Ntsr1<tm1.1(cre)Giml> - Nervous System Recombinase Activity Detail MGI Mouse

Ntsr1^{tm1.1(cre)Giml} - Nervous System
Recombinase Activity Detail

Allele Information | Tissue Information | Images | Recombinase Activity | References

Allele Information

Allele:

Ntsr1^{tm1.1(cre)Giml}
neurotensin receptor 1; targeted mutation 1.1, Gina M Leinninger

Driver: Ntsr1
Type: Targeted (Recombinase)

Synonym:

NtsR1^deltaNEO-Cre, NtsR1^Dev

Molecular description:

The targeting vector was generated by inserting an IRES-Cre between the stop codon and the polyadenylation site of the sequence encoding the 3' end of the mouse NtsR1 gene, with an frt-flanked NEO cassette placed upstream of the IRES-Cre. Correctly recombined ES clones via homologous recombination were expanded, and injected into mouse blastocystes to generate chimeric males. Mice were bred to a FlpO deleter line to remove neo cessette to make constitutive cre expression throughout life.

Find mice (IMSR):

Mouse Strains: 1 strain available Cell Lines: 0 lines available

Additional Tissues:

Ntsr1^{tm1.1(cre)Giml} activity also observed in:
head

Tissue Information

Nervous System

Other recombinase alleles with activity in Nervous System tissues:

7630403G23Rik^{Tg(Th-cre)1Tmd}, Abcg2^{tm1.1(cre/Esr1*)Jvbe}, Acsm4^tm1(cre)Hsak, Adcyap1r1^{tm1.1(cre/GFP)Rpa} ...(more)

Images

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J:263745 Fig. 2

Recombinase Activity

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Assays Genotypic Background Result Notes

References

All for this allele:

2 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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