Ly6a<tm1.1(cre)Jmol> - Cardiovascular System Recombinase Activity Detail MGI Mouse

Ly6a^{tm1.1(cre)Jmol} - Cardiovascular System
Recombinase Activity Detail

Allele Information | Tissue Information | Recombinase Activity | References

Allele Information

Allele:

Ly6a^{tm1.1(cre)Jmol}
lymphocyte antigen 6 family member A; targeted mutation 1.1, Jeffery D Molkentin

Driver: Ly6a
Type: Targeted (Null/knockout, Recombinase)

Synonym:

Ly6a^Cre

Molecular description:

A cDNA encoding cre-IRES-EGFPnls (nuclear localized EGFP) as well as an FRT-flanked neomycin cassette was recombined in-frame with the Ly6a ATG start codon (exon 2) via homologous recombination. Resultant mice were crossed with Flpe mice to delete the neomycin cassette. Though present in the targeting construct, IRES-driven expression of EGFPnls is not observed. Expression of Ly6a is eliminated by the targeted allele.

Find mice (IMSR):

Mouse Strains: 1 strain available Cell Lines: 0 lines available

Tissue Information

Cardiovascular System

Other recombinase alleles with activity in Cardiovascular System tissues:

A1cf^{Tg(Myh6-cre/Esr1*)1Jmk}, Abcg2^{tm1.1(cre/Esr1*)Jvbe}, Aldh1l1^{em1(cre/ERT2)Nju}, Alpl^tm1(cre)Nagy ...(more)

Recombinase Activity

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Assays Genotypic Background Result Notes

References

All for this allele:

1 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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