT site, En2 splice acceptor, P2A, nuclear GFP, F2A, cre/ERT2, polyA and a rox-flanked puromycin resistance cassette followed by a loxP site.

Find mice (IMSR):

Mouse Strains: 1 strain available Cell Lines: 0 lines available

Tissue Information

Renal & Urinary System

Other recombinase alleles with activity in Renal & Urinary System tissues:

Abcg2^{tm1.1(cre/Esr1*)Jvbe}, Agrp^tm1(cre)Lowl, Alpl^tm1(cre)Nagy, Amn^{em1(cre/ERT2)Fuzh} ...(more)

Recombinase Activity

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Assays Genotypic Background Result Notes

References

All for this allele:

2 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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